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Lancaster County, PA Office Properties & Spaces for Sale

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33 results
East Petersburg Commercial Opportunity
$700,000
0.59 Acres

East Petersburg Commercial Opportunity

5939 MAIN Street, East Petersburg, PA 17520

Prime commercial property with retail, warehouse, and rental income.

  • Prime commercial location with high traffic count on Route 72.
  • Approximately 5,000 sq. ft. of retail space with offices and 5,000 sq. ft. of warehouse space.
  • Warehouse features two 10'x10' overhead garage doors and 16‑foot ceilings.
  • Additional income from separately rented 600 sq. ft. commercial space (fitness center) and a one‑bedroom apartment.
  • Approximately 16 parking spaces.
Updated: Mar 10
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Historic Mixed-Use Commercial Building
$565,000
0.06 Acres

Historic Mixed-Use Commercial Building

22 S 2ND Street, Columbia, PA 17512

Unique property blending historic charm with modern convenience in downtown Columbia.

  • Prime downtown location suitable for a variety of commercial and residential uses.
  • Unique live‑work opportunity with a second‑floor living space and small, fenced‑in yard.
  • Historic building (built in 1900) featuring original architectural details, including cantilevered storefront display windows and intricate brickwork.
  • Updated features include refinished wood floors and custom hand‑blown glass light fixtures.
  • Currently operating as a successful business with existing infrastructure for retail, event space, and food service.
Updated: Jan 6
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Ephrata Office Building For Sale
$285,000
0.10 Acres

Ephrata Office Building For Sale

Move-in ready office building in the heart of downtown Ephrata.

112 W MAIN Street, Ephrata, PA 17522
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Commercial Space on Busy Route
$525,000
0.48 Acres

Commercial Space on Busy Route

Commercial space suitable for medical, retail, or storage purposes.

915 N HANOVER Street, Elizabethtown, PA 17022
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Lancaster Office Investment Opportunity
$6,000,000
2.68 Acres

Lancaster Office Investment Opportunity

Stabilized office property leased until 2030 in Lancaster, PA.

3020 COLUMBIA Avenue, Lancaster, PA 17603
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Lancaster Office Space For Sale
$151,000

Lancaster Office Space For Sale

Second-floor office space with private offices and conference room.

2938-1 COLUMBIA AVENUE, Lancaster, PA 17603
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Historic Townhouse with Mixed-Use Potential
$1,895,000
0.20 Acres

Historic Townhouse with Mixed-Use Potential

Historic Lancaster townhouse with commercial space and residential living.

121-123 E KING Street, Lancaster, PA 17602
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Medical Office Building in Lititz
$2,100,000
1.50 Acres

Medical Office Building in Lititz

7,501 SF medical office building for sale or lease.

640 E OREGON Road, Lititz, PA 17543
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Mixed-Use Redevelopment Opportunity
$4,500,000
2.30 Acres

Mixed-Use Redevelopment Opportunity

2.3-acre mixed-use property in Lancaster City with redevelopment potential.

301 E LIBERTY STREET, Lancaster, PA 17602
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Lititz Office/Retail Building For Sale
$2,400,000
0.96 Acres

Lititz Office/Retail Building For Sale

9,200 SF office building on 0.96 acres in Lititz, PA.

743 S BROAD Street, Lititz, PA 17543
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Professional Office Building For Sale
$5,000,000
39,610 SF

Professional Office Building For Sale

39,610 SF office building on 2.68 acres available.

3020 COLUMBIA AVENUE, Lancaster, PA 17603
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Leola Office Building For Sale
$1,200,000
8,832 SF

Leola Office Building For Sale

8,832 SF office building with tenant and vacant suite.

20 Trinity Dr, Leola, PA
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Redone Brick Building in Ephrata
$725,000
0.63 Acres

Redone Brick Building in Ephrata

Two-story brick building with rental income potential in high-traffic location.

875 E MAIN STREET, Ephrata, PA 17522
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Flex Building in East Petersburg
$1,495,000
1,311 SF

Flex Building in East Petersburg

Freestanding flex building with office and warehouse space for rent.

1176 Enterprise Ct, East Petersburg, PA 17520
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Lancaster Industrial Investment Opportunity
Contact for pricing
208,993 SF

Lancaster Industrial Investment Opportunity

208,993 SF industrial building with long-term tenant.

301 Richardson Dr, Lancaster, PA 17603
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Professional Condo in Downtown Lancaster
$115,000
1,242 SF

Professional Condo in Downtown Lancaster

Upscale condo with offices and conference room in downtown Lancaster.

128 East Grant Street, Lancaster, PA 17602
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Adaptive Re-Use Project Opportunity
$699,000
7,702 SF

Adaptive Re-Use Project Opportunity

Two buildings with courtyard, ideal for creative revitalization project.

20 N 2nd St, Columbia, PA
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Freestanding Building with Parking Area
$575,000
1,128 SF

Freestanding Building with Parking Area

High-traffic location, leased through 2027, future owner/user opportunity.

454 N Prince St, Lancaster, PA
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Main Street Commercial Building For Sale
Contact for pricing
3,009 SF

Main Street Commercial Building For Sale

Commercial building in Terre Hill, PA with retail and office potential.

100 W Main Street, Terre Hill, PA 17581
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Adaptable Commercial Condo for Rent
$149,900
2,200 SF

Adaptable Commercial Condo for Rent

Versatile 2,200 SF condo with CBD zoning.

222 South Market Street, Elizabethtown, PA
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Lancaster Commercial Property with Income
$339,000
2,925 SF

Lancaster Commercial Property with Income

Commercial property near Lancaster City with residential income potential.

911 East King Street, Lancaster, PA 17602
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Downtown Lancaster Investment Opportunity
$2,295,000
30,008 SF

Downtown Lancaster Investment Opportunity

Three-parcel assemblage in downtown Lancaster with NNN lease.

37-45 N. DUKE STREET, Lancaster, PA 17602
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Ephrata Mixed-Use Commercial Building
$990,000
0.89 Acres

Ephrata Mixed-Use Commercial Building

Value-add opportunity in a high-visibility location near major landmarks.

560 S READING ROAD, Ephrata, PA 17522
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New Holland Net Lease Investment
$3,650,000
21,048 SF

New Holland Net Lease Investment

Net leased investment opportunity with established tenant, TruckPro.

220 Orlan Rd, New Holland, PA 17557
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Lancaster County, PA Office Properties & Spaces Investment Opportunities Market Analysis

Explore 33 office properties & spaces for sale in Lancaster County, PA, showcased through 33 active listings on our real estate platform. These investment opportunities span a total of 145,343,163 square feet of properties for sale, with an estimated market value of $1,257,380,000.

Sale prices for office spaces in Lancaster County, PA start at $80,000, averaging $850,730, and reaching up to $13,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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