Cape Girardeau, MO Healthcare Properties for Sale

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Mc Clure, IL Scott City, MO Jackson, MO Chaffee, MO Tamms, IL Delta, MO Wolf Lake, IL Whitewater, MO

Updated: Dec 6, 2024

Versatile Commercial Building on 1.9 Acres

1429 N Mount Auburn Road, Cape Girardeau, MO 63701

$2,900,000

13,458 sqft 1.87 AC lot

Versatile commercial building suitable for multiple uses
Potential for dual income stream: owner‑occupy main level and lease lower level
Abundant parking with 70+ spaces and a large front entry canopy
Well‑maintained building with recent updates including remodeled interior
Equipped with a 2,000 lb capacity elevator

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This listing looks promising.

Here's a quick look at some key insights for

1429 N Mount Auburn Road, Cape Girardeau, MO 63701

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Est. Cap Rate

6.4%
Above avg (5.9%)
Est. NOI

$184K
Annual
Mortgage

$1.61M
Sep 2021

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Updated: Sep 9, 2025

Ambulatory Surgery Center Investment Opportunity

3241 Percy Drive, Cape Girardeau, MO 63701

$8,050,000

13,650 sqft 2.71 AC lot

13,650 sq. ft. single‑tenant ambulatory surgery center.
Located directly across from St. Francis Medical Center (Level III trauma center).
Turnkey investment with 2 years remaining on the current lease and 2% annual rental increases.
New, state‑of‑the‑art HVAC system (valued at over $800,000).
Specializes in key medical areas (ENT, general surgery, gynecology, ophthalmology, orthopedics, retinal).

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Ambulatory Surgery Center

3241 Percy Drive, Cape Girardeau, MO 63701

$8,050,000

13,650 sqft

Single-tenant ambulatory surgery center with recent HVAC upgrades and two years remaining on the current lease.

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Ambulatory Surgery Center Facility

3241 Percy Drive, Cape Girardeau, MO 63701

Contact for pricing

13,650 sqft

For-sale ambulatory surgery center with recently upgraded HVAC and modern systems in a high-visibility medical corridor.

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Two-Level Medical Office Building

53 Doctors Park, Cape Girardeau, MO 63703

$975,000

Two-level medical office space with multiple exam rooms and waiting areas, fully equipped and ready for occupancy.

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Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 5 Active listings in Cape Girardeau, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 8 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Former Restaurant Building with Parking

5598 Us Highway 61 N, Jackson, MO 63755

$549,900

3,096 sqft 0.64 AC lot

Built in 2017 with a maintenance-free exterior and roof, featuring an open floor plan and ample parking.

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Paducah Commercial Building For Sale

3100 Clay Street, Paducah, KY 42001

$275,000

29,781 sqft 1.13 AC lot

29,781 sq ft commercial building in Paducah, Kentucky.

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Paducah Ambulatory Surgery Center

2831 Lone Oak Rd, Paducah, KY 42003

Contact for pricing

21,236 sqft

21,236 SF ambulatory surgery center for sale.

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Turnkey Historic Brick Office Building

23/25/27 W Saint Joseph Street, Perryville, MO 63775

$1,150,000

Fully restored 1859 brick building with updated HVAC including central air and mini-splits, plus multiple income-producing spaces.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Highway 25 Historic Gem

17382 State Highway 25, Dexter, MO 63841

$179,900

7,200 sqft 3.39 AC lot

Historic property on 3+ acres with 7,000+ sqft and potential.

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Commercial Development Land Parcel

3620 James Sanders Blvd, Paducah, KY 42001

$600,000

1.97 AC lot

Nearly 2-acre parcel on James Sanders Blvd near Sam's Club and Jordan's Crossing, suited for retail or medical development.

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Level Commercial Development Tract

3020 Wayne Sullivan Drive, Paducah, KY 42003

$1,475,000

16.50 AC lot

Level 16.5-acre commercial site with city utilities and direct access to Wayne Sullivan Drive.

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Fulton, KY Commercial Development Site

Myatt Road, Fulton, KY 42041

$1,150,000

33.60 AC lot

33-acre commercial development site in Fulton, KY, near I-69.

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Off-Market Properties in Cape Girardeau, MO

Consider similar Off-Market properties in Cape Girardeau, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

HOMES (RETIRED, NURSING)

430 Frederick St, Cape Girardeau, MO 63701-4835

Value Estimation by Request

11,218 sqft 0.16 AC lot

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HOMES (RETIRED, NURSING)

2906 Beaver Crk Dr, Cape Girardeau, MO 63701-1732

Value Estimation by Request

6,721 sqft 0.60 AC lot

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HOMES (RETIRED, NURSING)

2525 Boutin Dr, Cape Girardeau, MO 63701-8551

$575,000

Estimated value

26,911 sqft 12.65 AC lot

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Individual retail properties

0 Silver Springs Rd, Cape Girardeau, MO 63703

Value Estimation by Request

4.56 AC lot

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Medical Office Space

3049 William St, Cape Girardeau, MO 63703

Value Estimation by Request

79,122 sqft

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HOMES (RETIRED, NURSING)

325 Sprigg St, Cape Girardeau, MO 63701-5531

Value Estimation by Request

1,913 sqft 0.66 AC lot

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HOMES (RETIRED, NURSING)

2001 Kingshighway St, Cape Girardeau, MO 63701-2127

Value Estimation by Request

13,006 sqft 10.30 AC lot

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HOMES (RETIRED, NURSING)

2915 Cpe Lacroix Rd, Cape Girardeau, MO 63701-9766

Value Estimation by Request

11,978 sqft 4.49 AC lot

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Cape Girardeau, MO Healthcare Properties Market Trends and Statistics

Explore 13 healthcare properties for sale in Cape Girardeau, MO, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 54,408 square feet of properties for sale, with an estimated market value of $19,975,000.

Sale prices for medical real estate in Cape Girardeau, MO start at $975,000, averaging $4,993,750, and reaching up to $8,050,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 47K

Population Growth (5Y) +1.2%

Median Household Income $62,338

College Educated 29.0%

High-Yield Neighborhoods for Investment

Identify Cape Girardeau submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
63701	$5.5M

Taxes & Financing

Tax Rate (average for all types) 5.29%

Property Tax per SF $93.92 per SF

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Cape Girardeau County

New Delisted

Total CRE Inventory on Market (SF)

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Cape Girardeau, MO Healthcare Properties for Sale

1429 N Mount Auburn Road, Cape Girardeau, MO 63701

3241 Percy Drive, Cape Girardeau, MO 63701

3241 Percy Drive, Cape Girardeau, MO 63701

3241 Percy Drive, Cape Girardeau, MO 63701

53 Doctors Park, Cape Girardeau, MO 63703