Lancaster, SC Office Spaces for sale

Updated: Sep 8

Commercial Land with Office Building

731 S Market Street, Lancaster, SC 29720

$140,000

1.62 AC lot

1.62‑acre commercial parcel
B3 General Business zoning
Existing office building positioned along the edge of the lot
Approximately 270 feet of frontage on S Market Street
Public water and sewer on site

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Updated: Dec 1, 2025

Two-Building Office Property

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000

0.82 AC lot

Two professional office buildings on a 0.82‑acre property
First building has about 14 rooms and wiring for an X‑ray room
Second building includes three curtained areas and a large open area
New flooring and a new roof in the first building
PO, Professional Office zoning per the City of Lancaster

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Historic Mixed-Use Retail/Office Buildings

209-227 S. Main Street, Lancaster, SC 29720

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29,151 sqft

Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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Downtown Mixed-Use Redevelopment Property

210 S. White Street, Lancaster, SC 29720

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22,251 sqft

Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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Office Building

312 N Main Street N, Lancaster, SC 29720

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2,706 sqft

Office building with some furnishings staying, and utility split where tenant pays electricity and natural gas.

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1930s Retail/Office Building Portfolio

116 Arch Street, Lancaster, SC 29720

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29,444 sqft

Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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Medical Office Buildings Near MUSC

1201 Colonial Commons Ct, Lancaster, SC 29720

$975,000

Two professional buildings suitable for medical or office use.

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Versatile Commercial Building in Lancaster

302 N White St, Lancaster, SC 29720

$325,000

Two-story commercial building with offices in downtown Lancaster, SC.

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Office Building with Live-Work Use

36-305 E Arch St, Lancaster, SC 29720

$250,000

B-2 zoning supports residential occupancy alongside a business, with parking and accessible entry.

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Commercial Land with Office Building

731 S Market St, Lancaster, SC 29720

$140,000

B3-zoned parcel with an existing office building and city utilities on site.

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Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 10 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 62 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Corner-Lot Flex Space with Bay Door

215 Dearborn St, Great Falls, SC 29055

$299,000

4,800 sqft 0.69 AC lot

Three separately configured areas combine offices, reception rooms, and workshop space.

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Two-Building Office Property

320 Dearborn St, Great Falls, SC 29055

$110,000

1,449 sqft

Two separate structures provide reception, office, storage, and support areas for flexible business use.

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Former Medical Office Space

110 South Cleveland Street, Kershaw, SC 29067

$150,000

3,550 sqft

3,350 SF medical office with 11 parking spaces.

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Medical Office Building

104 S Ashe Street, Kershaw, SC 29067

$200,000

1.76 AC lot

Electric heating and air conditioning serve this office property within Kershaw’s town limits.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Brick Storefront Property

2836 Lynwood Drive, Lancaster, SC 29720

$149,900

0.47 AC lot

Commercial space with central air, electric heat, carpet flooring, and a bathroom.

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Light Industrial Land For Sale

00 Fork Hill Road, Kershaw, SC 29067

$90,000

Land zoned for light industrial use with possible residential rezoning.

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Commercial Land with Dual Frontage

2164 Eden Terrace, Rock Hill, SC 29730

$350,000

3.64 AC lot

GC-zoned development site with public sewer and access from two road frontages.

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O-I Zoned Commercial Land

2135 Eden Terrace, Rock Hill, SC 29730

$450,000

1.08 AC lot

The parcel is zoned O-I and has public sewer service for commercial land planning.

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Off-Market Properties in Lancaster, SC

Consider similar Off-Market properties in Lancaster, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.