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    South Carolina Office Units for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    Showing 24 of 1,028 listings
    Office Space Available for Lease
    $15 SF/Yr
    Office Space Available for Lease

    Office space available for lease in Anderson, SC.

    309 E Greenville St, Anderson, SC 29621

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    Downtown Greenville Corner Retail Space
    Contact for pricing
    5,700 SF
    Downtown Greenville Corner Retail Space

    Class A retail/office space in prime downtown Greenville location.

    106 W Washington St, Greenville, SC 29601

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    Updated Mixed-Use Commercial Space
    Contact for pricing
    2,201 SF
    Updated Mixed-Use Commercial Space

    Updated mixed-use space with parking and high-speed internet in Columbia.

    746 Harden St., Columbia, SC 29205

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    Prime Office Space in Greenville
    $750/Mo
    4,658 SF
    Prime Office Space in Greenville

    High-end office space near downtown Greenville and Reedy River Falls.

    1 Augusta St, Greenville, SC

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    Mt. Pleasant Office/Medical Space
    $12 SF/Yr
    6,185 SF
    Mt. Pleasant Office/Medical Space

    Office and medical suites available in Mt. Pleasant location.

    900 Bowman Rd, Mt Pleasant, SC

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    Second Floor Office Space Available
    $650/Mo
    400 SF
    Second Floor Office Space Available

    400 SF office space available 10/1/2025 in Murrells Inlet.

    627 Bellamy Ave, Murrells Inlet, SC

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    Eco-Friendly Office Park Suite
    Contact for pricing
    3,264 SF
    Eco-Friendly Office Park Suite

    Office suites available in a four-building park with eco-friendly design and flexible space sizes.

    3417 Maybank Highway, Johns Island, SC 29455

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    Office Space in Greenville, SC
    $1,250/Mo
    1,915 SF
    Office Space in Greenville, SC

    Office space for sublease featuring a bright, open layout.

    105 Pelham Co, Greenville, SC 29615

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    Downtown Spartanburg Office Space
    $16 SF/Yr
    1,395 SF
    Downtown Spartanburg Office Space

    Office space in downtown Spartanburg with professional finishes.

    275 E Henry St, Spartanburg, SC

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    Class A Office Suite
    $23 SF/Yr
    2,268 SF
    Class A Office Suite

    Available office suite in Spartanburg's Point West Office Complex.

    775 Spartan Blvd, Spartanburg, SC

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    Westside Office/Medical Space Available
    $16 SF/Yr
    5,461 SF
    Westside Office/Medical Space Available

    5461± sq ft office/medical space for rent.

    225 E Blackstock Rd, Spartanburg, SC

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    6,000 SF Flex Building I-85
    Contact for pricing
    6,000 SF
    6,000 SF Flex Building I-85

    Flex building with lay-down yard fronting I-85.

    50 Fairview Church Rd, Spartanburg, SC 29303

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    Commercial Building Near Sea Pines
    Contact for pricing
    22,082 SF
    Commercial Building Near Sea Pines

    Freestanding commercial building with showroom, office, and warehouse space.

    10 Target Road, Hilton Head Island, SC 29928

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    Office Space For Lease
    $15 SF/Yr
    2,400 SF
    Office Space For Lease

    Office space available for lease near Boiling Springs and Lake Bowen.

    7770 Hwy 9, Inman, SC

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    Downtown Fountain Inn Flexible Space
    Contact for pricing
    3,500 SF
    Downtown Fountain Inn Flexible Space

    Flexible commercial space in downtown Fountain Inn, ideal for various uses.

    116 N Main St., Fountain Inn, SC 29644

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    Retail/Office Space Near I-77
    $20 SF/Yr
    20,790 SF
    Retail/Office Space Near I-77

    High-visibility retail/office space near Manchester Meadows and I-77.

    247 E. Mt. Gallant Road, Rock Hill, SC 29730

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    Former Bank Branch with Drive-Thru
    $18 SF/Yr
    Former Bank Branch with Drive-Thru

    Former bank branch with drive-thru located near major retailers.

    3898 Liberty Highway, Anderson, SC 29621

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    Industrial Flex Warehouse Space Available
    Contact for pricing
    5,000 SF
    Industrial Flex Warehouse Space Available

    Industrial flex warehouse space for lease, available June 1, 2026.

    390 Railroad Avenue, Lexington, SC 29072

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    Daniel Island Office Space Available
    $25 SF/Yr
    2,300 SF
    Daniel Island Office Space Available

    2,300 SF office space for lease on Daniel Island.

    234 Seven Farms Dr, Daniel Island, SC

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    Individual Offices For Sublease
    $600/Mo
    Individual Offices For Sublease

    Two individual offices for sublease near Pelham Rd and I-85.

    153 Brozzini Ct, Greenville, SC

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    Class A Office Space
    Contact for pricing
    1,523 SF
    Class A Office Space

    Office space for lease in North Charleston, South Carolina.

    1940 Algonquin Rd, North Charleston, SC 29405

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    Updated Office Space For Rent
    $18 SF/Yr
    4,086 SF
    Updated Office Space For Rent

    Office space with updated finishes and private offices available.

    7640-7660 Pelham Rd, Greenville, SC

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    Downtown Office Space Available
    $35 SF/Yr
    5,667 SF
    Downtown Office Space Available

    Office suite for lease in downtown location with modern amenities.

    116-120 N Markley St, Greenville, SC

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    Professional Office Building For Lease
    $20 SF/Yr
    1,299 SF
    Professional Office Building For Lease

    Professional office building in Murrells Inlet with customizable units.

    4717 Hwy 17, Murrells Inlet, SC

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