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    Lancaster, SC Office Spaces for Sale

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    Fort Lawn, SC Heath Springs, SC Waxhaw, NC
    6 results
    Lancaster Commercial Building For Sale
    $139,999
    0.12 Acres
    Lancaster Commercial Building For Sale

    401 E Gay Street, Lancaster, SC 29720

    Commercial building in growing area with business or investment potential.
    • Excellent visibility and accessibility in a growing area
    • Ideal for business, office, retail, or investment
    • Parking lot included
    • Ready for new ownership and fresh ideas
    • Investment potential
    Updated: May 15
    View details
    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres
    Two Professional Buildings Near MUSC

    1201 Colonial Commons Court, Lancaster, SC 29720

    Two professional office buildings near MUSC in Lancaster, South Carolina.
    • Prime location minutes from MUSC (Medical University of South Carolina).
    • Two professional office buildings on one property.
    • Zoned "PO" Professional Office by the City of Lancaster.
    • Building 1 features a medical office layout with 14 rooms and a wired X‑ray room.
    • New flooring and new roof installed in Building 1.
    Updated: Dec 1, 2025
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    Versatile Commercial Building in Lancaster
    $349,000
    Versatile Commercial Building in Lancaster

    Two-story commercial building with offices in downtown Lancaster, SC.

    302 N White St, Lancaster, SC 29720

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    Medical Office Buildings Near MUSC
    $975,000
    Medical Office Buildings Near MUSC

    Two professional buildings suitable for medical or office use.

    1201 Colonial Commons Ct, Lancaster, SC 29720

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    Commercial Property for Sale
    $149,900
    1,248 SF
    Commercial Property for Sale

    Commercial property suitable for office, retail, or salon.

    2836 Lynwood Drive, Lancaster, SC 29720

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    Lancaster Medical/Office Space Available
    $875,000
    6,900 SF
    Lancaster Medical/Office Space Available

    Versatile space near MUSC Health Lancaster Medical Center.

    980 N Woodland Dr, Lancaster, SC

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 6 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 66 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Kershaw Office Building on Large Lot
    $200,000
    1,100 SF
    Kershaw Office Building on Large Lot

    Office building on 1.76 acres in Kershaw, South Carolina.

    104 S Ashe Street, Kershaw, SC 29067

    View details
    Former Medical Office Space
    $150,000
    3,550 SF
    Former Medical Office Space

    3,350 SF medical office with 11 parking spaces.

    110 South Cleveland Street, Kershaw, SC 29067

    View details
    Rock Hill Warehouse Sublease Opportunity
    Contact for pricing
    54,500 SF
    Rock Hill Warehouse Sublease Opportunity

    Warehouse sublease in Rock Hill's TechPark Business Park.

    467 Lakeshore Pkwy, Rock Hill, SC 29730

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    Commercial Property with Four Buildings
    $680,000
    8,165 SF
    Commercial Property with Four Buildings

    Commercial/industrial property featuring four buildings on 0.92 acres.

    960, 962 & 966 E. Black Street and 220 Workman St, Rock Hill, SC 29730

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Lancaster, SC
    $149,900
    0.47 Acres
    Commercial Land in Lancaster, SC

    Commercial land suitable for various business ventures.

    2836 Lynwood Drive, Lancaster, SC 29720

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    Light Industrial Land For Sale
    $90,000
    Light Industrial Land For Sale

    Land zoned for light industrial use with possible residential rezoning.

    00 Fork Hill Road, Kershaw, SC 29067

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    Commercial Lot in Rock Hill
    $450,000
    1.08 Acres
    Commercial Lot in Rock Hill

    Commercial land for sale, suitable for development or owner financing.

    2135 Eden Terrace, Rock Hill, SC 29730

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    Rock Hill Commercial Land Available
    $350,000
    3.64 Acres
    Rock Hill Commercial Land Available

    3.64 acre commercial land parcel in Rock Hill, SC.

    2164 Eden Terrace, Rock Hill, SC 29730

    View details

    Off-Market Properties in Lancaster, SC

    Consider similar Off-Market properties in Lancaster, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    979 University Dr
    OFFICE (GENERAL)
    1,584 SF Lot: 130.00 Acres
    Value Estimation by Request

    979 University Dr, Lancaster, SC 29720

    View details
    713 Main St
    OFFICE (GENERAL)
    1,128 SF Lot: 234.00 Acres
    Value Estimation by Request

    713 Main St, Lancaster, SC 29720-3644

    View details
    312 Miller St
    OFFICE (GENERAL)
    1,467 SF Lot: 4.40 Acres
    Value Estimation by Request

    312 Miller St, Lancaster, SC 29720

    View details
    Hwy 914
    OFFICE (GENERAL)
    2,586 SF Lot: 200.00 Acres
    Value Estimation by Request

    Hwy 914, Lancaster, SC 29720

    View details
    503 Meeting St
    OFFICE (GENERAL)
    1,210 SF Lot: 75.00 Acres
    Value Estimation by Request

    503 Meeting St, Lancaster, SC 29720-2323

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    1320 Hwy 9th W Byp
    MEDICAL BUILDING
    1,320 SF Lot: 70.00 Acres
    Value Estimation by Request

    1320 Hwy 9th W Byp, Lancaster, SC 29720-4712

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    312 Main St
    OFFICE (GENERAL)
    5,644 SF Lot: 130.00 Acres
    Estimated value
    $535,000

    312 Main St, Lancaster, SC 29720-2132

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    2583 Kershaw Camden Hwy
    OFFICE (GENERAL)
    8,060 SF Lot: 0.67 Acres
    Value Estimation by Request

    2583 Kershaw Camden Hwy, Lancaster, SC 29720-6855

    View details
    1104 Lockwood Ln
    OFFICE (GENERAL)
    2,240 SF Lot: 283.00 Acres
    Value Estimation by Request

    1104 Lockwood Ln, Lancaster, SC 29720-6217

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    Catawba St
    OFFICE (GENERAL)
    3,128 SF Lot: 100.00 Acres
    Value Estimation by Request

    Catawba St, Lancaster, SC 29720

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    419 Meeting St
    MEDICAL BUILDING
    4,600 SF Lot: 22.00 Acres
    Estimated value
    $750,000

    419 Meeting St, Lancaster, SC 29720-2321

    View details
    1091 Rebound Rd
    OFFICE (GENERAL)
    1,994 SF Lot: 22.73 Acres
    Value Estimation by Request

    1091 Rebound Rd, Lancaster, SC 29720

    View details
    1629 Springdale Rd
    OFFICE (GENERAL)
    952 SF Lot: 180.00 Acres
    Value Estimation by Request

    1629 Springdale Rd, Lancaster, SC 29720-2253

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    Brick Yard Dr
    OFFICE (GENERAL)
    4,572 SF Lot: 48.63 Acres
    Estimated value
    $2,025,000

    Brick Yard Dr, Lancaster, SC 29720

    View details
    208 Gay St
    OFFICE (GENERAL)
    2,500 SF Lot: 130.00 Acres
    Value Estimation by Request

    208 Gay St, Lancaster, SC 29720-2424

    View details
    Memorial Park Rd
    OFFICE (GENERAL)
    1,604 SF Lot: 6.28 Acres
    Value Estimation by Request

    Memorial Park Rd, Lancaster, SC 29720

    View details
    136 Grace Ave
    OFFICE (GENERAL)
    77,662 SF Lot: 22.60 Acres
    Value Estimation by Request

    136 Grace Ave, Lancaster, SC 29720-4266

    View details
    5222 Old Hickory Rd
    OFFICE (GENERAL)
    1,327 SF Lot: 1.44 Acres
    Value Estimation by Request

    5222 Old Hickory Rd, Lancaster, SC 29720-0320

    View details

    Lancaster, SC Office Spaces Investment Opportunities Market Analysis

    Explore 72 office spaces for sale in Lancaster, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 8,148 square feet of properties for sale, with an estimated market value of $1,024,900.

    Sale prices for office spaces in Lancaster, SC start at $149,900, averaging $512,450, and reaching up to $875,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 5
    Medical Office Space 3
    Office buildings 2

    Demographics Overview

    Population 52K
    Population Growth (5Y) +8.0%
    Median Household Income $59,039
    College Educated 9.5%

    High-Yield Neighborhoods for Investment

    Identify Lancaster submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    29720 $517.8K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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