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San Ysidro, CA Office Properties & Spaces for Sale

74 results
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Mixed-Use Property Near U.S.-Mexico Border
$4,099,000
0.31 Acres

Mixed-Use Property Near U.S.-Mexico Border

165 W San Ysidro Blvd, San Ysidro, CA 92173

New mixed-use property in San Ysidro, near U.S.-Mexico border.

  • Prime location: Just 1.5 miles from the world's busiest U.S.-Mexico border crossing.
  • New construction (2021) featuring 7 units and 7,989 SF of rentable space.
  • Flexible CC‑3‑4 zoning allows for diverse business uses.
  • Mixed‑use property ideal for owner‑users or investors.
  • Equipped with grease interceptors and elevator service.
Updated: Apr 3
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Industrial Condo Near Otay Border
$815,000
1,524 SF

Industrial Condo Near Otay Border

10050 Via De La Amistad, San Diego, CA 92154

Industrial condominium near Otay Border truck crossing with warehouse space.

  • Prime Location: Directly across from the Otay Border Truck Crossing, ideal for businesses involved in international trade.
  • Versatile Space: Combines warehouse space with a roll‑up door, forklift accessibility, office/lobby, and kitchen on the first floor.
  • Flexible Office Layout: Second floor features an open concept suitable for large offices or conference space, easily convertible to individual offices.
  • Functional Amenities: Includes two bathrooms (one on each floor) and central air conditioning.
  • Industrial Condominium: Rare opportunity to own an industrial condominium unit.
Updated: Dec 12, 2025
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San Diego Commercial/Industrial Flex Space
$2,356,000
7,192 SF

San Diego Commercial/Industrial Flex Space

Multi-use commercial/industrial flex space in a sought-after San Diego location.

3065 Beyer Boulevard, San Diego, CA 92154
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Furnished Offices Near Pacific Beach
Contact for pricing
0.17 Acres

Furnished Offices Near Pacific Beach

Furnished offices with amenities, near the ocean in Pacific Beach.

4526-38 CASS STREET, San Diego, CA 92109
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San Diego Warehouse/Office Condo
$750,000
1,277 SF

San Diego Warehouse/Office Condo

1277 SF warehouse/office condo near Mexico border, easy freeway access.

10005 Marconi Drive, San Diego, CA 92154
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Bankers Hill Mixed-Use Opportunity
$2,849,000
3,800 SF

Bankers Hill Mixed-Use Opportunity

Three-story mixed-use building in Bankers Hill with flexible zoning.

2368 2nd AVE, San Diego, CA 92101
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Remodeled Mixed-Use Property in Hillcrest
$1,189,000
1,778 SF

Remodeled Mixed-Use Property in Hillcrest

Upgraded office and retail space in a vibrant San Diego neighborhood.

825-829 Washington St., San Diego, CA 92103
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Versatile Mixed-Use Commercial Property
$1,149,000
1,610 SF

Versatile Mixed-Use Commercial Property

Mixed-use property with office spaces, kitchens, and flex space.

2487 Kettner Blvd, San Diego, CA 92101
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Remodeled Office Condo in San Diego
$483,000
34,000 SF

Remodeled Office Condo in San Diego

Turnkey office condo in Little Italy/Downtown San Diego with parking.

2535 Kettner Blv., San Diego, CA 92101
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Downtown San Diego Mixed-Use Building
$7,900,000
29,096 SF

Downtown San Diego Mixed-Use Building

Mixed-use building in downtown San Diego with redevelopment potential.

640 Broadway, San Diego, CA 92101
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Downtown San Diego Corner Unit
$1,149,900

Downtown San Diego Corner Unit

Versatile corner unit in vibrant East Village, San Diego.

875 G St, San Diego, CA 92101
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Ocean Beach Veterinary Clinic Opportunity
$2,325,000

Ocean Beach Veterinary Clinic Opportunity

Established veterinary clinic with live-work apartment near beach.

1964 Sunset Cliffs Boulevard, San Diego, CA 92107
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Modern Retail Space in Metro North
$1,223,000
1,223 SF

Modern Retail Space in Metro North

New construction retail condo in a dynamic San Diego location.

4473 30th St, San Diego, CA 92116
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San Diego East Village Office
$3,900,000

San Diego East Village Office

Office space in the heart of San Diego’s East Village.

1045 14th Street, San Diego, CA 92101
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Miramar Office Opportunity For Sale
$965,425

Miramar Office Opportunity For Sale

1,679 SF office space in a central, garden-style setting.

9888 Carroll Centre Road |, San Diego, CA 92126
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San Diego Office Building For Sale
$2,800,000
4,775 SF

San Diego Office Building For Sale

4,775 SF office building on a 0.94-acre lot.

3704 Ruffin Rd, San Diego, CA 92123
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Medical Office Building For Sale
Contact for pricing
22,689 SF

Medical Office Building For Sale

22,689 SF medical office building with long-term corporate lease.

7150 El Cajon Boulevard, San Diego, CA 92115
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Bankers Hill Mixed-Use Opportunity
$2,849,000
3,800 SF

Bankers Hill Mixed-Use Opportunity

Three-story mixed-use building in Bankers Hill with flexible zoning.

2368 2nd Ave, San Diego, CA 92101
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Bankers Hill Mixed-Use Property
$3,800,000
6,844 SF

Bankers Hill Mixed-Use Property

Centrally located property in Bankers Hill with office and retail.

3356-3368 2nd Avenue, San Diego, CA 92103
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Turnkey Medical Office in San Diego
$2,400,000
3,076 SF

Turnkey Medical Office in San Diego

Freestanding medical office building in desirable healthcare corridor.

3399 1st Ave, San Diego, CA 92103
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Furnished Office Space Available
$4,150,000
3,600 SF

Furnished Office Space Available

Sublease office space with flexible options and furnishings available.

1045 14th St, San Diego, CA
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3,334 SF Office /Medical For Sale
Contact for pricing
3,334 SF

3,334 SF Office /Medical For Sale

3,334 SF Office /Medical For Sale

3630 Enterprise Street, San Diego, CA 92110
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Two-Tenant Office Building Near Beach
$2,500,000
0.13 Acres

Two-Tenant Office Building Near Beach

Fully occupied office building with multi-family development potential.

1300 Grand Ave, San Diego, CA
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San Diego Warehouse Condo
$750,000
1,277 SF

San Diego Warehouse Condo

Industrial warehouse condo for sale near Mexico border.

10005 Marconi Drive, San Diego, CA 92154
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San Ysidro, CA Office Properties & Spaces Investment Opportunities Market Analysis

Explore 74 office properties & spaces for sale in San Ysidro, CA, showcased through 74 active listings on our real estate platform. These investment opportunities span a total of 13,652 square feet of properties for sale, with an estimated market value of $4,099,000.

Sale prices for office spaces in San Ysidro, CA start at $4,099,000, averaging $4,099,000, and reaching up to $4,099,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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