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    South Carolina Office Units for Lease

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    Myrtle Beach, SC Greenville, SC Columbia, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Murrells Inlet, SC
    Found 987 office unit listings for lease in South Carolina, averaging $25/SF/YR. Use lease type data to compare options faster.
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    Former Bank Branch with Drive-Thru
    Former Bank Branch with Drive-Thru

    3898 Liberty Highway, Anderson, SC 29621

    $18 SF/Yr

    Former bank branch with drive-thru located near major retailers.

    View details
    Waterfront Office Suite
    Waterfront Office Suite

    75 Port City Lndg, Mt Pleasant, SC 29464

    Class A
    Contact for pricing
    3 private offices  2 meeting rooms

    Class A office space with private offices, conference rooms, a bullpen, break room, and waterfront views.

    Waterfront views  Walking trails  Restaurants
    View details
    Office Space in North Main
    Office Space in North Main

    620 N Main St, Greenville, SC

    Full service
    Contact for pricing
    4–8 people  1 space  1,245 sqft  0.43 acres

    Office space available in North Main, Greenville.

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    Flex Space with Overhead Crane
    Flex Space with Overhead Crane

    1705 Old Georgia Hwy, Gaffney, SC 29341

    Contact for pricing
    32 ft clear  1,600A 3-phase  25 x 50 ft  13,100 sqft office
    Highway access  Rail access  Road access

    Three-building industrial property with warehouse, office, commercial space, heavy power, and truck and trailer parking.

    Utilities to site
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    Office Suite with Parking
    Office Suite with Parking

    111 Lovett Dr, Greenville, SC 29607

    Contact for pricing

    Office suite offered across 1.5 floors with parking and immediate occupancy.

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    Move-in Ready Office Space
    Move-in Ready Office Space

    40 Calhoun St, Charleston, SC 29403

    Full service
    Contact for pricing
    9–16 people  9 spaces  2,481 sqft

    Office space for rent through November 2028.

    View details
    Medical Office Suite
    Medical Office Suite

    548 Nautical Dr Suite 202, Lake Wylie, SC 29710

    Contact for pricing

    The space has a flexible configuration suited to medical and related professional uses.

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    Second-Story Office Unit
    Second-Story Office Unit

    759 Folly Road # C, Charleston, SC 29412

    Crescent
    Contact for pricing
    Built 1980  Floor 2
    3 private offices  Highway access

    Office suite with a reception area, private offices, breakroom, full bathroom, and prominent window exposure.

    10 parking spaces
    View details
    Two-Office Suite with Conference Room
    Two-Office Suite with Conference Room

    2126 Highway 9 E #Suite 2, Longs, SC 29568

    $1,800/Mo
    4–7 people  1,188 sqft
    2 private offices  1 meeting room

    HC-zoned workspace includes a breakroom and the option to rent the neighboring suite for additional office area.

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    Four-Office Marina Office Suite
    Four-Office Marina Office Suite

    668 Marina Drive Ste A2, Charleston, SC 29492

    Daniel Island
    Contact for pricing
    3–6 people  950 sqft
    4 private offices  1 meeting room  Highway access + Road access

    A conference room, shared lounge, and private restroom complement the suite’s four enclosed offices.

    View details
    Retail Suites with Private Patios
    Retail Suites with Private Patios

    1023 Clements Ferry Road, Wando, SC 29492

    Contact for pricing
    Built 2026

    New construction retail and office suites with private outdoor patios at a signalized, high-traffic intersection frontage.

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    Functional Office Spaces For Rent
    Functional Office Spaces For Rent

    2 Park Rd, Hilton Head Island, SC

    Triple net (NNN)
    Contact for pricing
    7–11 people  3 spaces  1,792 sqft  1.82 acres

    Updated building with covered parking and a great location.

    View details
    Multi-Station Office Unit
    Multi-Station Office Unit

    2126 E Highway 9 E #Suite 1, Longs, SC 29568

    $1,800/Mo
    4–7 people  1,188 sqft

    HC-zoned office accommodation includes a waiting area and can be expanded by renting the adjoining unit.

    View details
    Second-Floor Office Unit
    Second-Floor Office Unit

    1991 Glenns Bay Rd., Myrtle Beach, SC 29575

    $1,800/Mo
    6–10 people  1,533 sqft  Built 2000  Floor 2
    Highway access

    New carpeting refreshes the second-floor workspace, available with a minimum one-year lease term.

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    Office Unit with Conference Rooms
    Office Unit with Conference Rooms

    1435 Cannon Rd., Myrtle Beach, SC 29577

    $3,003/Mo
    10–18 people  2,722 sqft  Built 1997
    5 private offices  2 meeting rooms  Highway access

    A built-out workspace combines private offices, meeting rooms, reception space, and rear access.

    21 parking spaces
    View details
    Mount Pleasant Office Space Available
    Mount Pleasant Office Space Available

    1041 Johnnie Dodds Blvd, Mount Pleasant, SC

    Contact for pricing
    6–10 people  1 space  1,600 sqft  0.5 acres

    Office space featuring private offices, conference area, and kitchen.

    View details
    Move-In Ready Office Space
    Move-In Ready Office Space

    12 Maple Tree Ct, Greenville, SC 29615

    Contact for pricing
    10–17 people  2,578 sqft
    Highway access

    Office space with excellent visibility from Pelham Road and ample parking near I-85.

    Monument Signage Available on Pelham Road
    View details
    Medical Office Space with New Roof
    Medical Office Space with New Roof

    90 Brighton Hill Rd, Columbia, SC 29223

    Triple net (NNN)
    Contact for pricing
    6,564 sqft  1.75 acres
    GC

    Flexible medical office space on a substantial commercial parcel with GC zoning and updated building systems.

    View details
    Furnished Office Unit
    Furnished Office Unit

    10 Accountants Circle, Seneca, SC 29678

    Contact for pricing

    Professional suite with nearby restroom, break room access, parking, and optional office furnishings.

    Furnished  Restroom access  Break room
    View details
    Private Office Unit
    Private Office Unit

    106 Earle St, Clemson, SC 29631

    Contact for pricing

    Two work areas, storage, a private bathroom, and utilities support flexible day-to-day operations.

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    Medical/Professional Office Space Available
    Medical/Professional Office Space Available

    235 S. Herlong Avenue, Rock Hill, SC 29732

    Contact for pricing
    1,200 sqft

    Office space with frontage near Piedmont Medical Center.

    View details
    Three-Office Professional Suite
    Three-Office Professional Suite

    600 N Azalea Dr., Surfside Beach, SC 29575

    $1,400/Mo
    4–6 people  1,000 sqft  Built 1984
    3 private offices

    A single-level plan pairs a reception area with three separate offices and a bathroom.

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    Columbia Office Space For Lease
    Columbia Office Space For Lease

    1370 Browning Rd, Columbia, SC

    Full service
    Contact for pricing
    10–18 people  1 space  2,722 sqft  1.67 acres

    Office suites available in desirable Columbia suburban submarket.

    View details
    Office Space with Ample Parking
    Office Space with Ample Parking

    1200 Brookfield Parkway, Greenville, SC 29607

    $15 SF/Yr

    Office space for rent with easy interstate access and parking.

    View details
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