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    South San Francisco, CA Office Units for Sale

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    San Bruno, CA Brisbane, CA Colma, CA
    Versatile Showroom Warehouse in Peninsula
    $1,100,000
    2,720 SF
    Versatile Showroom Warehouse in Peninsula

    1435 Huntington Avenue #C, South San Francisco, CA 94080

    Functional industrial space in South San Francisco's commercial hub.
    • Prime location in South San Francisco with quick access to Highways 101, 280, and 380.
    • Versatile space suitable for showroom, workspace, light industrial use, offices, design studios, or storage.
    • Flexible layout with approximately 1,560 sq. ft. on the ground floor and 1,160 sq. ft. loft area.
    • Functional design with a grade level roll‑up door for convenient loading and deliveries.
    • Suitable for owner‑user or investor.
    Updated: Mar 19
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    Commercial Property - SOUTH SAN FRANCISCO, CA
    $48,000,000
    21,552 SF
    Commercial Property - SOUTH SAN FRANCISCO, CA

    560 Eccles AVE, South San Francisco, CA 94080

    Manufacturing properties · 21,552 SF
    • Mission‑critical biotech facility with a federal tenant, providing a secure and stable investment.
    • Purpose‑built in 2019 with specialized laboratory infrastructure including entomology and botany labs with high‑purity reverse osmosis water systems.
    • Advanced security features including Lenel card reader system, 24‑hour CCTV, shatter‑resistant blast‑mitigation windows, and fenced parking.
    • Redundant power systems with a 500kW stand‑alone diesel generator and dedicated UPS backup.
    • Streamlined logistics with 4 interior dock‑high doors and a secure devanning area for 53‑foot tractor‑trailers.
    Updated: May 20
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    Combined Flex Space Units
    $799,000
    2,208 SF
    Combined Flex Space Units

    Combined flex space units with office and warehouse areas.

    451 Victory Avenue #4, South San Francisco, CA 94080

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    Mixed-Use Property in Downtown South
    $1,799,000
    2,760 SF
    Mixed-Use Property in Downtown South

    Mixed-use property in a thriving downtown location with high visibility.

    20 Linden Ave, South San Francisco, CA 94080

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    Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 4 Active listings in South San Francisco, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    San Bruno Commercial Building For Sale
    $998,000
    San Bruno Commercial Building For Sale

    Commercial building in the heart of the Central Business District.

    508 San Mateo Ave, San Bruno, CA 94066

    View details
    Versatile Commercial Condo in Yosemite
    $575,000
    911 SF
    Versatile Commercial Condo in Yosemite

    911 sq ft commercial condo ideal for various business uses.

    1555 Yosemite Avenue #11, San Francisco, CA 94124

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    Industrial Property with Commercial Kitchen
    $3,500,000
    7,000 SF
    Industrial Property with Commercial Kitchen

    Rare San Francisco industrial property with a fully equipped commercial kitchen.

    1400 Yosemite Ave, San Francisco, CA 94124

    View details
    Office Space on El Camino
    Contact for pricing
    Office Space on El Camino

    Office space for sale with great visibility and access.

    Colma, CA 94014

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    South San Francisco, CA Office Units Investment Opportunities Market Analysis

    Explore 4 office units for sale in South San Francisco, CA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 29,240 square feet of properties for sale, with an estimated market value of $51,698,000.

    Sale prices for office units in South San Francisco, CA start at $799,000, averaging $12,924,500, and reaching up to $48,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 42
    Office buildings 7
    Medical Office Space 3
    Coworking space 2

    Property Size Breakdown

    The majority of commercial real estate listings in South San Francisco fall within the 100,000+ square foot range.

    Demographics Overview

    Population 65K
    Population Growth (5Y) -3.8%
    Median Household Income $135,966
    College Educated 26.3%

    High-Yield Neighborhoods for Strategic Investment

    Identify South San Francisco submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    94080 $12.9M

    Taxes & Financing

    Tax Rate (average for all types) 1.16%
    Property Tax per SF $7.35 per sq ft
    Tax Rate vs County Average 0.02 pp below county avg
    Average Loan-to-Value 65.0%

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