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    Clayton, MO
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    Clayton, MO Commercial Real Estate for Lease

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    University City, MO Saint Louis, MO Richmond Heights, MO
    49 results
    Sevens Building
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    Pierre Laclede
    $129-$4,786/Mo

    Pierre Laclede

    7733 Forsyth Blvd, Unit 11TH, Clayton, MO 63105

    Discover many ways to work your way in Pierre Laclede

    • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
    • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
    • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
    • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
    • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
    Updated: Feb 19
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    Clayton Office Space Available Now
    $30 SF/Yr
    4,288 SF

    Clayton Office Space Available Now

    231 S Bemiston Ave, Clayton, MO

    Former law firm space with elevator exposure and tenant amenities.

    • Prime location: Very short walking distance from the Clayton Metrolink and easy access to Forest Park Parkway and Interstate 170.
    • Tenant‑exclusive amenities: Includes a bike room, fitness center, lockers, and showers.
    • On‑site conveniences: Features an on‑site café, grab‑n‑go, and tenant lounge.
    • Ample office space: Offers nine private offices, two conference rooms, a break room, and a work room.
    • Attached parking garage: Includes a five‑level garage with an automated access system.
    Updated: Nov 23, 2025
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    Class A Office Tower Clayton
    $35 SF/Yr
    2,610 SF

    Class A Office Tower Clayton

    Class A office tower in downtown Clayton for lease.

    8235 Forsyth Blvd, Clayton, MO
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    Downtown Clayton Office Building
    $21 SF/Yr
    102,600 SF

    Downtown Clayton Office Building

    Two interconnected office buildings in downtown Clayton with on-site amenities.

    225-235 S Meramec Ave, Clayton, MO 63105
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    Class A Office Tower Clayton
    $35 SF/Yr
    4,086 SF

    Class A Office Tower Clayton

    Class A office tower in downtown Clayton for lease.

    8182 Maryland Ave, Clayton, MO
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    Clayton Office Space For Rent
    $26 SF/Yr
    3,346 SF

    Clayton Office Space For Rent

    Eleven-story office building in Clayton with recent renovations.

    222 S Central Ave, Clayton, MO
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    Downtown Clayton Office Space Available
    $29 SF/Yr
    1,737 SF

    Downtown Clayton Office Space Available

    Office space for lease in downtown Clayton with amenities.

    150 N Meramec Ave, Clayton, MO
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    Clayton Office Space For Rent
    $14 SF/Yr
    350 SF

    Clayton Office Space For Rent

    Office spaces in the heart of Clayton near I-170 & I-64/40.

    30-44 N Brentwood Blvd, Clayton, MO
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    Downtown Clayton Office Space Available
    $29 SF/Yr
    2,372 SF

    Downtown Clayton Office Space Available

    Office space for rent in downtown Clayton, Missouri.

    165 N Meramec Ave, Clayton, MO
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    Professionally Managed Office Space Available
    $25 SF/Yr
    2,709 SF

    Professionally Managed Office Space Available

    Office space for lease with covered parking and convenient location.

    8151 Clayton Rd, Clayton, MO
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    Clayton CBD Office Space
    $32 SF/Yr
    1,464 SF

    Clayton CBD Office Space

    Move-in ready office suites in central Clayton location.

    7777 Bonhomme Ave, Clayton, MO
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    Upscale Office Space Available
    $30 SF/Yr
    6,125 SF

    Upscale Office Space Available

    Premium office space with amenities in Clayton, Missouri.

    8000 Maryland Ave, Clayton, MO
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    Renovated Office Space in Clayton
    $26 SF/Yr

    Renovated Office Space in Clayton

    Multiple office suites available in Clayton with renovated common areas.

    7711 Bonhomme Avenue, Clayton, MO 63105
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    Clayton Office Space Available
    $33 SF/Yr
    20,019 SF

    Clayton Office Space Available

    20,019 square foot office space for lease.

    101 South Hanley Road, Clayton, MO 63105
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    Clayton Office Space For Rent
    $31 SF/Yr
    45,777 SF

    Clayton Office Space For Rent

    Office space available in Clayton, Missouri with multiple amenities.

    7701 Forsyth Blvd, Clayton, MO
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    Clayton Office Space For Rent
    $31 SF/Yr
    39,547 SF

    Clayton Office Space For Rent

    Office space available with conferencing center and fitness center.

    7733 Forsyth Blvd, Clayton, MO
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    Versatile Retail Space Available
    $3,000/Mo
    6,774 SF

    Versatile Retail Space Available

    Adaptable space suitable for various business ventures.

    8-16 N Meramec Ave, Clayton, MO
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    Downtown Clayton Office Space Available
    $28 SF/Yr
    10,007 SF

    Downtown Clayton Office Space Available

    Office space in downtown Clayton with convenient access and amenities.

    168 N Meramec Ave, Clayton, MO
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    Clayton Office Space For Rent
    $43 SF/Yr

    Clayton Office Space For Rent

    Office space available for lease in Clayton, Missouri.

    190 Carondelet Plaza, Clayton, MO 63105
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    Clayton Office Space For Rent
    $26 SF/Yr

    Clayton Office Space For Rent

    Office space available for lease in Clayton, Missouri.

    222 South Central Avenue, Clayton, MO 63105
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    Clayton Office Space Available
    $24 SF/Yr
    3,270 SF

    Clayton Office Space Available

    Office space available for lease in Clayton, Missouri.

    8251 Maryland Ave, Clayton, MO
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    Renovated Office Space in Clayton
    $26 SF/Yr
    1,993 SF

    Renovated Office Space in Clayton

    Multiple suites available in a recently renovated building.

    7711 Bonhomme Ave, Clayton, MO
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    New Retail Space in Clayton
    Contact for pricing
    2,126 SF

    New Retail Space in Clayton

    New retail space in mixed-use development with high foot traffic.

    33 N Central Ave, Clayton, MO
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    Clayton, MO Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Clayton, MO with 49 listings featured on our commercial real estate exchange. The current inventory includes 502,114 square feet of properties with an estimated lease value of $1,262 /Mo.

    Estimated lease rates for Commercial real estate in Clayton, MO begin at $5 SF/Yr, with an average of $33 SF/Yr and extend to $140 SF/Yr.
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    Most Searched ZIP Codes in Clayton, MO

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