Clayton, MO Commercial real estate for Rent & Lease

Sevens Building

7777 Bonhomme Ave, Unit 1800, Clayton, MO 63105

$129-$17,029/Mo

11-1,999 sqft

(972) 764-8885

Flexible workspace in Sevens Building. Book a tour & get info

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Updated: Feb 19

Pierre Laclede

7733 Forsyth Blvd, Unit 11TH, Clayton, MO 63105

$129-$19,437/Mo

11-2,041 sqft

Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership

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Updated: Nov 24, 2025

Downtown Clayton Office Space Available

150 N Meramec Ave, Clayton, MO

$29 SF/Yr

1,737 sqft

Downtown Clayton Location with Easy I‑170 Access
Free Visitor Parking plus Covered Tenant Garage Parking
Amenities Include Fitness Center & Express Food Market
Building Signage Opportunity
Common Area & Lobby Renovations Completed

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Clayton Office Space Available Now

231 S Bemiston Ave, Clayton, MO

$30 SF/Yr

4,288 sqft

Former law firm space with elevator exposure and tenant amenities.

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Clayton Office Space Available

130 S Bemiston Ave, Clayton, MO

$24 SF/Yr

634 sqft

Office suites available in Clayton, move-in ready, renovated common areas.

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Renovated Office Space in Clayton

200 South Hanley Road, Clayton, MO 63105

$18 SF/Yr

30,210 sqft

Newly renovated office building with convenient access and excellent views.

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Class A Office Tower Clayton

8235 Forsyth Blvd, Clayton, MO

$35 SF/Yr

2,610 sqft

Class A office tower in downtown Clayton for lease.

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Class A Office Tower Clayton

8182 Maryland Ave, Clayton, MO

$35 SF/Yr

4,086 sqft

Class A office tower in downtown Clayton for lease.

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Downtown Clayton Office Building

225-235 S Meramec Ave, Clayton, MO 63105

$21.50 SF/Yr

102,600 sqft

Two interconnected office buildings in downtown Clayton with on-site amenities.

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Clayton Office Space For Rent

30-44 N Brentwood Blvd, Clayton, MO

$14 SF/Yr

350 sqft

Office spaces in the heart of Clayton near I-170 & I-64/40.

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Clayton Office Space For Rent

7701 Forsyth Blvd, Clayton, MO

$31 SF/Yr

45,777 sqft

Office space available in Clayton, Missouri with multiple amenities.

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Clayton Office Space For Rent

7733 Forsyth Blvd, Clayton, MO

$31 SF/Yr

39,547 sqft

Office space available with conferencing center and fitness center.

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Downtown Clayton Office Space Available

165 N Meramec Ave, Clayton, MO

$29 SF/Yr

2,372 sqft

Office space for rent in downtown Clayton, Missouri.

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Clayton CBD Office Space

7777 Bonhomme Ave, Clayton, MO

$31 SF/Yr

1,464 sqft

Move-in ready office suites in central Clayton location.

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Versatile Retail Space Available

8-16 N Meramec Ave, Clayton, MO

$3,000/Mo

6,774 sqft

Adaptable space suitable for various business ventures.

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Downtown Clayton Office Space Available

168 N Meramec Ave, Clayton, MO

$29 SF/Yr

10,007 sqft

Office space in downtown Clayton with convenient access and amenities.

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Clayton Office Space Available

101 South Hanley Road, Clayton, MO 63105

$33.50 SF/Yr

20,019 sqft

20,019 square foot office space for lease.

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New Retail Space in Clayton

33 N Central Ave, Clayton, MO

Contact for pricing

2,126 sqft

New retail space in mixed-use development with high foot traffic.

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Renovated Office Space in Clayton

7711 Bonhomme Avenue, Clayton, MO 63105

$26.50 SF/Yr

Multiple office suites available in Clayton with renovated common areas.

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Clayton Office Space Available

8251 Maryland Ave, Clayton, MO

$24.50 SF/Yr

3,270 sqft

Office space available for lease in Clayton, Missouri.

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Clayton Office Space For Rent

190 Carondelet Plaza, Clayton, MO 63105

$43.50 SF/Yr

Office space available for lease in Clayton, Missouri.

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Clayton Office Space For Rent

135 N Meramec Ave, Clayton, MO

$31 SF/Yr

7,441 sqft

7,441 square foot office space available for lease.

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Clayton Office Space For Rent

222 South Central Avenue, Clayton, MO 63105

$26.50 SF/Yr

Office space available for lease in Clayton, Missouri.

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Class A Office Space Available

7700 Forsyth Blvd, Clayton, MO

$45 SF/Yr

27,666 sqft

High-end office space with many amenities and ample parking.

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Clayton Office Space For Rent

120 S Central Ave, Clayton, MO

$33 SF/Yr

4,494 sqft

Office space for rent in Clayton, Missouri.

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