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    Cape Girardeau, MO Retail Properties & Spaces for Lease

    15 results
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    Renovated Commercial Space For Lease
    $2,500 / Mo
    2,937 SF

    Renovated Commercial Space For Lease

    230 N Sprigg St, Cape Girardeau, MO 63701

    Renovated commercial space with high visibility in a prime location.

    • Prime location with high traffic and road frontage on N Sprigg St, offering excellent visibility in the Business District.
    • Almost 3000 sq ft of renovated space suitable for multiple offices or service providers.
    • Completely renovated with brand new A/C, roof, gutters, flooring, fixtures, bathrooms, kitchenette, and siding.
    • Significant rental income potential.
    • Located downtown, in the midst of exciting activities.
    Updated: Jun 30, 2025
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    Mixed-Use Commercial Space Available
    $1,900 / Mo

    Mixed-Use Commercial Space Available

    2117 Broadway St, Cape Girardeau, MO 63701

    Versatile storefront and warehouse space in downtown Cape Girardeau.

    • Prime location on Broadway Street, a high‑traffic commercial corridor in Cape Girardeau.
    • Versatile mixed‑use space: 1,000 SF storefront and 1,400 SF warehouse.
    • Flexible layout suitable for retail, wholesale, service, or light industrial operations.
    • Storefront is fully heated and cooled with a dedicated restroom.
    • Warehouse includes an overhead door for convenient loading and unloading.
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    Historic Art Deco Landmark Space
    $2,900 / Mo

    Historic Art Deco Landmark Space

    Restored historic building in downtown Cape Girardeau's commercial district.

    824 Broadway St, Cape Girardeau, MO 63701
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    Prime Retail/Office Space Available
    Contact for pricing

    Prime Retail/Office Space Available

    New 2,300 SF space ideal for retail or office.

    3465 William St, Cape Girardeau, MO 63703
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    New Development Retail Space Available
    Contact for pricing

    New Development Retail Space Available

    Prime lease space with high visibility and build-out allowance.

    2510 Veterans Memorial Dr, Cape Girardeau, MO 63701
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    Retail Storefront with Office Space
    Contact for pricing

    Retail Storefront with Office Space

    Downtown retail storefront with office space for rent.

    221 Merriwether St, Cape Girardeau, MO 63703
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    Retail Space Near West Park
    Contact for pricing
    7,908 SF

    Retail Space Near West Park

    Retail space in regional shopping hub with easy Interstate access.

    3047 William St, Cape Girardeau, MO 63703
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    Retail Space Near West Park
    Contact for pricing
    4,970 SF

    Retail Space Near West Park

    Retail space in regional shopping hub with high visibility.

    3036-3048 William St, Cape Girardeau, MO 63703
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    Retail Space Near West Park
    Contact for pricing
    1,595 SF

    Retail Space Near West Park

    Retail space available in regional shopping hub near West Park.

    240-250 S Silver Springs Rd, Cape Girardeau, MO 63703
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    Retail Space Near Interstate 55
    Contact for pricing
    10,800 SF

    Retail Space Near Interstate 55

    Retail space in regional shopping hub with interstate access.

    258 Siemers Dr, Cape Girardeau, MO 63701
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    Regional Shopping Center Near I-55
    Contact for pricing
    9,400 SF

    Regional Shopping Center Near I-55

    Regional shopping center with easy access to Interstate 55.

    155-157 Siemers Dr, Cape Girardeau, MO 63701
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    Retail Space Near St. Francis
    Contact for pricing
    3,154 SF

    Retail Space Near St. Francis

    Retail space available across from St. Francis Medical Center.

    3049 Williams St, Cape Girardeau, MO
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    West Park Mall Medical Office Space
    Contact for pricing
    79,122 SF

    West Park Mall Medical Office Space

    Missouri medical office suites for lease

    3049 William St, Cape Girardeau, MO 63703
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    West Park Strip Center Retail Space
    Contact for pricing
    23,464 SF

    West Park Strip Center Retail Space

    High-traffic retail center; two spaces available.

    250 Silver Springs Rd, Cape Girardeau, MO 63703
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    Lambert Plaza Retail Space
    Contact for pricing
    46,692 SF

    Lambert Plaza Retail Space

    Cape Girardeau, MO Retail Opportunity

    155 Siemers Dr, Cape Girardeau, MO 63701
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    Based on your search, we've compiled 36 Potential Opportunities for your consideration. Besides 15 Active listings in Cape Girardeau, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 17 Properties for Sales.

    Explore Retail properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Space in High-Traffic Location
    $1,440 / Mo

    Retail Space in High-Traffic Location

    Retail space with signage, parking, and delivery entrance available for lease.

    2931 E Jackson Blvd, Jackson, MO 63755
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    Retail Space in High Traffic Area
    $1,440 / Mo
    34,761 SF

    Retail Space in High Traffic Area

    Retail space in Jackson, MO with high visibility.

    2931 E Jackson Blvd, Jackson, MO 63755
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    Charleston Retail or Office Space
    Contact for pricing

    Charleston Retail or Office Space

    Retail or office space with excellent visibility and parking.

    114 W Commercial St, Charleston, MO 63834
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    Charleston Retail Space - Main Street
    Contact for pricing
    8,351 SF

    Charleston Retail Space - Main Street

    High-traffic retail space, 8,351 sq ft.

    601 Main St, Charleston, MO 63834
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    Explore Similar Spaces for Sale in Cape Girardeau, MO

    Consider Similar Space for Sale. We found 17 Spaces in Nearby Locations matching your search parameters.

    Versatile Riverfront Commercial Property
    Pending
    $400,000
    4,400 SF

    Versatile Riverfront Commercial Property

    Prime riverfront property suitable for office, restaurant, warehouse, or mixed-use.

    450 N Main St, Cape Girardeau, MO 63701
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    Versatile Commercial Space in Missouri
    $900,000
    7,396 SF

    Versatile Commercial Space in Missouri

    7,396 SF commercial building with banquet, dining, and bar areas.

    20 N Spanish St, Cape Girardeau, MO 63701
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    Versatile Commercial Property For Sale
    $295,000
    2,920 SF

    Versatile Commercial Property For Sale

    High-visibility commercial property with flexible layout and spacious attached warehouse.

    225 Clark Ave, Cape Girardeau, MO 63701
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    Versatile Commercial Building in Cape
    $225,000
    0.57 Acres

    Versatile Commercial Building in Cape

    Adaptable 1800 sq ft commercial building in thriving Cape Girardeau.

    2357 Rust Ave, Cape Girardeau, MO 63703
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    Renovated Commercial Space in Cape Girardeau
    $239,900
    2,937 SF

    Renovated Commercial Space in Cape Girardeau

    Renovated commercial space with high potential in a prime location.

    230 N Sprigg St, Cape Girardeau, MO 63701
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    Broadway Commercial Space with Apartment
    $280,000
    5,100 SF

    Broadway Commercial Space with Apartment

    Versatile investment opportunity with remodeled apartment and commercial space.

    520 Broadway St, Cape Girardeau, MO 63701
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    Prime Retail Space in Cape
    Contact for pricing

    Prime Retail Space in Cape

    4,500 SF retail space in historic downtown Cape Girardeau.

    731 Broadway St, Cape Girardeau, MO 63701
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    Cape Girardeau Retail Opportunity
    Contact for pricing

    Cape Girardeau Retail Opportunity

    46,000 SF retail space in West Cape Centre.

    201 S Broadview St, Cape Girardeau, MO 63703
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    Retail/Office Space Near I-55
    Contact for pricing

    Retail/Office Space Near I-55

    Prime location near I-55 and West Park Mall.

    3065 William St, Cape Girardeau, MO 63703
    View details

    Cape Girardeau, MO Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in Cape Girardeau, MO with 32 listings featured on our commercial real estate exchange. The current inventory includes 127,935,720 square feet of properties with an estimated lease value of $10 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Cape Girardeau, MO begin at $10 SF/Yr, with an average of $10 SF/Yr and extend to $10 SF/Yr.
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    Browse Retail properties & Spaces for Lease Near Cape Girardeau, MO

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    Most Searched ZIP Codes in Cape Girardeau, MO

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