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    South Carolina Office Units for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    Showing 24 of 1,028 listings
    Flexible Coworking Office Suite
    Contact for pricing
    Flexible Coworking Office Suite

    Fifth-floor open-plan coworking with meeting rooms, kitchen, and onsite amenities near transit.

    1501 Main St, Suite 501, Columbia, SC 29201

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    North Charleston Office/Warehouse Space
    Contact for pricing
    2,500 SF
    North Charleston Office/Warehouse Space

    Office and warehouse space in North Charleston near airport.

    3215 Fortune Drive # 103, North Charleston, SC 29418

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    Lower-Level Office Suite with Lab Room
    Contact for pricing
    Lower-Level Office Suite with Lab Room

    Lower-level suite with private offices, conference room, and lab/work room for medical or professional operations.

    1405 Grove Road, Greenville, SC 29605

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    Simpsonville Flex Space For Rent
    Contact for pricing
    24,635 SF
    Simpsonville Flex Space For Rent

    Flex space featuring warehouses, shops, and office space available for lease.

    514 Palmetto Dr, Simpsonville, SC 29681

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    Johns Island Freestanding Building
    $25 SF/Yr
    5,000 SF
    Johns Island Freestanding Building

    Move-in ready 5,000 SF building on Johns Island.

    3600 J Henry Cut, Johns Island, SC

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    Two-Story Freestanding Office Building
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    Two-Story Freestanding Office Building

    Entire first floor is available in a centrally located, medically oriented freestanding office building with ample parking.

    2125 Charlie Hall Boulevard #First Floor, Charleston, SC 29414

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    Brighton Park Boulevard Office Space
    $35 SF/Yr
    1,260 SF
    Brighton Park Boulevard Office Space

    Class A office space in Nexton Square available for lease.

    318 Brighton Park Blvd, Summerville, SC

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    Freestanding Retail/Office Space
    Contact for pricing
    Freestanding Retail/Office Space

    Former salon space with a large roadside sign and dedicated front-door parking for retail, office, or service use.

    936 Savannah Highway, Charleston, SC 29407

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    Full-Floor Office Suite
    Contact for pricing
    Full-Floor Office Suite

    Full-floor office suite with private offices, conference room, reception area, and two in-suite restrooms.

    1417 Stuart Engals Blvd., Mount Pleasant, SC 29464

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    Renovated Office Suites For Lease
    Contact for pricing
    2,000 SF
    Renovated Office Suites For Lease

    Recently renovated office suites near Swamp Rabbit Trail available for lease.

    8 Sycamore Drive, Greenville, SC 29607

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    Retail and Office Space Available
    $30 SF/Yr
    1,816 SF
    Retail and Office Space Available

    Retail and medical office spaces for lease in Rock Hill.

    2460 India Hook Rd, Rock Hill, SC

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    Summerville Office/Retail Space Available
    Contact for pricing
    1,252 SF
    Summerville Office/Retail Space Available

    1,252 SF free-standing office/retail space for lease.

    216 W 7th North Street, Summerville, SC 29483

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    Versatile Workspace Solutions Available
    Contact for pricing
    Versatile Workspace Solutions Available

    Flexible office spaces, coworking, meeting rooms, and virtual office options.

    1600 Williams Street, 2nd Floor, Columbia, SC 29201

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    Medical Office Condo End Cap
    Contact for pricing
    Medical Office Condo End Cap

    End cap medical office condo with private offices, conference space, and parking within a professional park.

    5401 Netherby Lane Ste 601, North Charleston, SC 29420

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    Warehouse with Office and Restroom
    Contact for pricing
    800 SF
    Warehouse with Office and Restroom

    Warehouse space with office and restroom in prime location.

    1141 Clements Ferry Road, C, Charleston, SC 29492

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    Office Space in Greer, SC
    $1.98 SF/Yr
    910 SF
    Office Space in Greer, SC

    910 SF office space available for rent in Greer.

    103 Pennsylvania Ave, Greer, SC

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    Downtown Rock Hill Office/Retail Space
    Contact for pricing
    2,408 SF
    Downtown Rock Hill Office/Retail Space

    Adaptive reuse space in downtown Rock Hill near Winthrop University.

    Chatham Ave 300, Rock Hill, SC

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    Office/Warehouse Space Near Interstates
    Contact for pricing
    1,500 SF
    Office/Warehouse Space Near Interstates

    1,500 SF office/warehouse space off Dorchester Rd Corridor.

    2652 Bonds Avenue # 201, North Charleston, SC 29405

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    Industrial Suite with Office Space
    Contact for pricing
    2,805 SF
    Industrial Suite with Office Space

    Flex space with warehouse and office, available April 1, 2026.

    9481 Industrial Center Drive Unit 3, Ladson, SC 29456

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    Flex Space with Office and Warehouse
    Contact for pricing
    Flex Space with Office and Warehouse

    Flex suite combines finished office space with open warehouse area for light distribution and contractor operations.

    3792 Ladson Suite A, Ladson, SC 29456

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    Commercial Retail/Office Space Available
    $18 SF/Yr
    3,000 SF
    Commercial Retail/Office Space Available

    3000 SF commercial space near highway, Sam's Club, Costco.

    735 Saturn Pkwy, Columbia, SC 29212

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    Built-Out Fitness/Office Retail Suite
    Contact for pricing
    Built-Out Fitness/Office Retail Suite

    Existing gym-built suite near Wentworth and King, with adjacent parking garage support for daily foot traffic.

    69 Wentworth Street Unit B, Charleston, SC 29401

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    Irmo Office Space For Rent
    $15,000/Mo
    2,478 SF
    Irmo Office Space For Rent

    Office space available for lease in Irmo, South Carolina.

    10020 Broad River Rd, Irmo, SC

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    Restored Office Space in Charleston
    Contact for pricing
    2,566 SF
    Restored Office Space in Charleston

    Historic office space near Cooper River Waterfront available for rent.

    4 / 8 N Atlantic Wharf #2nd Floor, Charleston, SC 29401

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