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    Cape Girardeau, MO
    Retail

    Cape Girardeau, MO Retail Properties & Spaces for Lease

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    Scott City, MO Jackson, MO
    23 properties
    Renovated Office and Storefront Building
    Updated: Jul 1, 2025
    Renovated Office and Storefront Building

    230 N Sprigg Street, Cape Girardeau, MO 63701

    $2,500/Mo
    2,937 sqft · $10 SF/Yr
    Massive brick building (approx. 3,000 sq ft) with renovated space
    Road frontage on N Sprigg St in a downtown, high‑traffic area
    BRAND NEW A/C, roof, gutters, flooring, fixtures, bathrooms, kitchenette, siding, and newly tuckpointed exterior
    Forced air heating with central air and electric cooling
    Public utilities: public water and public sewer
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    Flexible Restaurant/Retail/Office Suite
    Updated: Jun 2
    Flexible Restaurant/Retail/Office Suite

    820 N Sprigg St - Suites 3-4, Cape Girardeau, MO 63701

    $18 SF/Yr
    3,000 sqft · $4,500/Mo
    3,000 SF commercial lease space with flexible use for restaurant, retail, or office
    Located directly across from Towers Hall at Southeast Missouri State University
    Former restaurant space with existing commercial restaurant infrastructure
    Situated in an established multi‑tenant retail strip with two existing restaurant tenants operating in the center
    High exposure along N Sprigg Street with convenient access and parking
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    Retail Building with Drive-Through Window
    Retail Building with Drive-Through Window

    5 S Kingshighway, Cape Girardeau, MO 63703

    $8,707/Mo
    3,483 sqft · $30 SF/Yr

    Drive-through retail building with off-street paved parking on C2-zoned land, adjacent to major retailers.

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    Retail and Office Storefront
    Retail and Office Storefront

    211 Merriwether St, Cape Girardeau, MO 63703

    $1,000/Mo
    1,300 sqft · $9 SF/Yr

    Flexible 1,300 SF storefront layout with retail frontage and included office spaces, suited for mixed-use operations.

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    Historic Art Deco Landmark Space
    Historic Art Deco Landmark Space

    824 Broadway St, Cape Girardeau, MO 63701

    $2,900/Mo

    Restored historic building in downtown Cape Girardeau's commercial district.

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    Retail Space For Rent
    Retail Space For Rent

    155 Siemers Drive, Cape Girardeau, MO 63701

    $2,024/Mo

    Retail space available for lease in Cape Girardeau, Missouri.

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    Retail Space For Rent
    Retail Space For Rent

    3047 William Street, Cape Girardeau, MO 63701

    $4 SF/Yr

    Retail space available for lease in Cape Girardeau, Missouri.

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    New Development Retail Space Available
    New Development Retail Space Available

    2510 Veterans Memorial Drive, Cape Girardeau, MO 63701

    Contact for pricing
    10,000 sqft

    Prime lease space with high visibility and build-out allowance.

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    Prime Retail/Office Space Available
    Prime Retail/Office Space Available

    3465 William, Cape Girardeau, MO 63703

    Contact for pricing
    2,300 sqft

    New 2,300 SF space ideal for retail or office.

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    Versatile Commercial Space on Kingshighway
    Versatile Commercial Space on Kingshighway

    500 N Kingshighway St, Cape Girardeau, MO 63701

    Contact for pricing
    3,500 sqft

    3,500 SF commercial property suitable for retail, office, or service.

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    Retail Storefront with Office Space
    Retail Storefront with Office Space

    221 Merriwether Street, Cape Girardeau, MO 63703

    Contact for pricing
    1,275 sqft

    Downtown retail storefront with office space for rent.

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    Retail Space in Cape Girardeau
    Retail Space in Cape Girardeau

    3049 William Street, Cape Girardeau, MO 63703

    Contact for pricing

    Retail space available for lease in Cape Girardeau, Missouri.

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    Retail Space Available For Rent
    Retail Space Available For Rent

    3036 William St, Cape Girardeau, MO 63701

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    Retail space for rent in Cape Girardeau, Missouri.

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    Retail Space in Cape Girardeau
    Retail Space in Cape Girardeau

    250 South Silver Springs Road, Cape Girardeau, MO 63701

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    Retail property for lease in Cape Girardeau, Missouri.

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    Restaurant-Ready Office/Retail Suite
    Restaurant-Ready Office/Retail Suite

    820 N Sprigg St, Cape Girardeau, MO 63701

    Contact for pricing
    3,000 sqft

    Suite 1 offers an open layout and existing restaurant infrastructure with street visibility across from Towers Hall.

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    Retail Space in Cape Girardeau
    Retail Space in Cape Girardeau

    230 N Sprigg Street, Cape Girardeau, MO 63701

    $12 SF/Yr
    2,937 sqft · $2,937/Mo

    Retail space available for rent in Cape Girardeau, Missouri.

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    Retail Space Near St. Francis
    Retail Space Near St. Francis

    3049 Williams St, Cape Girardeau, MO

    Contact for pricing
    3,154 sqft

    Retail space available across from St. Francis Medical Center.

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    Regional Shopping Center Near I-55
    Regional Shopping Center Near I-55

    155-157 Siemers Dr, Cape Girardeau, MO

    Contact for pricing
    9,400 sqft

    Regional shopping center with easy access to Interstate 55.

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    Commercial Space For Lease
    Commercial Space For Lease

    3049 William St, Cape Girardeau, MO 63703

    Contact for pricing

    Commercial space available for lease at 3049 William St.

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    Retail Space Near West Park
    Retail Space Near West Park

    3036-3048 William St, Cape Girardeau, MO

    Contact for pricing
    4,970 sqft

    Retail space in regional shopping hub with high visibility.

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    Retail Space Near West Park
    Retail Space Near West Park

    240-250 S Silver Springs Rd, Cape Girardeau, MO

    Contact for pricing
    1,595 sqft

    Retail space available in regional shopping hub near West Park.

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    Retail Space Available For Rent
    Retail Space Available For Rent

    3036 William Street, Cape Girardeau, MO 63701

    Contact for pricing
    4,970 sqft

    Retail space available, offering 4,970 square feet.

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    Commercial Space For Lease
    Commercial Space For Lease

    155 Siemers Dr, Cape Girardeau, MO 63701

    Contact for pricing

    Commercial space available for lease in Cape Girardeau, Missouri.

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    Based on your search, we've compiled 40 Potential Opportunities for your consideration. Besides 23 Active listings in Cape Girardeau, MO, we suggest exploring alternatives. Similar 17 Properties for Sales.

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    Warehouse with Showroom and Shop Space
    Warehouse with Showroom and Shop Space

    3082 County Road 620, Cape Girardeau, MO 63701

    $700,000
    7,200 sqft · 1.37 AC lot

    Purchase a 7,200 SF warehouse with dedicated showroom, shop area, and framed upstairs space for flexible business or storage needs.

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    Cape Girardeau, MO Retail properties & Spaces Market Trends and Statistics

    Explore Retail properties & Spaces leasing options in Cape Girardeau, MO with 23 listings featured on our commercial real estate exchange. The current inventory includes 13,657 square feet of properties with an estimated lease value of $79 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Cape Girardeau, MO begin at $9 SF/Yr, with an average of $15 SF/Yr and extend to $30 SF/Yr.
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