Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Brentwood, MO Office Properties & Spaces for Lease

    List
    Map
    Saint Louis, MO Louis, MO Kansas City, MO
    10 results
    Prime Mixed-Use Opportunity, Brentwood
    $15 SF/Yr

    Prime Mixed-Use Opportunity, Brentwood

    8503 Manchester Road, Brentwood, MO 63144

    Highly visible mixed-use property with flexible layout in desirable location.

    • High‑traffic location on Manchester Road with approximately 10,000 cars passing daily.
    • Flexible layout suitable for retail, office, or service‑based businesses.
    • Located in a desirable area with higher‑end consumers and established businesses.
    • Seller is open to leasing, creative terms, and other options.
    • Blank canvas ready for customization to suit a new owner or tenant's vision.
    Updated: Mar 19
    View details
    Brentwood Office Space For Lease
    $25 SF/Yr
    70,000 SF

    Brentwood Office Space For Lease

    8374 Eager Road, Brentwood, MO 63144

    70,000 SF office space available in premier mixed-use development.

    • +70,000 SF available on 2nd floor
    • Dedicated MetroLink stop on site for easy commuting
    • Free 5/1000 Parking in multistory parking garage
    • Located in a premier mixed‑use development
    • Open, efficient floor plan
    Updated: Nov 22, 2025
    View details
    Class A Office Space Available
    $28 SF/Yr
    12,922 SF

    Class A Office Space Available

    Premier office space in desirable St. Louis location for lease.

    8300-8324 Eager Rd, Brentwood, MO
    View details
    Manchester Road Retail/Office/Medical Space
    $16 SF/Yr
    2,600 SF

    Manchester Road Retail/Office/Medical Space

    Prime commercial space suitable for retail, office, or medical use.

    8500-8518 Manchester Rd, Brentwood, MO
    View details
    Class A Office Space Available
    $28 SF/Yr
    15,000 SF

    Class A Office Space Available

    Premier mixed-use development in desirable St. Louis market.

    1405-1413 S Hanley Rd, Brentwood, MO
    View details
    Hanley Industrial Office/Flex Space
    Contact for pricing
    6,047 SF

    Hanley Industrial Office/Flex Space

    Office/flex space in Hanley Industrial with renovation and signage.

    1201 Hanley Industrial Ct, Brentwood, MO
    View details
    Brentwood Office Space For Lease
    $25 SF/Yr
    70,000 SF

    Brentwood Office Space For Lease

    70,000 SF office space with dedicated MetroLink stop.

    8328-8374 Eager Rd, Brentwood, MO
    View details
    Creative Office Suites Available
    Contact for pricing

    Creative Office Suites Available

    Creative office suites in modernized Hanley Plaza, convenient location.

    2001 S Hanley Rd, Brentwood, MO 63144
    View details
    Brentwood Retail/Office Space Available
    Contact for pricing

    Brentwood Retail/Office Space Available

    Retail and office spaces for lease in Brentwood, Missouri.

    8800 Manchester Rd, Brentwood, MO 63141
    View details
    Brentwood Flex Space Available
    Contact for pricing
    5,515 SF

    Brentwood Flex Space Available

    5,515 SF flex space in Hanley Industrial Park.

    1300 Strassner Dr, Brentwood, MO 63144
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 10 Active listings in Brentwood, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Small Office Suite For Rent
    $21 SF/Yr
    553 SF

    Small Office Suite For Rent

    Office suite featuring two offices and a reception area.

    1750 S Brentwood Blvd, Saint Louis, MO
    View details
    Class A Office Space Available
    $28 SF/Yr
    104,000 SF

    Class A Office Space Available

    Premier St. Louis office space with unmatched amenities and access.

    Saint Louis, MO 63144
    View details
    Richmond Heights Office Space Available
    $33 SF/Yr
    3,937 SF

    Richmond Heights Office Space Available

    Office space available in a mixed-use lifestyle center.

    1-19 The Blvd, Richmond Heights, MO
    View details
    Remodeled Corporate Center For Rent
    Contact for pricing

    Remodeled Corporate Center For Rent

    Newly remodeled corporate center with covered parking and outdoor patio.

    7700-7750 Clayton Road, Richmond Heights, MO 63117
    View details

    Explore Similar Spaces for Sale in Brentwood, MO

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Brentwood Mixed-Use Opportunity on Manchester
    $550,000
    0.38 Acres

    Brentwood Mixed-Use Opportunity on Manchester

    Blank canvas with high visibility on Manchester Road.

    8503 Manchester Road, Brentwood, MO 63144
    View details
    Brentwood Office Space For Sale
    Contact for pricing
    19,569 SF

    Brentwood Office Space For Sale

    19,569 SF plug and play office space available.

    1265-1314 Strassner Dr, Brentwood, MO
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Collinsville Commercial Space For Lease
    $5,000/Mo
    5,000 SF

    Collinsville Commercial Space For Lease

    Versatile commercial space in Collinsville, available immediately.

    1902 Vandalia Street, Collinsville, IL 62234
    View details
    Cleared Lot in St Clair
    $1.00 SF/Yr

    Cleared Lot in St Clair

    1.5-acre cleared lot zoned for general commercial use.

    Saint Clair, MO 63077
    View details
    High-Traffic Commercial Land in Rolla
    $7,500/Mo

    High-Traffic Commercial Land in Rolla

    0.61 acre commercial land in high-traffic area for lease.

    704 N Bishop Avenue, Rolla, MO 65401
    View details
    Commercial Land on Kingshighway
    $5,500/Mo
    4,000 SF

    Commercial Land on Kingshighway

    Prime commercial land for lease in high-traffic Rolla location.

    1014 Kingshighway Street, Rolla, MO 65401
    View details

    Brentwood, MO Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Brentwood, MO with 10 listings featured on our commercial real estate exchange. The current inventory includes 3,884,065,175 square feet of properties with an estimated lease value of $56 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Brentwood, MO begin at $15 SF/Yr, with an average of $18 SF/Yr and extend to $25 SF/Yr.
    List
    Map

    Browse Office properties & Spaces for Lease Near Brentwood, MO

    Popular Searches in Brentwood, MO

    Most Searched ZIP Codes in Brentwood, MO

    • 63144
    • 63141

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!