Clayton, MO Office Spaces for Rent & Lease

Flexible Offices and Coworking at Pierre Laclede. Contact us today to book a tour!

7733 Forsyth Blvd, Unit 11TH, Clayton, MO 63105

16 available spaces from 11 to 2,041 sqft

$129-$19,437/Mo per office

(972) 764-8885

Flexible workspace in Pierre Laclede. Book a tour & get info

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Updated: Feb 19

Sevens Building

7777 Bonhomme Ave, Unit 1800, Clayton, MO 63105

16 available spaces from 11 to 1,999 sqft

$129-$17,029/Mo per office

Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership

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Updated: Mar 26

Downtown Clayton Office Space Available

225-235 S Meramec Ave, Clayton, MO 63105

$21.50 SF/Yr

102,600 sqft

Prime downtown Clayton location at the corner of Meramec and Shaw Ave.
Ample parking with 1,200 space parking garages adjacent to the building.
On‑site amenities including management, post office, and cafe.
High visibility from Forest Park Parkway.
Close proximity to the Courthouse.

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Renovated Office Space in Clayton

200 South Hanley Road, Clayton, MO 63105

$18 SF/Yr

30,210 sqft

Newly renovated office building with convenient access and excellent views.

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Clayton CBD Office Space

7777 Bonhomme Ave, Clayton, MO

Contact for pricing

1,464 sqft 1.16 AC lot

Move-in ready office suites in central Clayton location.

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Class A Office Tower Clayton

8182 Maryland Ave, Clayton, MO

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4,086 sqft 0.87 AC lot

Class A office tower in downtown Clayton for lease.

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Renovated Office Space in Clayton

7711 Bonhomme Avenue, Clayton, MO 63105

$26.50 SF/Yr

Multiple office suites available in Clayton with renovated common areas.

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Clayton Office Space For Rent

7733 Forsyth Blvd, Clayton, MO

Contact for pricing

39,547 sqft 5.01 AC lot

Office space available with conferencing center and fitness center.

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Clayton Office Space For Rent

190 Carondelet Plaza, Clayton, MO 63105

$42.50 SF/Yr

Office space available for lease in Clayton, Missouri.

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Clayton Office Space For Rent

135 N Meramec Ave, Clayton, MO

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7,441 sqft 1.12 AC lot

7,441 square foot office space available for lease.

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Downtown Clayton Office Space Available

7808-7810 Forsyth Blvd, Clayton, MO

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4,500 sqft 0.22 AC lot

Office space for rent in downtown Clayton near amenities.

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Professionally Managed Office Space Available

8151 Clayton Rd, Clayton, MO

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2,709 sqft 1.18 AC lot

Office space for lease with covered parking and convenient location.

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Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 12 Active listings in Clayton, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Clayton Office Space Available

Saint Louis, MO 63105

$23.50 SF/Yr

10,007 sqft

Sublease opportunity in a recently renovated building with on-site amenities.

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Class A Office Space Available

1405 South Hanley Road, Brentwood, MO 63144

$28.50 SF/Yr

30,000 sqft

Premier office space in mixed-use development with excellent amenities.

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Brentwood Office Space For Lease

8374 Eager Road, Brentwood, MO 63144

$25 SF/Yr

70,000 sqft

70,000 SF office space available in premier mixed-use development.

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Luxury Clayton Mid-Rise Office Building

7800 Forsyth Blvd, Saint Louis, MO

Contact for pricing

7,033 sqft 0.44 AC lot

Luxury office building in Clayton, close to amenities and courthouse.

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Clayton, MO Office Spaces Lease Rates & Market Statistics

Browse 12 Office Spaces for lease in Clayton, MO on Realmo, a commercial real estate marketplace serving the Clayton area. The current inventory totals 196,619 square feet of properties — an average of ~16,400 SF per listing.

Asking lease rates for Office Spaces in Clayton start at $18 SF/Yr, average $27.13 SF/Yr, and reach $42.50 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $27.13 SF/Yr is 7% above the Missouri state average of $25.45 SF/Yr.

Clayton accounts for 3% of the 383 office spaces currently available across St. Louis County, where nearby markets include Saint Louis and Chesterfield. By space type, the market includes 7 office units and 3 office buildings — office buildings typically offer the lowest entry point, while office units command the highest rates.