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Spartanburg County, SC Office Properties & Spaces for Lease

68 results
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Highway 290 Retail Development Space
$40 SF/Yr
9,850 SF

Highway 290 Retail Development Space

1723 East Main St, Duncan, SC 29334

Retail/office space in growing Duncan market near Highway 290.

  • High traffic location on HWY 290 (\u00b137,500 VPD).
  • Located in a rapidly growing commercial and industrial market.
  • One of the last parcels available for new retail development in the area.
  • Surrounded by high‑paying distribution & manufacturing jobs, residential growth, I‑85, and a Greenville Tech College campus.
  • Join established tenants like McAlisters Deli, Tropical Smoothie Cafe, and AT&T.
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Spartanburg CBD Office Space
$1,000 / Mo
760 SF

Spartanburg CBD Office Space

389 E Henry St, Spartanburg, SC 29302

Multi-tenant office building in Spartanburg's central business district.

  • Located in Spartanburg's CBD
  • Multi‑tenant professional office building
  • On‑site parking available
  • Zoned LOD (Limited Office District)
  • Year Built: 1978
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Office Space Near I-85
$3 SF/Yr
4,800 SF

Office Space Near I-85

Flexible office space near I-85 and major transportation hubs.

1101 Syphrit Rd, Wellford, SC 29385
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Spartanburg Storefront Retail/Office Space
$15 SF/Yr
2,046 SF

Spartanburg Storefront Retail/Office Space

Renovated 2,046 SF retail/office space in downtown Spartanburg.

512 E Main St, Spartanburg, SC 29302
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Spartanburg Office Space Available
$17 SF/Yr
3,200 SF

Spartanburg Office Space Available

Office space available for lease in Spartanburg, South Carolina.

229 Magnolia St, Spartanburg, SC 29306
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Spartanburg Office Space Available
$17 SF/Yr
1,660 SF

Spartanburg Office Space Available

Office space for rent in Spartanburg, South Carolina.

210 Ezell St, Spartanburg, SC 29306
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New Retail Development Near Schools
$26 SF/Yr
22,400 SF

New Retail Development Near Schools

Retail space for lease in new Woodruff development.

1025 Cross Anchor Rd, Woodruff, SC 29388
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Historic Mill Office Space Available
$28 SF/Yr
53,571 SF

Historic Mill Office Space Available

Creative office space in a vibrant mixed-use community.

1802 Drayton Rd, Spartanburg, SC 29307
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Spartanburg Office Space For Rent
Contact for pricing
1,700 SF

Spartanburg Office Space For Rent

Office space available for rent in Spartanburg, SC.

135 West Main Street Ext, Spartanburg, SC 29307
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Spartanburg Office Space For Rent
$39 SF/Yr
120 SF

Spartanburg Office Space For Rent

Office space available for lease in Spartanburg, South Carolina.

2375 E Main St, Spartanburg, SC 29307
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Office Space for Rent
Contact for pricing

Office Space for Rent

Office space available for rent in Spartanburg, SC.

Cedar Springs Rd, Spartanburg, SC 29302
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Office Space Available For Rent
Contact for pricing
1,200 SF

Office Space Available For Rent

Office space available for rent in Boiling Springs, SC.

2555 Boiling Spgs Rd, Boiling Springs, SC
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Premier Office Suite For Rent
Contact for pricing
425 SF

Premier Office Suite For Rent

Executive office suite in a premier location with ample natural light.

1451 E Main St, Spartanburg, SC 29307
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Office Space Near Baseball Stadium
Contact for pricing
176 SF

Office Space Near Baseball Stadium

Office space with street frontage, near new baseball stadium.

128 Magnolia St, Spartanburg, SC 29306
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Main Street Retail Opportunity
Contact for pricing
2,300 SF

Main Street Retail Opportunity

Retail and office space with high traffic frontage.

194 E Main St, Spartanburg, SC 29306
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Office Space Near Shopping Center
Contact for pricing
1,866 SF

Office Space Near Shopping Center

Office space for rent across from Willow Place Shopping Center.

1586 Skylyn Dr, Spartanburg, SC 29307
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Westside Office/Medical Space Available
Contact for pricing
5,461 SF

Westside Office/Medical Space Available

5461± sq ft office/medical space for rent.

225 E Blackstock Rd, Spartanburg, SC 29301
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Renovated Office Space Available
Contact for pricing
2,040 SF

Renovated Office Space Available

Shared, newly renovated office space for rent.

2710 Southport Rd, Spartanburg, SC 29302
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Mixed-Use Retail or Office Space
Contact for pricing
2,382 SF

Mixed-Use Retail or Office Space

New retail or office space in redeveloped Startex Mill.

21 N Main St, Wellford, SC 29385
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Downtown Spartanburg Office Space
Contact for pricing
1,395 SF

Downtown Spartanburg Office Space

Office space in downtown Spartanburg with professional finishes.

275 E Henry St, Spartanburg, SC 29306
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Office Space on Asheville Highway
Contact for pricing
1,191 SF

Office Space on Asheville Highway

Office space for lease with road frontage and ample parking.

8891 Asheville Hwy, Boiling Springs, SC 29316
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Renovated Office Space Available
Contact for pricing
1,500 SF

Renovated Office Space Available

Newly renovated office space in a high-visibility location.

901 S Pine St, Spartanburg, SC 29303
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Spartanburg Office Space for Lease
Contact for pricing
1,200 SF

Spartanburg Office Space for Lease

Office space available near downtown Spartanburg with on-site parking.

301 N Pine St, Spartanburg, SC 29302
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Office Space For Lease
Contact for pricing
2,400 SF

Office Space For Lease

Office space available for lease near Boiling Springs and Lake Bowen.

7770 Highway 9, Inman, SC 29349
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Spartanburg County, SC Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Spartanburg County, SC with 107 listings featured on our commercial real estate exchange. The current inventory includes 13,023,568,800 square feet of properties with an estimated lease value of $400 /Mo.

Estimated lease rates for Office Properties & Spaces in Spartanburg County, SC begin at $3 SF/Yr, with an average of $22 SF/Yr and extend to $90 SF/Yr.
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