Clayton, MO Office Spaces for Rent & Lease

Multiple Office Solutions at Sevens Building. Contact us today to book a tour!

7777 Bonhomme Ave, Unit 1800, Clayton, MO 63105

16 available spaces from 11 to 1,999 sqft

$129-$17,029/Mo per office

(972) 764-8885

Flexible workspace in Sevens Building. Book a tour & get info

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Updated: Feb 19

Flexible Offices and Coworking at Pierre Laclede. Contact us today to book a tour!

7733 Forsyth Blvd, Unit 11TH, Clayton, MO 63105

16 available spaces from 11 to 2,041 sqft

$129-$19,437/Mo per office

Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership

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Updated: Nov 22, 2025

Renovated Office Space in Clayton

200 South Hanley Road, Clayton, MO 63105

$18 SF/Yr

30,210 sqft

Convenient Clayton location with outstanding visibility
Newly renovated building lobby, entrance, elevator cabs, and common areas (2022)
Easy access to Forest Park Parkway
Walking distance to numerous restaurants, retail, and hotels
Garage and surface parking available

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Downtown Clayton Office Building

225-235 S Meramec Ave, Clayton, MO 63105

$21.50 SF/Yr

102,600 sqft

Two interconnected office buildings in downtown Clayton with on-site amenities.

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Clayton Office Space Available

101 South Hanley Road, Clayton, MO 63105

$33.50 SF/Yr

20,019 sqft

20,019 square foot office space for lease.

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Clayton CBD Office Space

7777 Bonhomme Ave, Clayton, MO

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1,464 sqft 1.16 AC lot

Move-in ready office suites in central Clayton location.

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Class A Office Tower Clayton

8182 Maryland Ave, Clayton, MO

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4,086 sqft 0.87 AC lot

Class A office tower in downtown Clayton for lease.

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Renovated Office Space in Clayton

7711 Bonhomme Avenue, Clayton, MO 63105

$26.50 SF/Yr

Multiple office suites available in Clayton with renovated common areas.

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Clayton Office Space For Rent

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Office space available for lease in Clayton, Missouri.

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Forsyth Boulevard Commercial Space

8027 Forsyth Blvd, Clayton, MO 63105

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Commercial space available for lease on Forsyth Boulevard.

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Usable Office Space Available

7801 Clayton Rd, Clayton, MO 63117

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1,658 sqft

1,658 SF office space with excellent Clayton Road visibility.

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Downtown Clayton Office Space Available

225-235 S Meramec Ave, Clayton, MO 63105

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102,600 sqft

Two interconnected office buildings with on-site amenities and parking.

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Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 17 Active listings in Clayton, MO, we suggest exploring alternatives. Similar 1 Properties for Sales.

Similar Spaces for Sale in Clayton, MO

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Clayton Office Building For Sale

889 S Brentwood Blvd, Clayton, MO 63105

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19,330 sqft

19,330 SqFt office building in Clayton, Missouri.

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