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Durham, NC Office Spaces for Lease

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Found 90 office spaces for lease in Durham, NC, averaging $36/sq ft/yr. Use lease type data to compare options faster.
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Office Units with Shared Common Area
Updated: Jun 29
Office Units with Shared Common Area

3201 Yorktown Avenue, Durham, NC 27713

$350/Mo
907 sqft 1.55 AC lot
907 square feet of office space
Private office rooms with shared common area
24‑hour access
Wi‑Fi and utilities included
Located near the Research Triangle Park, Downtown Durham, and highways
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Medical Office Space with Reception Area
Updated: Dec 4, 2024
Medical Office Space with Reception Area

2609 N Duke Street, Durham, NC 27704

$18 SF/Yr
2,312 sqft 0.01 AC lot
2,312 square feet of medical office space
Reception area, private offices, conference rooms, and exam rooms
ADA‑compliant restrooms
Dedicated parking for clients and staff
Built in 1978
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First-Floor Office Units
First-Floor Office Units

1906 Carolina 54, Durham, NC 27713

$45,045/Mo
2,145 sqft 1.02 AC lot

Eight private offices, conference space, and updated finishes support a range of professional office arrangements.

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First-Floor Office Unit
First-Floor Office Unit

3604 Shannon Road Ste 105, Durham, NC 27707

$900/Mo
2,115 sqft

Furnished professional suite with six private offices, conference room, kitchenette, and two restrooms.

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CG-Zoned Commercial Space
CG-Zoned Commercial Space

2810 Hillsborough Road, Durham, NC 27705

$18 SF/Yr
2,978 sqft 0.24 AC lot

High-visibility commercial suite on Hillsborough Road with Commercial General zoning for a broad range of uses.

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Canterbury Hall Office Units
Canterbury Hall Office Units

4815 Emperor Blvd, Durham, NC 27703

$27.50 SF/Yr
2,682 sqft

Office availability at Canterbury Hall supports a range of space requirements in Durham.

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Carlisle Place Office Units
Carlisle Place Office Units

4721 Emperor Blvd, Durham, NC 27703

$29.50 SF/Yr
3,666 sqft

Lease opportunity for office users at a named commercial property in Durham.

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Private-Office Coworking Space
Private-Office Coworking Space

3201 Yorktown Avenue Ste 117, Durham, NC 27713

$350/Mo per office
907 sqft

Flexible workspace combines enclosed offices with shared common areas and round-the-clock access.

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Oxford Place Office Units
Oxford Place Office Units

1005 Slater Rd, Durham, NC 27703

$27.50 SF/Yr
1,476 sqft

Lease opportunity for office accommodations at Oxford Place in Durham, North Carolina.

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Chelsea Place Office Units
Chelsea Place Office Units

1007 Slater Rd, Durham, NC 27703

$27.50 SF/Yr
1,494 sqft

Lease opportunities are available within a named office property in Durham.

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Office Units
Office Units

4000 Sancar Way, Durham, NC 27713

$29.50 SF/Yr
1,332 sqft

Office space is available across a broad range of suite sizes.

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Renovated Historic Building in Durham
Renovated Historic Building in Durham

733 Foster St, Durham, NC 27701

$26.95 SF/Yr
11,000 sqft

Turn-key, furnished office suites in walkable downtown location.

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Serviced Office Space for Rent at NC, Durham - Spaces Mangum Street. Contact us today to book a tour!
Serviced Office Space for Rent at NC, Durham - Spaces Mangum Street. Contact us today to book a tour!

555 Mangum St, Unit 100, Durham, NC 27701

16 available spaces from 11 to 2,612 sqft
$129-$54,775/Mo per office

Find fully flexible work and meeting space in NC, Durham - Spaces Mangum Street. Book a tour & get info

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Serviced Office Space for Rent at RTP Imperial. Contact us today to book a tour!
Serviced Office Space for Rent at RTP Imperial. Contact us today to book a tour!

4819 Emperor Blvd, Unit 400, Durham, NC 27703

16 available spaces from 11 to 1,965 sqft
$129-$13,893/Mo per office

Flexible workspace in RTP Imperial. Book a tour & get info

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Move-In Ready Office Building
Move-In Ready Office Building

313 Foster St, Durham, NC 27701

Contact for pricing
4,125 sqft

Two-story office building with six offices, conference rooms, patio, and a rear loading dock plus three parking spaces.

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Retail-Office Suite with Dedicated Parking
Retail-Office Suite with Dedicated Parking

600 Foster St, Durham, NC 27701

Contact for pricing
2,285 sqft

Short-term suite with flexible use options, finished concrete floors, high ceilings, natural light, and dedicated parking.

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Main-Level Office Space
Main-Level Office Space

500 W Morgan St, Durham, NC 27701

Contact for pricing
4,101 sqft

Access-controlled workspace combines private offices, open bullpen seating, and shared conference amenities in downtown Durham.

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Open-Plan Retail Space
Open-Plan Retail Space

5234 North Roxboro Street, Durham, NC 27712

Contact for pricing
1,600 sqft

Flexible commercial suite with dual entrances, shared support areas, and access to a sizable parking lot.

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Move-In Ready Pediatric Medical Suite
Move-In Ready Pediatric Medical Suite

3400 Croasdaile Dr, Durham, NC 27705

$25 SF/Yr

First-floor medical office suite with private restrooms and a specialized ABA-focused upfit for a move-in ready pediatric practice.

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Multi-Size Office Units
Multi-Size Office Units

4170 Sancar Way, Research Triangle Park, NC 27709

Contact for pricing
30,000 sqft

Office space is available for lease within Research Triangle Park.

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Miami North Office Units
Miami North Office Units

4506 S Miami Blvd, Durham, NC 27703

Contact for pricing
1,641 sqft

Office suites are available within a named Durham business park building.

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Park Forty Plaza Office Units
Park Forty Plaza Office Units

1000 Park Forty Plz, Durham, NC 27713

Contact for pricing
1,411 sqft

Office availability accommodates a range of suite sizes for lease.

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Office Space in Durham
Office Space in Durham

324 Blackwell Street, Durham, NC 27701

$29.95 SF/Yr
9,778 sqft

Office space available for lease in Durham, North Carolina.

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Office Suite with Executive Offices
Office Suite with Executive Offices

3710 University Dr, Durham, NC 27707

Contact for pricing
1,335 sqft

Suite 302 offers a simple layout with five executive offices and an entry and waiting area.

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Durham, NC Office Spaces Lease Rates & Market Statistics

Explore 90 Office Spaces for lease in Durham, NC on Realmo, a commercial real estate exchange covering the Durham area. The current inventory totals 1,297,955 square feet of properties — an average of ~14,400 SF per listing.

Asking lease rates for Office Spaces in Durham start at $4.63 SF/Yr, average $36.31 SF/Yr, and reach $252 SF/Yr at the top of the market. The local average of $36.31 SF/Yr is 47% above the North Carolina state average of $24.71 SF/Yr.

By space type, the market includes 63 office units, 18 office buildings and 8 coworking space listings — office buildings typically offer the lowest entry point, while office units command the highest rates.

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