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    Anderson County, SC Office Properties & Spaces for Lease

    10 results
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    Class A Office Space
    $3,400 / Mo

    Class A Office Space

    2315 N Main St, Anderson, SC 29621

    Professional office suite for rent in Anderson, SC.

    • Prime Main Street location ideal for high‑visibility professional business.
    • Class A office building with included maintenance, electric, and water.
    • Versatile 2,800 sq ft suite suitable for medical or professional use.
    • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
    • Includes a welcoming reception area and large parking space.
    Updated: Dec 9, 2025
    View details
    Office Space on Hwy 81
    $15 SF/Yr
    2,683 SF

    Office Space on Hwy 81

    1704 E Greenville St, Anderson, SC 29621

    Office space for lease near downtown Anderson and Anderson University.

    • Great Location on Hwy 81
    • Minutes to Downtown Anderson
    • Minutes to Anderson University
    • Ground Floor Availability
    • Second Floor Availability
    View details
    Industrial Building Near I-85
    $3 SF/Yr
    420,000 SF

    Industrial Building Near I-85

    Industrial building with heavy power, multiple docks, and ample parking.

    290 Old Anderson Rd, Pendleton, SC 29670
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    Updated Office Space For Rent
    $1,000 / Mo
    840 SF

    Updated Office Space For Rent

    Recently updated office space suitable for various professional services.

    69 Main St, Pelzer, SC 29669
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    Professional Office Space Available
    Contact for pricing
    3,000 SF

    Professional Office Space Available

    Well-maintained office park near US 178/N. Main St.

    341 E Beltline Blvd, Anderson, SC 29621
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    Office Space with Recent Upgrades
    Contact for pricing
    4,200 SF

    Office Space with Recent Upgrades

    Office space featuring new exterior paint and resurfaced parking lot.

    120 E West Pkwy, Anderson, SC 29621
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    Downtown Anderson Retail Space
    $10 SF/Yr
    5,300 SF

    Downtown Anderson Retail Space

    Iconic 5,300 sqft space, prime location.

    110 Greenville St, Anderson, SC 29621
    View details
    Oak Point Plaza Executive Suites
    $20 SF/Yr
    57,107 SF

    Oak Point Plaza Executive Suites

    Anderson, SC Office Space Available

    4120-4126 Clemson Blvd, Anderson, SC 29621
    View details
    Prime Anderson Office Space
    $25 SF/Yr
    1,212 SF

    Prime Anderson Office Space

    1,800 sq ft Office in High-Traffic Area

    1107 Fant St, Anderson, SC 29621
    View details
    Belton Office Building For Lease
    Contact for pricing
    1,345 SF

    Belton Office Building For Lease

    1,345 sq ft Office Space in Belton, SC

    250 Union High Dr, Belton, SC 29627
    View details
    Based on your search, we've compiled 41 Potential Opportunities for your consideration. Besides 10 Active listings in Anderson County, SC, we suggest exploring alternatives. Similar 31 Properties for Sales.

    Explore Similar Spaces for Sale in Anderson County, SC

    Consider Similar Space for Sale. We found 31 Spaces in Nearby Locations matching your search parameters.

    Versatile Commercial Space, Anderson SC
    $685,000
    7,200 SF

    Versatile Commercial Space, Anderson SC

    Expansive commercial property with high visibility and traffic.

    405 Pearman Dairy Rd, Anderson, SC 29625
    View details
    Belton Office Building For Sale
    $315,000
    0.45 Acres

    Belton Office Building For Sale

    Versatile commercial office building with ample parking in Belton, SC.

    713 Anderson St, Belton, SC 29627
    View details
    Office Cottage Near Downtown Anderson
    $227,500
    1,400 SF

    Office Cottage Near Downtown Anderson

    Charming 1,400 sq ft office space near downtown.

    609 Bonham Ct, Anderson, SC 29621
    View details
    Move-In Ready Office Suite
    $190,000

    Move-In Ready Office Suite

    Professional office suite near hospital with high traffic and signage.

    400 N Fant St, Anderson, SC 29621
    View details
    Belton Commercial Building on Two Acres
    $595,000
    5,000 SF

    Belton Commercial Building on Two Acres

    5,000 SF commercial building with office and warehouse space.

    3361 Highway 29 N, Belton, SC 29697
    View details
    Belton Commercial Property For Sale
    $199,900
    0.29 Acres

    Belton Commercial Property For Sale

    Prime commercial property in downtown Belton, South Carolina.

    121 N Main St, Belton, SC 29627
    View details
    Versatile Mixed-Use Commercial Property
    $750,000
    0.48 Acres

    Versatile Mixed-Use Commercial Property

    Over 5,000 sq ft commercial property with residential area.

    4327 Old Mill Rd, Anderson, SC 29623
    View details
    Office Space in Anderson, SC
    Contact for pricing
    1.00 Acre

    Office Space in Anderson, SC

    Office property for sale in Anderson, South Carolina.

    2315 N Main St, Anderson, SC 29621
    View details
    Commercial Lot in Mall Park
    $35,000
    0.15 Acres

    Commercial Lot in Mall Park

    Centrally located commercial lot in Anderson, near shopping and dining.

    29 Civic Center Boulevard Ext, Anderson, SC 29625
    View details
    Office Space with Garage Bays
    $429,900

    Office Space with Garage Bays

    Two-room office with three-bay garage near Highway 76.

    103 Welpine Rd, Pendleton, SC 29670
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    Commercial Lot in Mall Park
    $34,000
    0.15 Acres

    Commercial Lot in Mall Park

    Centrally located commercial lot near shopping, dining, and civic center.

    29 Civic Ctr Blvd Unit Ext, Anderson, SC 29625
    View details
    Williamston Commercial Building For Sale
    $279,900
    1,860 SF

    Williamston Commercial Building For Sale

    Commercial building in Williamston, SC with investment and rental potential.

    203 N Hamilton St, Williamston, SC 29697
    View details
    Anderson Automotive Garage with Living Space
    $485,000
    4,290 SF

    Anderson Automotive Garage with Living Space

    Automotive garage with living space in thriving Anderson, South Carolina.

    609 Fair St, Anderson, SC 29625
    View details
    Buildable Medical Office Pad Site
    $90,000
    0.48 Acres

    Buildable Medical Office Pad Site

    Condo-style pad site in established medical park setting.

    110 Buford Ave, Anderson, SC 29621
    View details

    Anderson County, SC Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Anderson County, SC with 41 listings featured on our commercial real estate exchange. The current inventory includes 21,219,905,520 square feet of properties with an estimated lease value of $88 SF/Yr.

    Estimated lease rates for Office Properties & Spaces in Anderson County, SC begin at $3 SF/Yr, with an average of $14 SF/Yr and extend to $25 SF/Yr.
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    Browse Office Properties & Spaces for Lease Near Anderson, SC

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