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Greenwood County, SC Office Spaces for Sale

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Found 10 office space listings for sale in Greenwood County, SC, averaging $98/sq ft. Use valuation data to compare deals faster.
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Corner-Lot Flex Space
Updated: Sep 17, 2025
Corner-Lot Flex Space

1201 E Cambridge Av, Greenwood, SC 29649

$395,000
10,000 sqft 0.80 AC lot
0.8‑acre corner lot in Greenwood, SC
Five roll‑up bay doors serving the warehouse area
Fenced access point for warehouse entry
Concrete‑frame, stucco, and metal construction
Finished areas with tile, carpet, and vinyl flooring
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Brick Flex Space with Industrial Bays
Updated: May 25
Brick Flex Space with Industrial Bays

910 Edgefield Street, Greenwood, SC 29646

$349,000
0.95 AC lot
8,200 SF split‑level commercial building with office and industrial/flex areas
4,100 SF upper level with reception, private offices, conference rooms, storage, and 5 restrooms
4,100 SF lower level with two warehouse/workshop bays and 2 overhead drive‑in doors
Bay sizes of 1,850 SF and 2,250 SF; bays can be occupied together or separately
Fenced 0.25‑acre secure yard with vehicle and equipment washing station
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Flex Building with Warehouse
Flex Building with Warehouse

5108 Old Laurens Rd, Greenwood, SC 29649

$375,000
3,200 sqft 1.08 AC lot

RDD-zoned property combines warehouse, office, storage, and live-work functionality on an expansive commercial parcel.

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Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads
Former Bank with Service Area
Former Bank with Service Area

802 NE By Pass 25, Greenwood, SC 29646

$668,900
5,252 sqft 3.42 AC lot

Former bank building with office space and a rear heated and cooled service area currently used for motorcycle repair.

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Three-Level Mixed-Use Building
Three-Level Mixed-Use Building

202 Main St., Greenwood, SC 29646

$750,000
5,308 sqft

Finished main-level space supports retail, office, or other commercial uses, with additional upper-level and basement areas.

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General Commercial Land
General Commercial Land

1421 E Cambridge Avenue, Greenwood, SC 29646

$350,000
1.80 AC lot

The parcel includes a former residence and water availability for future commercial planning.

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Flex Space with Warehouse Bays
Flex Space with Warehouse Bays

1201 E Cambridge Ave, Greenwood, SC 29649

$395,000
6,000 sqft

Corner-lot commercial building combines finished offices, showroom space, and a fenced access area.

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Office Floors with Live-Work Flexibility
Office Floors with Live-Work Flexibility

327 Main Street, Greenwood, SC 29646

Contact for pricing
1,817 sqft

Own office floors in a historic building with split potential and roof/basement access on the 8th floor.

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Two-Building School Property
Two-Building School Property

1602 Spring St, Greenwood, SC 29646

$1,300,000

Two adjacent buildings offer adaptable layouts for education, administrative, office, medical, and childcare uses.

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Mixed-Use Building with Studio Apartment
Mixed-Use Building with Studio Apartment

204 Main St, Greenwood, SC 29646

$330,000

The two-level layout pairs open commercial space below with a private studio apartment above.

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10 active listings match your search: Office for sale in Greenwood County, SC. Based on your search, we've also compiled 66 Potential Opportunities for your consideration: 62 off-market properties to explore as potential leads and 4 land listings with development potential.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Greenwood Land For Sale
Greenwood Land For Sale

1519 Montague Ave. Ext, Greenwood, SC 29646

$249,900
47,916 sqft 1.10 AC lot

Commercial land with water and sewer access in Greenwood, SC.

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C-2 Commercial Land
C-2 Commercial Land

2611 Hwy 25S, Greenwood, SC 29646

$149,000
1.73 AC lot

C-2-zoned commercial land along Hwy 25S, adjacent to a 120-home residential development.

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C-2 Commercial Land
C-2 Commercial Land

4 acres Hwy 72 Bypass & Hwy 72 Business, Greenwood, SC 29646

$300,000
4.11 AC lot

Commercial land at a signalized intersection with C-2 zoning and utility availability.

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Cleared Commercial Land
Cleared Commercial Land

3308 S Hwy 25, Greenwood, SC 29646

$545,000
3.26 AC lot

C-2-zoned site with public water and gas availability for commercial development.

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Off-Market Properties in Greenwood County, SC

Consider similar Off-Market properties in Greenwood County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

615 Edgefield St
OFFICE BUILDING

615 Edgefield St, Greenwood, SC 29646-3110

Estimated value:
$80,000
1,428 sqft 0.12 AC lot
View details
1815 Montague Ave Ext
MEDICAL BUILDING

1815 Montague Ave Ext, Greenwood, SC 29649-7501

Estimated value:
$425,000
1,922 sqft
View details
1815 Montague Ave Ext
OFFICE BUILDING

1815 Montague Ave Ext, Greenwood, SC 29649-7501

Estimated value:
$230,000
1,929 sqft
View details
1225 Main S St
OFFICE BUILDING

1225 Main S St, Greenwood, SC 29646-3807

Estimated value:
$150,000
2,742 sqft
View details
200 Main N St
OFFICE BUILDING

200 Main N St, Greenwood, SC 29646-2242

Estimated value:
$95,000
2,000 sqft
View details
104 Liner Dr
MEDICAL BUILDING

104 Liner Dr, Greenwood, SC 29646-2310

Estimated value: by Request
7,906 sqft
View details
106 Gregor Mendel Cir
MEDICAL BUILDING

106 Gregor Mendel Cir, Greenwood, SC 29646-2315

Estimated value:
$270,000
View details
101 Gregor Mendel Cir
MEDICAL BUILDING

101 Gregor Mendel Cir, Greenwood, SC 29646-2316

Estimated value:
$360,000
29.81 AC lot
View details
109 Bailey St
OFFICE BUILDING

109 Bailey St, Greenwood, SC 29649

Estimated value:
$115,000
1,966 sqft
View details
210 Montague Ave
OFFICE BUILDING

210 Montague Ave, Greenwood, SC 29649-1935

Estimated value:
$170,000
3,083 sqft 0.80 AC lot
View details
212 Grace St
OFFICE BUILDING

212 Grace St, Greenwood, SC 29649-2412

Estimated value:
$160,000
2,793 sqft
View details
425 Emerald N Rd
OFFICE BUILDING

425 Emerald N Rd, Greenwood, SC 29646-3062

Estimated value:
$320,000
5,750 sqft 0.65 AC lot
View details
514 Laurel E Ave
OFFICE BUILDING

514 Laurel E Ave, Greenwood, SC 29649-1647

Estimated value:
$65,000
1,500 sqft
View details
605 Calhoun Ave
OFFICE BUILDING

605 Calhoun Ave, Greenwood, SC 29649-1903

Estimated value:
$175,000
1,981 sqft
View details

Greenwood County, SC Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Greenwood County, SC, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 31,577 square feet of properties for sale, with an estimated market value of $4,912,900.

Sale prices for office properties in Greenwood County, SC start at $330,000, averaging $545,877, and reaching up to $1,300,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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