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    Lancaster County, PA Medical Office Space for Lease

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    14 properties
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    Endcap Retail Shell
    Updated: Jun 17
    Endcap Retail Shell

    84 DOE RUN Road, Manheim, PA 17545

    $29,546/Mo
    Under construction end cap retail/office space at 84 Doe Run Rd in Manheim’s retail district
    Never occupied 2,118 SF vanilla shell with frame construction
    Located on Doe Run Rd with exposure to 12,000+ vehicles per day
    Join an established tenant mix including UPMC Primary Care and CPRS Physical therapy
    Central Air and Forced Air heating included
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    Medical Office Suites with Separate Entrances
    Updated: Mar 26, 2025
    Medical Office Suites with Separate Entrances

    640 E OREGON Road, Lititz, PA 17543

    $180,024/Mo
    7,501 sf medical office space for lease.
    Divisible into three suites with separate entrances (3,120 sf, 2,800 sf, and 1,581 sf).
    Easy access to Routes 501, 272, and 222; 10 minutes from Route 30 via 222.
    Approx. 45 parking spaces on site.
    Heavy power available for imaging and other medical equipment.
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    Medical and Professional Office Suite
    Medical and Professional Office Suite

    357 W Main St, Leola, PA 17540

    $15.95 SF/Yr
    2,626 sqft

    Flexible suite suitable for medical and professional services in an active, established tenant environment.

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    Medical Office Suite
    Medical Office Suite

    351 W Main St, Leola, PA 17540

    $10.95 SF/Yr
    918 sqft

    A versatile professional suite designed for medical, financial, and service-based operations in Leola.

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    Millersville Retail/Office Space Available
    Millersville Retail/Office Space Available

    515B Leaman Ave, Millersville, PA 17551

    $11.75 SF/Yr
    2,400 sqft

    Former bank space near Millersville University.

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    Lancaster Medical Office Space Available
    Lancaster Medical Office Space Available

    802 New Holland Ave, Lancaster, PA

    $16 SF/Yr
    10,694 sqft

    Medical office space in accessible building, convenient Lancaster location.

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    East Petersburg Retail/Office Space
    East Petersburg Retail/Office Space

    5345 Main St, East Petersburg, PA

    Contact for pricing
    1,290 sqft

    Retail or office space with high visibility and traffic.

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    Class A Medical Office Building
    Class A Medical Office Building

    205-160 N Pointe Blvd, Lancaster, PA 17601

    $35,255 SF/Yr

    Recently remodeled common areas in a Class A office building offer a polished setting for medical and professional tenants.

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    First-Floor Office/Medical Space Available
    First-Floor Office/Medical Space Available

    2310 Harrisburg Pike, Lancaster, PA 17601

    Contact for pricing
    2,000 sqft

    2,000 SF office/medical space near Penn Medicine Lancaster General.

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    Lancaster Commercial Space For Rent
    Lancaster Commercial Space For Rent

    600 Eden Road, Lancaster, PA 17601

    $17.50 SF/Yr

    Commercial space available for rent in Lancaster, Pennsylvania.

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    Medical Office Near Park City
    Medical Office Near Park City

    810 Plaza Boulevard, Lancaster, PA

    Contact for pricing
    4,945 sqft

    Medical office space for lease near Park City Mall.

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    Lancaster Office/Medical Building for Rent
    Lancaster Office/Medical Building for Rent

    3050 Hempland Rd, Lancaster, PA

    $23.50 SF/Yr
    53,207 sqft

    53,207 SF office/medical building with flexible zoning and ample parking.

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    Class A Office/Medical Building
    Class A Office/Medical Building

    40 ROSEVILLE E ROAD, Lancaster, PA 17601

    $127,536 SF/Yr

    To be built office/medical building.

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    Professional/Medical Office Space For Lease
    Professional/Medical Office Space For Lease

    40 E Roseville Rd, Lancaster, PA 17601

    $24 SF/Yr

    Professional or medical office space available for single tenant.

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    Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 14 Active listings in Lancaster County, PA, we suggest exploring alternatives. Similar 3 Properties for Sales.

    Similar Spaces for Sale in Lancaster County, PA

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Medical Office Building with Imaging Power
    Medical Office Building with Imaging Power

    640 E OREGON Road, Lititz, PA 17543

    $2,100,000
    1.50 AC lot

    Medical suites with separate entrances and heavy power for imaging equipment in a parking-rich setting.

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    Medical Office Building For Sale
    Medical Office Building For Sale

    640 E OREGON ROAD, Lititz, PA 17543

    $2,100,000
    7,501 sqft

    Medical office building with suites available for sale or lease.

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    Medical Building Near Residential Community
    Medical Building Near Residential Community

    3045 Marietta Ave, Lancaster, PA

    $1,950,000
    15,710 sqft 1.69 AC lot

    Three-story medical building with grade-level entrances and elevator access.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land Parcel with Utilities
    Commercial Land Parcel with Utilities

    2585 Maple Lane, Pittsburgh, PA 15241

    $50,000/Mo

    Level, fully serviced commercial parcel with approvals in place and signage permitted up to 20 sq ft.

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    Prime Pad Site for Lease
    Prime Pad Site for Lease

    9 Old State Rd, Belmont, NH 03220

    Contact for pricing

    Highly visible 1.74 acre pad site in Belmont, NH.

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    Prime Lexington Outlot Opportunity
    Prime Lexington Outlot Opportunity

    3330 Partner Place, Lexington, KY 40503

    Contact for pricing

    Outlot for ground lease or build-to-suit in South Lexington.

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    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    View details

    Lancaster County, PA Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Lancaster County, PA with 14 listings featured on our commercial real estate exchange. The current inventory includes 69,845 square feet of properties with an estimated lease value of $78.15 SF/Yr.

    Estimated lease rates for Medical Office Space in Lancaster County, PA begin at $10.95 SF/Yr, with an average of $15.63 SF/Yr and extend to $23.50 SF/Yr.
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    Featured Lancaster County Real Estate Agencies

    Realmo connects you with licensed Lancaster County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Mountain Realty ERA Powered
    2938 Columbia Avenue, Suite 602 Lancaster, PA 17603
    Phone: 17175727423
    www.eramountainrealty.com
    Puffer Morris Real Estate Inc.
    222 W. Orange Street Lancaster, PA 17603
    Phone: 17175383412
    puffermorris.com
    RE/MAX Associates of Lancaster
    500 Delp Road Lancaster, PA 17601
    Phone: 17175692222
    www.LancasterRMX.com

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