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    South Portland, ME Office Units for Lease

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    Portland, ME Bangor, ME Lewiston, ME
    25 results
    Office Space in John Roberts
    $15 SF/Yr
    10,000 SF

    Office Space in John Roberts

    9 Donald B Dean Dr, South Portland, ME

    Class A office space available for rent in South Portland.

    • Class A office space.
    • 10,000± SF available or subdividable.
    • In close proximity to the Maine Mall & I‑295.
    • Prominent building with great visibility.
    • Located in John Roberts Office Park.
    Updated: Nov 10, 2025
    View details
    Class-A Office Suite For Lease
    $16 SF/Yr
    5,121 SF

    Class-A Office Suite For Lease

    30 Long Creek Dr, South Portland, ME

    Full-floor office suite in South Portland's Maine Mall area.

    • Full‑floor, Class‑A office suite in a prime location within South Portland's Maine Mall area.
    • Turn‑key, high‑quality office environment ready for immediate occupancy.
    • 5,121± SF of space featuring 13 offices, meeting spaces, and collaborative open space.
    • Abundant natural light throughout the suite.
    • Includes a kitchenette and two dedicated restrooms.
    Updated: Jul 7, 2025
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    South Portland Office Space Available
    $16 SF/Yr
    6,321 SF

    South Portland Office Space Available

    Office space for lease near Maine Mall and Portland Jetport.

    311 Darling Ave, South Portland, ME
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    South Portland Retail/Office Opportunity
    Contact for pricing
    11,890 SF

    South Portland Retail/Office Opportunity

    Modern, adaptable space in high-traffic Maine Mall area.

    264 Gorham Rd, South Portland, ME
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    Class A Office Sublease Available
    $15 SF/Yr
    7,599 SF

    Class A Office Sublease Available

    7,599±SF Class A office space for sublease in South Portland.

    500 Southborough Dr, South Portland, ME
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    Industrial Facility with Modern Office
    Contact for pricing
    10,654 SF

    Industrial Facility with Modern Office

    Well-maintained industrial and office space near I-95 and Jetport.

    76 Darling Ave, South Portland, ME 4106
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    South Portland Office Space Available
    Contact for pricing
    2,601 SF

    South Portland Office Space Available

    Class A office space for lease near I-95 and I-295.

    324 Cummings Rd, South Portland, ME
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    Corner Office Suite For Rent
    $14 SF/Yr
    4,040 SF

    Corner Office Suite For Rent

    4,040± SF office suite with ample free parking.

    202 Gannett Dr, South Portland, ME
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    Class A Office Suite Available
    $13 SF/Yr
    3,765 SF

    Class A Office Suite Available

    3,765 SF office suite for lease in South Portland.

    82 Running Hill Road, South Portland, ME 4106
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    South Portland Office Space Available
    $10 SF/Yr
    1,812 SF

    South Portland Office Space Available

    Office space for lease in landmark South Portland building.

    100 Brickhill Avenue, South Portland, ME
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    South Portland Office Space Available
    $13 SF/Yr
    2,500 SF

    South Portland Office Space Available

    2,500± SF office space for lease in South Portland.

    141 Main St, South Portland, ME
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    South Portland Warehouse and Office
    $10 SF/Yr
    31,360 SF

    South Portland Warehouse and Office

    Warehouse and office space for lease in South Portland.

    1 Madison Street, South Portland, ME 4101
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    South Portland Office Space Available
    $14 SF/Yr
    11,162 SF

    South Portland Office Space Available

    Office space for lease in South Portland with ample parking.

    600 Sable Oaks Dr, South Portland, ME 4106
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    Class A Office Space Available
    $15 SF/Yr
    36,703 SF

    Class A Office Space Available

    Class A office space for lease near major transportation routes.

    179 John Roberts Rd, South Portland, ME 4106
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    Class A Office Space Available
    Contact for pricing
    8,532 SF

    Class A Office Space Available

    Premier office park with modern finishes and convenient location.

    600 Southborough Dr, South Portland, ME 4106
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    Retail/Office Space Near Maine Mall
    Contact for pricing
    1,700 SF

    Retail/Office Space Near Maine Mall

    1,700± SF retail/office space with convenient highway access.

    209 Western Ave, South Portland, ME 4106
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    South Portland Warehouse and Office
    Contact for pricing
    31,630 SF

    South Portland Warehouse and Office

    Warehouse and office space for lease in South Portland.

    1 Madison St, South Portland, ME 4106
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    Suburban Office Park Sublease Opportunity
    Contact for pricing
    16,912 SF

    Suburban Office Park Sublease Opportunity

    Office space for sublease in premier suburban office park.

    78 Atlantic Pl, South Portland, ME 4106
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    Office Space Near Portland Jetport
    Contact for pricing

    Office Space Near Portland Jetport

    Office space for rent near the Portland Jetport.

    179 John Roberts Rd, South Portland, ME 4106
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    South Portland Office Space Available
    Contact for pricing
    6,321 SF

    South Portland Office Space Available

    Office suites for lease in premier suburban office park.

    311 Darling Ave, South Portland, ME 4106
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    South Portland Class A Office
    $15 SF/Yr
    8,114 SF

    South Portland Class A Office

    Class A office and flex space in South Portland for lease.

    75 John Roberts Rd, South Portland, ME 4106
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    South Portland Office Space Available
    Contact for pricing
    11,162 SF

    South Portland Office Space Available

    Office space for rent in South Portland with ample parking.

    600 Sable Oaks Dr, South Portland, ME 4106
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    Renovated Office Space Available
    Contact for pricing
    14,400 SF

    Renovated Office Space Available

    Fully renovated office space for lease in South Portland.

    1 Runway Road, South Portland, ME 4106
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    Class A Office Space Available
    $15 SF/Yr
    8,532 SF

    Class A Office Space Available

    Class A office space for lease in South Portland, Maine.

    600 Southborough Dr, South Portland, ME 4106
    View details

    South Portland, ME Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in South Portland, ME with 25 listings featured on our commercial real estate exchange. The current inventory includes 141,363 square feet of properties with an estimated lease value of $206 SF/Yr.

    Estimated lease rates for Office Units in South Portland, ME begin at $10 SF/Yr, with an average of $14 SF/Yr and extend to $23 SF/Yr.
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    Most Searched ZIP Codes in South Portland, ME

    • 04106
    • 04101

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