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    Lancaster, SC Office Properties & Spaces for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    6 results
    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres

    Two Professional Buildings Near MUSC

    1201 Colonial Commons Court, Lancaster, SC 29720

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    • Prime location minutes from MUSC (Medical University of South Carolina).
    • Two professional office buildings on one property.
    • Zoned "PO" Professional Office by the City of Lancaster.
    • Building 1 features a medical office layout with 14 rooms and a wired X‑ray room.
    • New flooring and new roof installed in Building 1.
    Updated: Dec 1, 2025
    View details
    Versatile Commercial Building in Lancaster
    $349,000

    Versatile Commercial Building in Lancaster

    302 N White St, Lancaster, SC 29720

    Two-story commercial building with offices in downtown Lancaster, SC.

    • Prime location in the heart of downtown Lancaster's growing business district.
    • Versatile commercial building suitable for multiple businesses or a single expanding operation.
    • Two floors, each with four offices and a half bath.
    • Total of 16 rooms and four half baths.
    • Excellent accessibility for clients and employees.
    Updated: Mar 13
    View details
    Medical Office Buildings Near MUSC
    $975,000

    Medical Office Buildings Near MUSC

    Two professional buildings suitable for medical or office use.

    1201 Colonial Commons Ct, Lancaster, SC 29720
    View details
    Mixed-Use Commercial Property For Sale
    $450,000

    Mixed-Use Commercial Property For Sale

    Four buildings with six potential rental opportunities on 1.6 acres.

    2415 Pineview Drive, Lancaster, SC 29720
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    Lancaster Light Industrial Facility
    $299,000
    3,400 SF

    Lancaster Light Industrial Facility

    3,400 SF facility on 2 acres near Rock Hill.

    1537 Lynwood Drive, Lancaster, SC 29720
    View details
    Lancaster Medical/Office Space Available
    $875,000
    6,900 SF

    Lancaster Medical/Office Space Available

    Versatile space near MUSC Health Lancaster Medical Center.

    980 N Woodland Dr, Lancaster, SC
    View details
    Based on your search, we've compiled 192 Potential Opportunities for your consideration. Besides 6 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 178 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Commercial Property with Four Buildings
    $680,000
    8,165 SF

    Commercial Property with Four Buildings

    Commercial/industrial property featuring four buildings on 0.92 acres.

    960, 962 & 966 E. Black Street and 220 Workman St, Rock Hill, SC 29730
    View details
    Rock Hill Warehouse Sublease Opportunity
    Contact for pricing
    54,500 SF

    Rock Hill Warehouse Sublease Opportunity

    Warehouse sublease in Rock Hill's TechPark Business Park.

    467 Lakeshore Pkwy, Rock Hill, SC 29730
    View details
    Office Space Available For Sale
    $384,156
    1,250 SF

    Office Space Available For Sale

    Office property with 1250 square feet of space.

    17232 Lancaster Hwy, Charlotte, NC
    View details
    South Charlotte Office Condo Park
    $384,156
    1,250 SF

    South Charlotte Office Condo Park

    Multi-tenant office condo park in South Charlotte for sale.

    17232 Lancaster Hwy., Charlotte, NC 28277
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Development Land on Charlotte Highway

    Development opportunity on a high-traffic corridor near residential developments.

    2383 Charlotte Highway, Lancaster, SC 29720
    View details
    Prime Development Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Development Land on Charlotte Highway

    15.55 acres with high traffic, development potential.

    2383 Charlotte Highway, Lancaster, SC 29720
    View details
    Commercial Land in Pageland, SC
    $495,000
    1.91 Acres

    Commercial Land in Pageland, SC

    Two parcels totaling 1.91 acres zoned for commercial and residential use.

    605 E Mcgregor Street, Pageland, SC 29728
    View details
    Prime Development Land in Pageland
    $255,000
    2.69 Acres

    Prime Development Land in Pageland

    2.6+/- acre development site on high-traffic corridor in Pageland.

    510 Van Lingle Mungo Boulevard, Pageland, SC 29728
    View details

    Explore Off-Market Properties in Lancaster, SC

    Consider similar Off-Market properties in Lancaster, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    979 University Dr

    979 University Dr

    OFFICE (GENERAL) • 1,584 SF
    Value Estimation by Request
    979 University Dr, Lancaster, SC 29720
    View details
    713 Main St

    713 Main St

    OFFICE (GENERAL) • 1,128 SF
    Value Estimation by Request
    713 Main St, Lancaster, SC 29720-3644
    View details
    312 Miller St

    312 Miller St

    OFFICE (GENERAL) • 1,467 SF
    Value Estimation by Request
    312 Miller St, Lancaster, SC 29720
    View details
    Hwy 914

    Hwy 914

    OFFICE (GENERAL) • 2,586 SF
    Value Estimation by Request
    Hwy 914, Lancaster, SC 29720
    View details
    503 Meeting St

    503 Meeting St

    OFFICE (GENERAL) • 1,210 SF
    Value Estimation by Request
    503 Meeting St, Lancaster, SC 29720-2323
    View details
    1320 Hwy 9th W Byp

    1320 Hwy 9th W Byp

    MEDICAL BUILDING • 1,320 SF
    Value Estimation by Request
    1320 Hwy 9th W Byp, Lancaster, SC 29720-4712
    View details
    312 Main St

    312 Main St

    OFFICE (GENERAL) • 5,644 SF
    Value Estimation
    $535,000
    312 Main St, Lancaster, SC 29720-2132
    View details
    2583 Kershaw Camden Hwy

    2583 Kershaw Camden Hwy

    OFFICE (GENERAL) • 8,060 SF
    Value Estimation by Request
    2583 Kershaw Camden Hwy, Lancaster, SC 29720-6855
    View details
    1104 Lockwood Ln

    1104 Lockwood Ln

    OFFICE (GENERAL) • 2,240 SF
    Value Estimation by Request
    1104 Lockwood Ln, Lancaster, SC 29720-6217
    View details
    Catawba St

    Catawba St

    OFFICE (GENERAL) • 3,128 SF
    Value Estimation by Request
    Catawba St, Lancaster, SC 29720
    View details
    419 Meeting St

    419 Meeting St

    MEDICAL BUILDING • 4,600 SF
    Value Estimation
    $750,000
    419 Meeting St, Lancaster, SC 29720-2321
    View details
    1091 Rebound Rd

    1091 Rebound Rd

    OFFICE (GENERAL) • 1,994 SF
    Value Estimation by Request
    1091 Rebound Rd, Lancaster, SC 29720
    View details
    1629 Springdale Rd

    1629 Springdale Rd

    OFFICE (GENERAL) • 952 SF
    Value Estimation by Request
    1629 Springdale Rd, Lancaster, SC 29720-2253
    View details
    Brick Yard Dr

    Brick Yard Dr

    OFFICE (GENERAL) • 4,572 SF
    Value Estimation
    $2,025,000
    Brick Yard Dr, Lancaster, SC 29720
    View details
    208 Gay St

    208 Gay St

    OFFICE (GENERAL) • 2,500 SF
    Value Estimation by Request
    208 Gay St, Lancaster, SC 29720-2424
    View details
    Memorial Park Rd

    Memorial Park Rd

    OFFICE (GENERAL) • 1,604 SF
    Value Estimation by Request
    Memorial Park Rd, Lancaster, SC 29720
    View details
    136 Grace Ave

    136 Grace Ave

    OFFICE (GENERAL) • 77,662 SF
    Value Estimation by Request
    136 Grace Ave, Lancaster, SC 29720-4266
    View details
    5222 Old Hickory Rd

    5222 Old Hickory Rd

    OFFICE (GENERAL) • 1,327 SF
    Value Estimation by Request
    5222 Old Hickory Rd, Lancaster, SC 29720-0320
    View details

    Lancaster, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 184 office properties & spaces for sale in Lancaster, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 310,950,107 square feet of properties for sale, with an estimated market value of $38,125,000.

    Sale prices for office spaces in Lancaster, SC start at $55,000, averaging $377,475, and reaching up to $6,550,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Office properties & Spaces for Sale Near Lancaster, SC

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    Most Searched ZIP Codes in Lancaster, SC

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