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    Lancaster, SC Office Spaces for Sale

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    Fort Lawn, SC Waxhaw, NC Heath Springs, SC Catawba, SC Richburg, SC Edgemoor, SC Great Falls, SC Monroe, NC
    7 properties
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    Two-Building Professional Office Property
    Updated: Dec 1, 2025
    Two-Building Professional Office Property

    1201 Colonial Commons Court, Lancaster, SC 29720

    $975,000
    0.82 AC lot
    Two professional buildings on one property: 1201 and 1203 Colonial Commons Ct
    1201 Colonial Commons Ct set up as a medical office with ~14 rooms, reception, waiting room, and wired for an X‑ray room
    1203 Colonial Commons Ct includes reception and waiting room areas, file room, three curtained areas, large open space, and upper‑level work stations
    PO (Professional Office) zoning per the City of Lancaster zoning chart
    Building 1 received new flooring and a new roof
    View details
    Historic Mixed-Use Retail/Office Buildings
    Updated: Jun 11
    Historic Mixed-Use Retail/Office Buildings

    209-227 S. Main Street, Lancaster, SC 29720

    $575,000
    29,151 sqft
    1930s‑vintage commercial buildings in downtown Lancaster, SC, historically used for retail or office space
    Currently vacant and in need of renovation—space offers a value‑add rehabilitation opportunity
    Off Highway 521 and about 5 minutes from the Highway 9 intersection
    Within 10 miles: population of over 56,000 grew 10% since 2020, with a forecast to grow an additional 16% by 2029
    More than $641 million in consumer spending during 2024 within 10 miles
    View details
    Downtown Mixed-Use Redevelopment Property
    Downtown Mixed-Use Redevelopment Property

    210 S. White Street, Lancaster, SC 29720

    $760,000
    22,251 sqft

    Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    1930s Retail/Office Building Portfolio
    1930s Retail/Office Building Portfolio

    116 Arch Street, Lancaster, SC 29720

    $575,000
    29,444 sqft

    Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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    Downtown Mixed-Use Building for Renovation
    Downtown Mixed-Use Building for Renovation

    229 S. Main Street, Lancaster, SC 29720

    $275,000
    15,266 sqft

    Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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    Medical Office Buildings Near MUSC
    Medical Office Buildings Near MUSC

    1201 Colonial Commons Ct, Lancaster, SC 29720

    $975,000

    Two professional buildings suitable for medical or office use.

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    Versatile Commercial Building in Lancaster
    Versatile Commercial Building in Lancaster

    302 N White St, Lancaster, SC 29720

    $325,000

    Two-story commercial building with offices in downtown Lancaster, SC.

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 7 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 65 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Kershaw Office Building on Large Lot
    Kershaw Office Building on Large Lot

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1,100 sqft 1.76 AC lot

    Office building on 1.76 acres in Kershaw, South Carolina.

    View details
    General Commercial Development Site
    General Commercial Development Site

    1195 Albright Rd, Rock Hill, SC 29730

    $229,000
    7,300 sqft 3.44 AC lot

    Commercial land zoned GC with conceptual plans for a future building and proposed access via easement.

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    Former Medical Office Space
    Former Medical Office Space

    110 South Cleveland Street, Kershaw, SC 29067

    $150,000
    3,550 sqft

    3,350 SF medical office with 11 parking spaces.

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    Rock Hill Office Building For Sale
    Rock Hill Office Building For Sale

    454 Anderson Rd S, Rock Hill, SC

    Contact for pricing
    117,255 sqft 9.29 AC lot

    Four-story office building with value-add potential in Rock Hill.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Lancaster, SC
    Commercial Land in Lancaster, SC

    2836 Lynwood Drive, Lancaster, SC 29720

    $149,900
    0.47 AC lot

    Commercial land suitable for various business ventures.

    View details
    Light Industrial Land For Sale
    Light Industrial Land For Sale

    00 Fork Hill Road, Kershaw, SC 29067

    $90,000

    Land zoned for light industrial use with possible residential rezoning.

    View details
    Rock Hill Commercial Land Available
    Rock Hill Commercial Land Available

    2164 Eden Terrace, Rock Hill, SC 29730

    $350,000
    3.64 AC lot

    3.64 acre commercial land parcel in Rock Hill, SC.

    View details
    Commercial Lot in Rock Hill
    Commercial Lot in Rock Hill

    2135 Eden Terrace, Rock Hill, SC 29730

    $450,000
    1.08 AC lot

    Commercial land for sale, suitable for development or owner financing.

    View details

    Off-Market Properties in Lancaster, SC

    Consider similar Off-Market properties in Lancaster, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    979 University Dr
    OFFICE (GENERAL)

    979 University Dr, Lancaster, SC 29720

    Value Estimation by Request
    1,584 sqft 130.00 AC lot
    View details
    713 Main St
    OFFICE (GENERAL)

    713 Main St, Lancaster, SC 29720-3644

    Value Estimation by Request
    1,128 sqft 234.00 AC lot
    View details
    312 Miller St
    OFFICE (GENERAL)

    312 Miller St, Lancaster, SC 29720

    Value Estimation by Request
    1,467 sqft 4.40 AC lot
    View details
    Hwy 914
    OFFICE (GENERAL)

    Hwy 914, Lancaster, SC 29720

    Value Estimation by Request
    2,586 sqft 200.00 AC lot
    View details
    503 Meeting St
    OFFICE (GENERAL)

    503 Meeting St, Lancaster, SC 29720-2323

    Value Estimation by Request
    1,210 sqft 75.00 AC lot
    View details
    1320 Hwy 9th W Byp
    MEDICAL BUILDING

    1320 Hwy 9th W Byp, Lancaster, SC 29720-4712

    Value Estimation by Request
    1,320 sqft 70.00 AC lot
    View details
    312 Main St
    OFFICE (GENERAL)

    312 Main St, Lancaster, SC 29720-2132

    $535,000
    Estimated value
    5,644 sqft 130.00 AC lot
    View details
    2583 Kershaw Camden Hwy
    OFFICE (GENERAL)

    2583 Kershaw Camden Hwy, Lancaster, SC 29720-6855

    Value Estimation by Request
    8,060 sqft 0.67 AC lot
    View details
    1104 Lockwood Ln
    OFFICE (GENERAL)

    1104 Lockwood Ln, Lancaster, SC 29720-6217

    Value Estimation by Request
    2,240 sqft 283.00 AC lot
    View details
    Catawba St
    OFFICE (GENERAL)

    Catawba St, Lancaster, SC 29720

    Value Estimation by Request
    3,128 sqft 100.00 AC lot
    View details
    419 Meeting St
    MEDICAL BUILDING

    419 Meeting St, Lancaster, SC 29720-2321

    $750,000
    Estimated value
    4,600 sqft 22.00 AC lot
    View details
    1091 Rebound Rd
    OFFICE (GENERAL)

    1091 Rebound Rd, Lancaster, SC 29720

    Value Estimation by Request
    1,994 sqft 22.73 AC lot
    View details
    1629 Springdale Rd
    OFFICE (GENERAL)

    1629 Springdale Rd, Lancaster, SC 29720-2253

    Value Estimation by Request
    952 sqft 180.00 AC lot
    View details
    Brick Yard Dr
    OFFICE (GENERAL)

    Brick Yard Dr, Lancaster, SC 29720

    $2,025,000
    Estimated value
    4,572 sqft 48.63 AC lot
    View details
    208 Gay St
    OFFICE (GENERAL)

    208 Gay St, Lancaster, SC 29720-2424

    Value Estimation by Request
    2,500 sqft 130.00 AC lot
    View details
    Memorial Park Rd
    OFFICE (GENERAL)

    Memorial Park Rd, Lancaster, SC 29720

    Value Estimation by Request
    1,604 sqft 6.28 AC lot
    View details
    136 Grace Ave
    OFFICE (GENERAL)

    136 Grace Ave, Lancaster, SC 29720-4266

    Value Estimation by Request
    77,662 sqft 22.60 AC lot
    View details

    Lancaster, SC Office Spaces Market Trends and Statistics

    Explore 72 office spaces for sale in Lancaster, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 96,112 square feet of properties for sale, with an estimated market value of $2,185,000.

    Sale prices for office spaces in Lancaster, SC start at $275,000, averaging $546,250, and reaching up to $760,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office buildings 6
    Office Units 4
    Medical Office Space 2

    Demographics Overview

    Population 52K
    Population Growth (5Y) +8.0%
    Median Household Income $59,039
    College Educated 9.5%

    High-Yield Neighborhoods for Investment

    Identify Lancaster submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29720 $530.4K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Lancaster County

    New Delisted

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