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Lancaster County, PA Office Spaces for Sale

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Two-Story Brick Office Building
Updated: Oct 15
Two-Story Brick Office Building

10 & 40 SYLVAN RETREAT Road, Columbia, PA 17512

$1,750,000
3.00 AC lot
Two‑story brick office building constructed in 1990
Approximately 9,187 square feet above grade
5,020‑square‑foot unfinished basement
Combined 3‑acre offering includes an adjacent property
Just off Columbia Avenue (PA Route 462), with immediate access to U.S. Route 30
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Turnkey Medical Office Facility
Updated: Aug 24
Turnkey Medical Office Facility

60 W WALNUT Street, Lancaster, PA 17603

$4,500,000
0.72 AC lot
Multiple clinical suites with dental equipment, fixtures, and furnishings in place
Flexible configuration for one multispecialty practice or multiple dental and medical users
On‑site parking at 60 W Walnut Street, Lancaster, PA 17603
0.72‑acre parcel
Central Air cooling
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Mixed-Use Building with Separate Entrances
Mixed-Use Building with Separate Entrances

112 W CHESTNUT Street, Lancaster, PA 17603

$559,900
0.02 AC lot

Brick property combines first-floor retail or office space with a two-bedroom apartment on the upper floors.

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Multi-Suite Medical Office Building
Multi-Suite Medical Office Building

2445 Marietta Ave, Lancaster, PA 17601

$1,500,000
5,000 sqft 2.80 AC lot

Two suites combine a dedicated medical layout with flexible professional office space.

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Two-Building Office Property
Two-Building Office Property

1119 MANHEIM Pike, Lancaster, PA 17601

$375,000
0.11 AC lot

I-2 Industrial zoning, Manheim Pike frontage, and 15 on-site parking spaces support flexible commercial use.

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Medical Office Building with Flexible Suites
Medical Office Building with Flexible Suites

640 E OREGON Road, Lititz, PA 17543

$2,100,000
1.50 AC lot

Medical office space offers separate suite access, on-site parking, and heavy power for imaging and other equipment.

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Office Building with Rear Egress
Office Building with Rear Egress

743 S BROAD Street, Lititz, PA 17543

$2,400,000
0.96 AC lot

Block construction with central heating, central air conditioning, and a dedicated parking lot.

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Flex Building with Drive-In Doors
Flex Building with Drive-In Doors

217 S MAIN STREET, Manheim, PA 17545

$975,000
8,555 sqft

Office and warehouse areas create a versatile commercial configuration.

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Office Building with Three Suites
Office Building with Three Suites

3904 Abel Dr, Columbia, PA 17512

$1,175,000
7,120 sqft

A two-story configuration includes private parking and connections to public utilities.

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Office or Retail Building with Rear Egress
Office or Retail Building with Rear Egress

743 S Broad St, Lititz, PA 17543

$2,400,000
9,200 sqft 0.96 AC lot

Multi-use office building on nearly an acre with rear egress to a Route 501 signal for convenient access and operations.

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Mixed-Use Property with Auto Garage
Mixed-Use Property with Auto Garage

3525 COLUMBIA AVENUE, Lancaster, PA 17603

$1,595,000
4,890 sqft

A residence sits in front of an air-conditioned garage equipped for vehicle service.

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Medical Office Building with Suite Options
Medical Office Building with Suite Options

640 E Oregon Rd, Lititz, PA 17543

$2,100,000
7,501 sqft

Medical office space offers flexible demising, dedicated entrances, substantial parking, and power suitable for imaging equipment.

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Office Building with Private Offices
Office Building with Private Offices

6 S CHURCH STREET, Quarryville, PA 17566

$800,000
4,332 sqft

Built in 1954, the property offers conference rooms and open work areas for professional office use.

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Freestanding Office Condominium
Freestanding Office Condominium

342 E Main St, Leola, PA 17540

$1,095,000
6,490 sqft

Two-level office property with private suites, shared meeting areas, and occupied second-floor offices along East Main Street.

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Renovated Office Units with Open Plans
Renovated Office Units with Open Plans

1695 STATE STREET, East Petersburg, PA 17520

$924,000
77,000 sqft

Flexible suites include private offices, conference rooms, and shared kitchen amenities.

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Furnished Office Suite
Furnished Office Suite

158 E KING STREET #300, Lancaster, PA 17602

$109,736
4,988 sqft

Configured with private offices, collaborative work areas, and dedicated conference space in a walkable downtown setting.

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Former Bank Branch Building
Former Bank Branch Building

325 Locust St, Columbia, PA 17512

$500,000
3,724 sqft 0.18 AC lot

Former bank branch building offers flexible space for office, professional services, retail, or creative use.

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Office Suite with On-Site Amenities
Office Suite with On-Site Amenities

100 W MILLPORT ROAD, Lititz, PA 17543

$223,605
14,907 sqft

Suite 1B includes an on-site café, fitness center, and locker room.

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Mixed-Use Property with Separate Entrances
Mixed-Use Property with Separate Entrances

112 W CHESTNUT STREET, Lancaster, PA 17603

$559,900
1,864 sqft

First-floor retail and office space pairs with a two-bedroom apartment above.

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Clear-Span Open Office Suite
Clear-Span Open Office Suite

313 W LIBERTY STREET #335, Lancaster, PA 17603

$156,135
10,409 sqft

Office suite with reception, mailroom, private restroom, server room, and large windows in a wheelchair-accessible office building.

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Office Suites with On-Site Parking
Office Suites with On-Site Parking

850 Greenfield Road, Lancaster, PA 17601

$350,000
64,000 sqft

Flexible layouts combine private offices, open work areas, shared meeting space, and full ADA accessibility.

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Professional Office Building
Professional Office Building

352 E Main St, Leola, PA 17540

$1,175,000
7,200 sqft

High-visibility office building offering two executive suites plus leased individual offices.

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Historic Mixed-Use Property
Historic Mixed-Use Property

204 E Main St, Mount Joy, PA 17552

$234,000
1,167 sqft

Flexible commercial and residential layout with updated kitchens and bathrooms, wood floors, and a former storefront area.

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Brick Mixed-Use Property
Brick Mixed-Use Property

405 S MARKET STREET, Elizabethtown, PA 17022

$649,900
4,664 sqft

Two commercial buildings include office and optical retail space, plus three one-bedroom apartments.

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Lancaster County, PA Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Lancaster County, PA, showcased through 67 active listings on our real estate platform. These investment opportunities span a total of 710,744 square feet of properties for sale, with an estimated market value of $40,101,755.

Sale prices for office properties in Lancaster County, PA start at $31,537, averaging $1,113,937, and reaching up to $4,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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