Cape Girardeau, MO Commercial Real Estate for Sale

List

Map

Mc Clure, IL Scott City, MO Jackson, MO Joplin, MO Thebes, IL Chaffee, MO Delta, MO Wolf Lake, IL

83 properties

Sort:

Updated: Apr 15

Renovated Office Building

230 N Sprigg Street, Cape Girardeau, MO 63701

$239,900

2,937 sqft 0.25 AC lot

2,937 SF renovated office building on a 0.252‑acre site
New roof, gutters, siding, flooring, fixtures, bathrooms, and kitchenette
Brick construction with flat roof, forced‑air heat, and electric central air
Road frontage on N Sprigg Street in Cape Girardeau’s Business District
Open parking lot with public water and public sewer

View details

Updated: Jul 30

Flex Space with Showroom

3082 County Road 620, Cape Girardeau, MO 63701

$650,000

1.37 AC lot

7,200 square feet across showroom, shop, and upstairs expansion areas
Approximately 2,400 square feet of finished showroom space
3,600‑square‑foot shop area for commercial or industrial operations
1,200 square feet upstairs framed for future completion
Two large garage doors and on‑site parking

View details

Restaurant Building with Banquet Space

20 N Spanish Street, Cape Girardeau, MO 63701

$799,000

0.17 AC lot

Versatile restaurant layout includes dining, banquet, bar, kitchen, and covered patio areas in downtown Cape Girardeau.

View details

See what stands out in Cape Girardeau County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

Cap Rate available after sign in

NOI available after sign in

Local Demand available after sign in

Retail Building with Drive-Through

5 S Kingshighway, Cape Girardeau, MO 63703

$1,650,000

3,483 sqft 0.80 AC lot

The C2-zoned site includes paved off-street parking and a drive-through window.

View details

Equipped Sports Bar Property

26 N Main Street, Cape Girardeau, MO 63701

$795,000

0.20 AC lot

Sale includes the building, bar business, commercial kitchen, and entertainment equipment.

View details

Corner Bar and Pub Building

632 Broadway Street, Cape Girardeau, MO 63701

$1,200,000

0.36 AC lot

Renovated kitchen, patio, and accessible exterior restrooms support food-and-beverage operations.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Brick Flex Space with Warehouse

333 N Main Street, Cape Girardeau, MO 63701

$425,000

0.25 AC lot

Brick commercial property combining warehouse capacity and finished offices in a downtown Cape Girardeau setting.

View details

Two-Level Office Building For Sale

10 Doctors Park, Cape Girardeau, MO 63703

$815,000

9,857 sqft 0.44 AC lot

9,857 SF office building with multiple offices and restrooms.

View details

Operational Car Wash with Updated Equipment

1004 William Street, Cape Girardeau, MO 63703

$119,900

0.51 AC lot

Fully operational car wash with cash and card payment systems.

View details

Corner Conventional Restaurant Property

45 S Kingshighway, Cape Girardeau, MO 63703

$2,500,000

0.85 AC lot

Established restaurant property with highway and interstate frontage, public water, and an on-site parking lot.

View details

Downtown Office Building For Sale

18 N. Main, Cape Girardeau, MO 63701

$899,900

13,694 sqft

13,694 SF office building in historic downtown Cape Girardeau.

View details

Historic Office Condominium Units

937 Broadway Street, Cape Girardeau, MO 63701

$99,000

4,300 sqft

Multiple commercial condominium suites in a brick downtown building with central air, public water, and public sewer.

View details

Brick Storefront Property

525 Broadway Street, Cape Girardeau, MO 63701

$189,000

0.10 AC lot

Downtown commercial building with flexible unfinished interior space and rear service access.

View details

Renovated Mid-Century Office Building

429 N Broadview St, Cape Girardeau, MO 63701

$1,690,000

10,000 sqft

Updated office building with multiple private offices, conference rooms, and an event space with bar and projection screen.

View details

C-2 Commercial Land with Existing Structure

1931 N Kingshighway Street, Cape Girardeau, MO 63701

$459,000

0.80 AC lot

Highway commercial zoning supports renovation, repurposing, or redevelopment of the existing structure.

View details

Commercial Development Land

367 S Broadview Street, Cape Girardeau, MO 63703

$629,000

3.00 AC lot

Commercial-zoned land with water available for future development.

View details

Cape Girardeau Medical Office Building

62 Doctors Park, Cape Girardeau, MO 63703

$270,000

2,546 sqft 0.43 AC lot

2,546 SF medical office building in a thriving complex.

View details

Renovated Mid-Century Office Building

429 N Broadview Street, Cape Girardeau, MO 63701

$1,690,000

1.37 AC lot

Updated workspace includes private offices, meeting rooms, shared work areas, and an event room with bar and projection screen.

View details

Freestanding Single-Tenant Restaurant

2406 William Street, Cape Girardeau, MO 63703

Contact for pricing

5,030 sqft 1.01 AC lot

Freestanding single-tenant restaurant on an absolute NNN lease structure with a brand-new 10-year term.

View details

Brick Office Building

824 Independence Street, Cape Girardeau, MO 63703

$350,000

0.42 AC lot

Updated professional property with on-site parking, central air, and a mix of carpet and linoleum flooring.

View details

Commercial Land with Lot Division Plan

1000 North Mt Auburn Road, Cape Girardeau, MO 63701

$265,000

31,363 sqft

Commercial acreage along Mount Auburn Road with a proposed plan for three smaller lots.

View details

Commercial Land with Public Water

1980 Golden Eagle Court, Cape Girardeau, MO 63701

$395,000

2.39 AC lot

Commercial land with public water service and several stated commercial use options.

View details

Versatile Commercial Space in Downtown

20 N Spanish Street, Cape Girardeau, MO 63701

Contact for pricing

7,396 sqft

7,396 SF commercial building with multiple dining areas.

View details

Two-Story Office Building

2711 Thomas Drive, Cape Girardeau, MO 63701

$500,000

0.49 AC lot

Leased brick office property with lower-level garage space, central air, and public water.

View details

Cape Girardeau, MO Commercial Real Estate Market Trends and Statistics

Explore 83 commercial real estate for sale in Cape Girardeau, MO, showcased through 83 active listings on our real estate platform. These investment opportunities span a total of 363,902 square feet of properties for sale, with an estimated market value of $36,209,450.

Sale prices for business properties in Cape Girardeau, MO start at $47,900, averaging $754,363, and reaching up to $3,327,750 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

List

Map

Demographics Overview

Population 47K

Population Growth (5Y) +1.2%

Median Household Income $62,338

College Educated 29.0%

High-Yield Neighborhoods for Investment

Identify Cape Girardeau submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
63703	$457K
63701	$1M

Taxes & Financing

Tax Rate (average for all types) 5.29%

Property Tax per SF $93.92 per SF

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Cape Girardeau County

New Delisted

Total CRE Inventory on Market (SF)

Need Help?

Reach out if you need assistance with Realmo tools or have questions about your listings

Cape Girardeau, MO Commercial Real Estate for Sale

230 N Sprigg Street, Cape Girardeau, MO 63701

3082 County Road 620, Cape Girardeau, MO 63701

20 N Spanish Street, Cape Girardeau, MO 63701

5 S Kingshighway, Cape Girardeau, MO 63703

26 N Main Street, Cape Girardeau, MO 63701

632 Broadway Street, Cape Girardeau, MO 63701

333 N Main Street, Cape Girardeau, MO 63701

10 Doctors Park, Cape Girardeau, MO 63703

1004 William Street, Cape Girardeau, MO 63703

45 S Kingshighway, Cape Girardeau, MO 63703