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    Lexington County, SC Office Properties & Spaces for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    281 results
    SC, Columbia - 1501 Main St
    Contact for pricing

    SC, Columbia - 1501 Main St

    Discover many ways to work your way in SC, Columbia - 1501 Main St

    1501 Main St, Unit 501, Columbia, SC 29201
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    Main Street
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    Main Street

    Discover many ways to work your way in Main Street

    1320 Main St, Unit 300, Columbia, SC 29201
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    Reimagined Class-A Office Space
    $25 SF/Yr
    7,521 SF

    Reimagined Class-A Office Space

    1710 Gervais St., Columbia, SC 29201

    Newly renovated office space in prime downtown location.

    • Prime Gervais Street location, walk to Capitol, Main Street, restaurants, coffee shops, and downtown amenities.
    • Newly reimagined Class‑A office space blending iconic 1969 architecture with modern finishes.
    • Complete interior gut and rebuild underway, creating a sleek, modern, and highly functional workspace with high‑end finishes.
    • Thoughtfully designed for modern office use with open collaboration areas, private offices, conference rooms, and flexible layouts for hybrid work.
    • ±7,521 SF available on the first floor (entire floor) & ±4,000 SF available on the 2nd floor.
    Updated: Mar 6
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    Two-Story Office Building For Rent
    $16 SF/Yr
    3,960 SF

    Two-Story Office Building For Rent

    123 Lawand Dr, Columbia, SC 29210

    Two-story office building with flexible layout in central Columbia.

    • Excellent central Columbia location with easy access to I‑20/I‑26 interchange.
    • Highly functional and flexible layout suitable for various business uses (office, medical, professional services).
    • Potential to function as up to three separate office suites, accommodating single or multiple tenants.
    • ±3,960 SF two‑story masonry office building.
    • Move‑in‑ready condition.
    Updated: Mar 20
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    Office Space in Vista District
    $23 SF/Yr
    6,782 SF

    Office Space in Vista District

    Office spaces for lease in Columbia's popular Vista district.

    500 Taylor Street, Columbia, SC 29201
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    West Columbia Office/Medical Suite
    $18 SF/Yr
    12,000 SF

    West Columbia Office/Medical Suite

    Office/medical suite for lease near Lexington Medical Hospital.

    3618 Sunset Blvd., West Columbia, SC 29169
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    Office Space For Rent
    $20 SF/Yr
    15,000 SF

    Office Space For Rent

    Office suites available in Columbia, between Downtown and Forest Acres.

    3321 Forest Drive, Columbia, SC 29204
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    SC, Columbia - Stoneridge Drive
    Contact for pricing

    SC, Columbia - Stoneridge Drive

    Workspaces, services and support to help you work better in SC, Columbia - Stoneridge Drive

    140 Columbia Ave, Columbia, SC 29210
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    New Lexington County Office Space
    $23 SF/Yr
    6,500 SF

    New Lexington County Office Space

    Office space for lease in a growing Lexington County location.

    120 Brookside Parkway, Lexington, SC 29072
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    Office Suite in West Columbia
    $15 SF/Yr
    9,890 SF

    Office Suite in West Columbia

    Office suite for lease near downtown Columbia and Lexington Medical Center.

    1523 Sunset Blvd., West Columbia, SC 29169
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    Mixed-Use Property in Cayce, SC
    $825 /Mo
    7,541 SF

    Mixed-Use Property in Cayce, SC

    Mixed-use property suitable for redevelopment, retail, or office use.

    528-532 Knox Abbott Dr, Cayce, SC 29033
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    Medical Office Space For Lease
    $20 SF/Yr
    7,659 SF

    Medical Office Space For Lease

    Medical office space in prime healthcare corridor location.

    161 Medical Circle, West Columbia, SC 29169
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    Flex Space Near Interstate I-26
    $15 SF/Yr
    2,520 SF

    Flex Space Near Interstate I-26

    Professional flex and light manufacturing space with easy interstate access.

    104 Corporate Boulevard, West Columbia, SC 29169
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    Prime Office Space on Devine
    $23 SF/Yr
    12,200 SF

    Prime Office Space on Devine

    Office space for lease in the Devine Street District.

    2422 Devine Street, Columbia, SC 29205
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    Warehouse with Secured Yard
    $12 SF/Yr
    5,000 SF

    Warehouse with Secured Yard

    5,000 SF warehouse with office and secured yard.

    125 North Shorecrest Drive, Columbia, SC 29209
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    Renovated Vista Office Space
    $21 SF/Yr
    7,280 SF

    Renovated Vista Office Space

    Office space in The Vista near State House and USC.

    720 Lady Street, Columbia, SC 29201
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    Devine Street Office Space Available
    $18 SF/Yr
    10,500 SF

    Devine Street Office Space Available

    Office space for lease on highly trafficked Devine Street.

    2442 Devine St., Columbia, SC 29205
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    Columbia Office Space For Lease
    $17 SF/Yr
    7,072 SF

    Columbia Office Space For Lease

    High-quality office space in a well-located Columbia area.

    8910 Two Notch Road, Columbia, SC 29223
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    Downtown Columbia Office Space Available
    $17 SF/Yr
    8,584 SF

    Downtown Columbia Office Space Available

    Office spaces for lease in downtown Columbia, South Carolina.

    1901 Gadsden Street, Columbia, SC 29201
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    Professional Office Space For Rent
    $18 SF/Yr
    2,500 SF

    Professional Office Space For Rent

    2,500 SF office space in Irmo/Columbia corridor.

    1492 Lake Murray Blvd, Columbia, SC
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    Class A Office Sublease Opportunity
    $15 SF/Yr
    289,129 SF

    Class A Office Sublease Opportunity

    Suburban campus setting, Class A office space for sublease.

    1200 Colonial Life Blvd., Columbia, SC 29210
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    Class A Office in Columbia
    $21 SF/Yr
    87,249 SF

    Class A Office in Columbia

    Class A office building in Carolina Research Park for lease.

    7 Technology Circle, Columbia, SC 29203
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    Downtown Columbia Office Space Available
    $21 SF/Yr
    17,594 SF

    Downtown Columbia Office Space Available

    Prime office space for rent in downtown Columbia.

    1333 Main Street, Columbia, SC 29201
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    Class A Office Space Sublease
    $19 SF/Yr
    298,926 SF

    Class A Office Space Sublease

    Move-in ready Class A office space in the heart of CBD.

    1301 Gervais Street, Columbia, SC 29201
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    Lexington County, SC Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Lexington County, SC with 281 listings featured on our commercial real estate exchange. The current inventory includes 14,065,785,360 square feet of properties with an estimated lease value of $600 /Mo.

    Estimated lease rates for Office properties & Spaces in Lexington County, SC begin at $5 SF/Yr, with an average of $17 SF/Yr and extend to $40 SF/Yr.
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    Office properties & Spaces by market

    Browse Office properties & Spaces for Lease Near Lexington, SC

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