Lancaster County, PA Commercial Real Estate for Sale

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289 properties
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Two-Unit Mixed-Use Building
Updated: Aug 4
Two-Unit Mixed-Use Building

15 N LIME Street, Lancaster, PA 17602

$595,000
2,641 sqft 0.06 AC lot
2,641‑square‑foot mixed‑use property on a 0.06‑acre lot
Ground‑floor commercial space includes two half bathrooms
Upstairs apartment has two bedrooms and two full bathrooms
Driveway parking accommodates up to four vehicles
Built in 1870 with masonry and brick construction
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Five-Unit Mixed-Use Building
Updated: Aug 18
Five-Unit Mixed-Use Building

205 E KING Street, Lancaster, PA 17602

$995,000
3,049 sqft 0.07 AC lot
Five‑unit configuration with four residential units and one ground‑floor commercial space
3,049 square feet on a 0.07‑acre lot
Brick construction dating to 1870
Carriage house includes an attached garage, lofted sleeping area, kitchen, bathroom, and private deck
Heating by forced air and hot water; ductless cooling
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Two-Story Brick Office Building
Two-Story Brick Office Building

10 & 40 SYLVAN RETREAT Road, Columbia, PA 17512

$1,750,000
3.00 AC lot

The offering combines a professional office, adjacent land, and unfinished basement space.

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Multi-Suite Medical Office Building
Multi-Suite Medical Office Building

2445 Marietta Ave, Lancaster, PA 17601

$1,500,000
5,000 sqft 2.80 AC lot

Two suites combine a dedicated medical layout with flexible professional office space.

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Mixed-Use Property with Laundromat
Mixed-Use Property with Laundromat

352 E NEW Street, Lancaster, PA 17602

$675,000
4,392 sqft 0.07 AC lot

Brick corner property combines apartments with operating laundry and restaurant components in a compact urban setting.

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Two-Unit Mixed-Use Property
Two-Unit Mixed-Use Property

347 N RESERVOIR Street, Lancaster, PA 17602

$309,900
1,518 sqft 0.05 AC lot

A vacant street-level commercial suite is paired with a leased apartment featuring its own entrance.

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Turnkey Medical Office Facility
Turnkey Medical Office Facility

60 W WALNUT Street, Lancaster, PA 17603

$4,500,000
0.72 AC lot

Multiple equipped clinical suites, furnishings, equipment, and on-site parking support a flexible healthcare layout.

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Mixed-Use Property with Auto Garage
Mixed-Use Property with Auto Garage

451 S PRINCE STREET, Lancaster, PA 17603

$595,000
5,821 sqft

An automotive repair garage and recently renovated apartment are arranged on separate levels.

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Freestanding Flex Space with Showroom
Freestanding Flex Space with Showroom

858 MANOR Street, Lancaster, PA 17603

$549,000
0.19 AC lot

Brick construction combines a customer-facing showroom with warehouse and storage areas.

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Grocery and Cold Storage Facility
Grocery and Cold Storage Facility

3093 & 3097 OLD PHILADELPHIA Pike, Bird In Hand, PA 17505

$3,690,000
2.50 AC lot

Multiple buildings accommodate food retail, cider production, refrigerated storage, offices, and maintenance functions.

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Flex Building with Drive-In Doors
Flex Building with Drive-In Doors

217 S MAIN STREET, Manheim, PA 17545

$975,000
8,555 sqft

Office and warehouse areas create a versatile commercial configuration.

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Mixed-Use Building with Separate Entrances
Mixed-Use Building with Separate Entrances

112 W CHESTNUT Street, Lancaster, PA 17603

$559,900
0.02 AC lot

Brick property combines first-floor retail or office space with a two-bedroom apartment on the upper floors.

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Commercial Land with Storefront Zoning
Commercial Land with Storefront Zoning

601 E MAIN Street, Lititz, PA 17543

$715,000
1.61 AC lot

Corner parcel with Neighborhood Storefront District zoning and public water and sewer availability.

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Office Building with Three Suites
Office Building with Three Suites

3904 Abel Dr, Columbia, PA 17512

$1,175,000
7,120 sqft

A two-story configuration includes private parking and connections to public utilities.

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NNN Retail Building with Pizza Tenant
NNN Retail Building with Pizza Tenant

250 S CHERRY Alley, Elizabethtown, PA 17022

$395,000
0.16 AC lot

A separate area may accommodate partial owner occupancy or an additional tenant alongside the existing leased space.

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Renovated Restaurant Property
Renovated Restaurant Property

30 W LEMON Street, Lancaster, PA 17603

$1,500,000
0.07 AC lot

CB1-zoned restaurant property with modern windows and a refreshed interior.

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Office or Retail Building with Rear Egress
Office or Retail Building with Rear Egress

743 S Broad St, Lititz, PA 17543

$2,400,000
9,200 sqft 0.96 AC lot

Multi-use office building on nearly an acre with rear egress to a Route 501 signal for convenient access and operations.

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Mixed-Use Building With Storefront
Mixed-Use Building With Storefront

101 PEARL Street, Lancaster, PA 17603

$449,900
2,178 sqft 0.05 AC lot

Brick property combining a street-level convenience storefront with a three-bedroom apartment and separate utilities.

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Turnkey Restaurant and Bar
Turnkey Restaurant and Bar

551 W King St, Lancaster, PA 17603

$1,900,000
11,000 sqft

Recently renovated restaurant and bar with a strong beer-on-tap program and live entertainment, plus an included apartment.

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Two-Building Office Property
Two-Building Office Property

1119 MANHEIM Pike, Lancaster, PA 17601

$375,000
0.11 AC lot

I-2 Industrial zoning, Manheim Pike frontage, and 15 on-site parking spaces support flexible commercial use.

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Mixed-Use Property with Auto Garage
Mixed-Use Property with Auto Garage

3525 COLUMBIA AVENUE, Lancaster, PA 17603

$1,595,000
4,890 sqft

A residence sits in front of an air-conditioned garage equipped for vehicle service.

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Entitled Commercial Land for Assisted Living
Entitled Commercial Land for Assisted Living

306 S DUKE STREET, Millersville, PA 17511

$6,375,000
3.00 AC lot

Recorded approvals and planned site improvements support development of a personal care facility.

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Medical Office Building with Suite Options
Medical Office Building with Suite Options

640 E Oregon Rd, Lititz, PA 17543

$2,100,000
7,501 sqft

Medical office space offers flexible demising, dedicated entrances, substantial parking, and power suitable for imaging equipment.

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C-2 Commercial Land
C-2 Commercial Land

3908 ABEL Drive, Columbia, PA 17512

$294,900
0.80 AC lot

Development site with engineered plans for a flex and office building, plus public water and sewer availability.

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Lancaster County, PA Commercial Real Estate Market Trends and Statistics

Explore 289 commercial real estate for sale in Lancaster County, PA, showcased through 289 active listings on our real estate platform. These investment opportunities span a total of 3,089,584 square feet of properties for sale, with an estimated market value of $207,557,551.

Sale prices for business properties in Lancaster County, PA start at $31,482, averaging $1,115,900, and reaching up to $11,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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