Onondaga County, NY Office Properties & Spaces for Lease

$10,000 / Mo

39,245 SF

Downtown Syracuse Office Space Available

344 W Genesee St, Syracuse, NY 13202

Prime downtown Syracuse office space with parking available for lease.

• Prime downtown Syracuse office space.
• 50‑car parking included.
• Multiple suites available, some turnkey ready.
• Suites can be combined for larger space to meet your needs.
• Large windows with city views.

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Updated: Oct 29, 2025

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$500 / Mo

1,500 SF

Versatile Commercial Space in Syracuse

1807 W Genesee St, Syracuse, NY 13204

Bright commercial space ideal for offices, studio, or retail.

• High‑traffic, easily accessible location with excellent visibility.
• Flexible leasing options: entire space ($1,650/month) or individual offices ($500/month).
• Four private offices/spaces suitable for various business types.
• Beautiful hardwood floors throughout the space.
• Convenient access to major routes, restaurants, and shopping.

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Updated: Nov 5, 2025

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$1,900 / Mo

14,506 SF

East Syracuse Commercial Space Available

Class A office space in desirable East Syracuse location.

5710 Commons Park, East Syracuse, NY 13057

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$12 SF/Yr

11,039 SF

Cicero, NY Office Space Available

Versatile Office Space, Prime Location

5620 Business Ave, Cicero, NY 13039

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$6 SF/Yr

70,696 SF

Green Hills Plaza: Lease Opportunity

Versatile spaces, prime Onondaga location.

5957-6003 Salina St, Syracuse, NY 13205

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$12 SF/Yr

15,000 SF

Thresh Professional Building: Syracuse Office Space

Syracuse Office Suites: Free Month Available!

6443 Ridings Rd, Syracuse, NY 13206

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$17 SF/Yr

40,000 SF

Syracuse Creative Office Space

Modern Office Suites, Flexible Sizes

100 Elwood Davis Rd, Syracuse, NY 13212

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$18 SF/Yr

300,000 SF

One Park Place: Premier Office Space

Class A Office Suites, 2,500-80,000 SF

300 State St, Syracuse, NY 13202

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$23 SF/Yr

89,000 SF

Brittonfield Parkway Medical Office

Class A Medical Office Suites Available

4939 Brittonfield Pkwy, East Syracuse, NY 13057

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$18 SF/Yr

305,000 SF

One Lincoln Center Office Space

Syracuse, NY: Class A Office Suites

110 Fayette St, Syracuse, NY 13202

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$15 SF/Yr

52,000 SF

Syracuse Office Space: Brooklawn Corporate Center

Class A Office Suites, Syracuse, NY

6712 Brooklawn Pkwy, Syracuse, NY 13211

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$12 SF/Yr

110,000 SF

Syracuse Executive Office Space

Prestigious Syracuse office suites, 1,409-15,000 sq ft.

224 Harrison St, Syracuse, NY 13202

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$15 SF/Yr

21,160 SF

Prime North Syracuse Office Space

Modern Office Suites, Flexible Sizes Available

7293 Buckley Rd, North Syracuse, NY 13212

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$22 SF/Yr

30,000 SF

Armory Square Office Space Available

Syracuse, NY: Prime Office & Retail Space

183 Walton St, Syracuse, NY 13202

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21,965 SF

Prime Syracuse CBD Office Space

Executive Suites, 9,349-12,616 SF Available

2363 James St, Syracuse, NY 13206

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$15 SF/Yr

1,000 SF

Downtown Syracuse Retail Space

Prime Retail/Office, 1,000 SF Available

217 Montgomery St, Syracuse, NY 13202

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$225 SF/Yr

1,600 SF

Herald Place Office Space for Lease

Updated 1,600 sq ft Office in Syracuse

221 Herald Pl, Syracuse, NY 13202

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$17 SF/Yr

6,000 SF

Sherwood Office Park Suite 140

Prime Office Space, Syracuse, NY

6704 Buckley Rd, Syracuse, NY 13212

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$20 SF/Yr

173,513 SF

State Tower Office Suites

Prestigious Class A office space, downtown Syracuse.

109 Warren St, Syracuse, NY 13202

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$12 SF/Yr

140,000 SF

University Building Office Suites

Historic Charm, Modern Amenities, CBD Location

120 Washington St, Syracuse, NY 13202

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477,610 SF

Syracuse Office Space Available

Prime Downtown Syracuse Office, Retail Space

441 Salina St, Syracuse, NY 13202

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$14 SF/Yr

15,200 SF

James Street Office Building

15,200 SF Office Space Available

716 James St, Syracuse, NY 13203

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$90,000

5,800 SF

Fayetteville Medical Office Space

Prime Medical Office, Build-to-Suit

154 Burdick St, Fayetteville, NY 13066

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$180 SF/Yr

3,000 SF

Downtown Syracuse Office Space

Prime 3,000 sq ft Office in Syracuse, NY

216 Genesee St, Syracuse, NY 13202

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