Cape Girardeau, MO
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    Cape Girardeau, MO Medical Centers for Sale

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    Mc Clure, IL Scott City, MO Jackson, MO
    Ambulatory Surgery Center Investment Opportunity
    $8,050,000
    13,650 SF
    Ambulatory Surgery Center Investment Opportunity

    3241 Percy Drive, Cape Girardeau, MO 63701

    Single-tenant surgery center near St. Francis Medical Center for sale.
    • 13,650 sq. ft. single‑tenant ambulatory surgery center.
    • Located directly across from St. Francis Medical Center (Level III trauma center).
    • Turnkey investment with 2 years remaining on the current lease and 2% annual rental increases.
    • New, state‑of‑the‑art HVAC system (valued at over $800,000).
    • Specializes in key medical areas (ENT, general surgery, gynecology, ophthalmology, orthopedics, retinal).
    Updated: Sep 9, 2025
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    Versatile Commercial Building on 1.9 Acres
    $2,900,000
    13,458 SF
    Versatile Commercial Building on 1.9 Acres

    1429 N Mount Auburn Road, Cape Girardeau, MO 63701

    All-brick commercial building with abundant parking and multiple use opportunities.
    • Versatile commercial building suitable for multiple uses
    • Potential for dual income stream: owner‑occupy main level and lease lower level
    • Abundant parking with 70+ spaces and a large front entry canopy
    • Well‑maintained building with recent updates including remodeled interior
    • Equipped with a 2,000 lb capacity elevator
    Updated: Dec 7, 2024
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    Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 2 Active listings in Cape Girardeau, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Building in Poplar Bluff
    $325,000
    12,351 SF
    Versatile Building in Poplar Bluff

    12351 SF building suitable for various purposes in Poplar Bluff.

    338 Hazel St, Poplar Bluff, MO 63901

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    Dental Investment Opportunity in Paducah
    $2,098,286
    7,500 SF
    Dental Investment Opportunity in Paducah

    Net leased dental practice in growing healthcare corridor.

    1836 Broadway St, Paducah, KY 42001

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    Poplar Bluff Ambulance Base
    $937,500
    Poplar Bluff Ambulance Base

    Mission-critical ambulance base in central Poplar Bluff, Missouri.

    414 N 5th St, Poplar Bluff, MO 63901

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    Paducah Ambulatory Surgery Center
    Contact for pricing
    21,236 SF
    Paducah Ambulatory Surgery Center

    21,236 SF ambulatory surgery center for sale.

    2831 Lone Oak Rd, Paducah, KY 42003

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    72.72 Acres in Brownsville, TN
    $890,000
    72.72 Acres
    72.72 Acres in Brownsville, TN

    Large parcel in high-traffic area with utilities and hospital proximity.

    N Washington Avenue, Brownsville, TN 38012

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    Arlington Land For Sale
    $9,900,000
    27.35 Acres
    Arlington Land For Sale

    27.35 acres of mixed-use development land in Arlington, TN.

    MILTON WILSON Blvd, Arlington, TN 38002

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    Prime Commercial Land on Highway
    $1,490,000
    4.40 Acres
    Prime Commercial Land on Highway

    4.4-acre commercial land with highway frontage near future developments.

    Highway 54, Osage Beach, MO 65065

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    Prime Commercial Land on Highway
    $1,490,000
    4.40 Acres
    Prime Commercial Land on Highway

    4.4-acre commercial land with highway frontage near future developments.

    Hwy 54, Osage Beach, MO 65065

    View details

    Cape Girardeau, MO Medical Centers Investment Opportunities Market Analysis

    Explore 2 medical centers for sale in Cape Girardeau, MO on our real estate platform. These investment opportunities span a total of 27,108 square feet of properties for sale, with an estimated market value of $10,950,000.

    Sale prices for medical buildings in Cape Girardeau, MO start at $2,900,000, averaging $5,475,000, and reaching up to $8,050,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Medical centers 2
    Medical space 1

    Demographics Overview

    Population 47K
    Population Growth (5Y) +1.2%
    Median Household Income $62,338
    College Educated 29.0%

    High-Yield Neighborhoods for Investment

    Identify Cape Girardeau submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63701 $5.5M

    Taxes & Financing

    Tax Rate (average for all types) 5.29%
    Property Tax per SF $93.92 per SF
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Cape Girardeau County

    New Delisted

    Total CRE Inventory on Market (SF)

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