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Cape Girardeau, MO Healthcare Properties for Sale

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Ambulatory Surgery Center Investment Opportunity
$8,050,000
13,650 SF

Ambulatory Surgery Center Investment Opportunity

3241 Percy Drive, Cape Girardeau, MO 63701

Single-tenant surgery center near St. Francis Medical Center for sale.

  • 13,650 sq. ft. single‑tenant ambulatory surgery center.
  • Located directly across from St. Francis Medical Center (Level III trauma center).
  • Turnkey investment with 2 years remaining on the current lease and 2% annual rental increases.
  • New, state‑of‑the‑art HVAC system (valued at over $800,000).
  • Specializes in key medical areas (ENT, general surgery, gynecology, ophthalmology, orthopedics, retinal).
Updated: Sep 9, 2025
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Versatile Commercial Building on 1.9 Acres
$2,900,000
13,458 SF

Versatile Commercial Building on 1.9 Acres

1429 N Mount Auburn Road, Cape Girardeau, MO 63701

All-brick commercial building with abundant parking and multiple use opportunities.

  • Versatile commercial building suitable for multiple uses
  • Potential for dual income stream: owner‑occupy main level and lease lower level
  • Abundant parking with 70+ spaces and a large front entry canopy
  • Well‑maintained building with recent updates including remodeled interior
  • Equipped with a 2,000 lb capacity elevator
Updated: Mar 12
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Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 2 Active listings in Cape Girardeau, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 8 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Versatile Building in Poplar Bluff
$325,000
12,351 SF

Versatile Building in Poplar Bluff

12351 SF building suitable for various purposes in Poplar Bluff.

338 Hazel St, Poplar Bluff, MO 63901
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Versatile Commercial Property in Paducah
$1,300,000

Versatile Commercial Property in Paducah

8,100+ sqft commercial space on 1.42 acres for sale.

3538 Lone Oak Rd, Paducah, KY 42003
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Versatile Commercial Building in Poplar Bluff
$325,000
12,351 SF

Versatile Commercial Building in Poplar Bluff

12,351 SF commercial building suitable for various uses.

338 Hazel St, Poplar Bluff, MO 63901
View details
Paducah Ambulatory Surgery Center
Contact for pricing
21,236 SF

Paducah Ambulatory Surgery Center

21,236 SF ambulatory surgery center for sale.

2831 Lone Oak Rd, Paducah, KY 42003
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Paducah Commercial Land
$600,000
1.97 Acres

Prime Paducah Commercial Land

1.97 acres ideal for retail, medical, or restaurant use.

3620 James Sanders Blvd, Paducah, KY 42001
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Prime Commercial Tract in Paducah
$1,475,000
16.50 Acres

Prime Commercial Tract in Paducah

16.5 acre commercial tract with high visibility and access.

3020 Wayne Sullivan Drive, Paducah, KY 42003
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Commercial Land in Poplar Bluff
$399,000
6.64 Acres

Commercial Land in Poplar Bluff

6.64 acres of commercial land ready for development.

3387 Kanell Boulevard, Poplar Bluff, MO 63901
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Fulton Commercial Development Site
$1,150,000
33.60 Acres

Fulton Commercial Development Site

33-acre commercial development site in Fulton, KY, near I-69.

Myatt Road, Fulton, KY 42041
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Explore Off-Market Properties in Cape Girardeau, MO

Consider similar Off-Market properties in Cape Girardeau, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

430 Frederick St

430 Frederick St

HOMES (RETIRED, NURSING) • 11,218 SF
Value Estimation by Request
430 Frederick St, Cape Girardeau, MO 63701-4835
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2906 Beaver Crk Dr

2906 Beaver Crk Dr

HOMES (RETIRED, NURSING) • 6,721 SF
Value Estimation by Request
2906 Beaver Crk Dr, Cape Girardeau, MO 63701-1732
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2525 Boutin Dr

2525 Boutin Dr

HOMES (RETIRED, NURSING) • 26,911 SF
Value Estimation
$575,000
2525 Boutin Dr, Cape Girardeau, MO 63701-8551
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Silver Springs Rd

Silver Springs Rd

Individual retail properties • 4.56 Acres
Value Estimation by Request
0 Silver Springs Rd, Cape Girardeau, MO 63703
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3049 William St

3049 William St

Medical Office Space • 79,122 SF
Value Estimation by Request
3049 William St, Cape Girardeau, MO 63703
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325 Sprigg St

325 Sprigg St

HOMES (RETIRED, NURSING) • 1,913 SF
Value Estimation by Request
325 Sprigg St, Cape Girardeau, MO 63701-5531
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2001 Kingshighway St

2001 Kingshighway St

HOMES (RETIRED, NURSING) • 13,006 SF
Value Estimation by Request
2001 Kingshighway St, Cape Girardeau, MO 63701-2127
View details
2915 Cpe Lacroix Rd

2915 Cpe Lacroix Rd

HOMES (RETIRED, NURSING) • 11,978 SF
Value Estimation by Request
2915 Cpe Lacroix Rd, Cape Girardeau, MO 63701-9766
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Cape Girardeau, MO Healthcare Properties Investment Opportunities Market Analysis

Explore 10 healthcare properties for sale in Cape Girardeau, MO on our real estate platform. These investment opportunities span a total of 27,108 square feet of properties for sale, with an estimated market value of $10,950,000.

Sale prices for medical real estate in Cape Girardeau, MO start at $2,900,000, averaging $5,475,000, and reaching up to $8,050,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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