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Durham County, NC Office Spaces for Lease

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Office Building in Imperial Center
Office Building in Imperial Center

4307 Emperor Boulevard, Durham, NC 27703

$29.50 SF/Yr

Three-story office building in Imperial Center Business Park available for rent.

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Class A Office Building
Class A Office Building

4819 Emperor Blvd, Durham, NC 27703

$30.50 SF/Yr

Four-story office building in Imperial Center Business Park.

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Renovated Building in Durham's 9th
Renovated Building in Durham's 9th

706 9th St, Durham, NC 27705

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3,640 sqft

Historic building with retail, office, and creative space available.

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Based on your search, we've compiled 96 Potential Opportunities for your consideration. Besides 51 Active listings in Durham County, NC, we suggest exploring alternatives. Consider Similar 45 Spaces for Sales.

Similar Spaces for Sale in Durham County, NC

Consider Similar Space for Sale. We found 45 Spaces matching your search parameters.

Durham Commercial Land Opportunity
Durham Commercial Land Opportunity

3421 N Duke Street, Durham, NC 27704

$1,300,000
2,386 sqft 0.61 AC lot

Two adjacent properties for sale in Durham's growing corridor.

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Craftsman Live-Work Bungalow
Craftsman Live-Work Bungalow

1814 Chapel Hill Road, Durham, NC 27707

$498,000
1,922 sqft 0.30 AC lot

1930s craftsman layout with porch, parlor fireplace, and separate dining, plus office-institutional zoning for flexible use.

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Historic Office Building with Porch
Historic Office Building with Porch

830 N. Mangum St., Durham, NC 27701

$649,000
3,300 sqft 0.48 AC lot

Historic structure on a large lot with flexible zoning and ample parking, suited for an office conversion or renovation.

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Industrial Flex Property with Fenced Yard
Industrial Flex Property with Fenced Yard

1015 Ellis Road, Durham, NC 27703

$1,385,000
4,940 sqft 0.74 AC lot

Three-building industrial flex site includes multiple garage bays, a converted office, and a fully fenced yard for outdoor operations.

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Colonial Square Office/Medical Building
Colonial Square Office/Medical Building

4400 Ben Franklin Boulevard, Durham, NC 27704

$3,499,000
21,532 sqft 2.10 AC lot

Multi-functional commercial building in Durham's Independence Park.

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Leased First-Floor Office Condominium
Leased First-Floor Office Condominium

5003 Southpark Drive, Durham, NC 27713

$389,000
1,386 sqft

First-floor office condominium in Southpark Professional Center, currently leased through July 2029 with tenant option to renew.

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Renovated Historic Mixed-Use Building
Renovated Historic Mixed-Use Building

319 E Chapel Hill St, Durham, NC 27701

$5,025,000
12,000 sqft

1914 building fully modernized in 2019 with added third floor and roof deck plus plentiful nearby parking.

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Historic Neoclassical Office Building
Historic Neoclassical Office Building

102 East Main Street, Durham, NC 27701

$3,200,000
8,782 sqft

Renovated 1920 bank building with terrazzo floors, marble columns, and high-ceiling office space in downtown Durham.

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Renovated Mixed-Use Restaurant and Offices
Renovated Mixed-Use Restaurant and Offices

2022 Chapel Hill Rd., Durham, NC 27707

$1,700,000

A 2017 renovated mixed-use building with full-service restaurant space, a rooftop dining patio, and second-floor office use.

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Renovated Industrial Flex Building
Renovated Industrial Flex Building

316-318 Holland St, Durham, NC 27701

$2,250,000

A 2017-renovated early 1900s industrial building with ground-floor rolling doors and a second-floor loft.

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Mid-Century Office Building
Mid-Century Office Building

1821 Green St., Durham, NC 27705

$860,000

Mid-century office building positioned near Duke’s East Campus and Ninth Street amenities.

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Industrial Flex with Laydown Yard
Industrial Flex with Laydown Yard

1101 E Cornwallis, Durham, NC 27713

$1,500,000
6,831 sqft 1.40 AC lot

Leased industrial flex with heated warehouse, office, and concrete laydown yard on about 1.4 acres.

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Renovated Office Buildings For Sale
Renovated Office Buildings For Sale

2117 Guess Road, Durham, NC 27705

$2,375,100
5,220 sqft 0.72 AC lot

Two renovated office buildings ideal for owner-user or investment.

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Modern Office Space Available
Modern Office Space Available

101-103 W Main St, Durham, NC

$1,171,000
7,306 sqft 0.20 AC lot

7,306 SF office space, currently leased until 2026.

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Office Condominium with ADA Features
Office Condominium with ADA Features

3101 Guess Road #H, Durham, NC 27705

$159,500
1,400 sqft

Well-maintained office condo with ADA bathroom and an equipped breakroom, suited for service use.

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Live-Work Craftsman Bungalow
Live-Work Craftsman Bungalow

1814 Chapel Hill, Durham, NC 27707

$498,000
1,922 sqft

Craftsman-style home with office-ready interiors, a fireplace front parlor, and flexible outdoor parking behind a detached garage.

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Historic Mixed-Use Building
Historic Mixed-Use Building

310 E. Main St., Durham, NC 27701

$1,390,000

Historic 1920s downtown building with storefront space, recording studio, and two residential apartments with a rooftop deck.

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Renovated Private Office Building
Renovated Private Office Building

1007 Broad St, Durham, NC 27705

Contact for pricing

Renovated office building with reception, private offices, and a full-height basement for flexible storage or overflow use.

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Two-Story Office and Medical Building
Two-Story Office and Medical Building

4400 Ben Franklin Boulevard, Durham, NC 27704

$3,499,000
21,532 sqft

Flexible office and medical facility with elevator, ample storage, and a loading dock, including existing leased area.

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Class-A Office Building with Retail
Class-A Office Building with Retail

110 Corcoran Street, Durham, NC 27701

Contact for pricing
130,195 sqft

A Class-A downtown office complex with ground-floor retail and extensive on-site amenity space.

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Live-Work Property with Ground-Level ADU
Live-Work Property with Ground-Level ADU

804 Madison Street, Durham, NC 27701

$895,000
2,450 sqft

Flexible downtown live-work residence with a ground-level ADU and zoning flexibility for office or rental uses.

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