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Saint Louis, MO Office Spaces for Lease

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East St Louis, IL Sauget, IL Cahokia, IL Madison, IL Washington Park, IL Granite City, IL Maplewood, MO Clayton, MO
189 properties
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Coworking and Private Offices with Flexible Terms at MO, St. Louis - Craigshire Rd. Contact us today to book a tour!
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Coworking and Private Offices with Flexible Terms at Spaces Central West End. Contact us today to book a tour!
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Office Units with Private Offices
Updated: Jun 22
Office Units with Private Offices

Saint Louis, MO 63139

$2,860/Mo
4,260 sqft 0.61 AC lot
Multiple office configurations spanning first- and second‑floor suites
First‑floor layout includes reception, full kitchen, 2 restrooms, 5 private offices, and training room
Second‑floor suite features conference room, 5 private offices, bullpen, and large storage room
Additional open‑plan suite includes 2 restrooms and 1 private room
Abundant parking plus building and pole signage
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Multi-Level Church Facility
Updated: Jul 12
Multi-Level Church Facility

Saint Louis, MO 63113

$4,000/Mo
0.33 AC lot
1905 church facility on 0.3273 acres
Lower level includes hall, kitchen, 2 large rooms, and 2 large offices available for lease
Main level has 1 large office, 1 private cubicle, and 4 additional cubicle spaces
Upper level includes 2 large offices
Sanctuary space available for lease
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Renovated Mixed-Use Commercial Building
Renovated Mixed-Use Commercial Building

Saint Louis, MO 63111

$400/Mo
0.12 AC lot

Flexible commercial property combines office suites, retail area, shared amenities, and on-site parking in a full-service lease format.

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Coworking and Private Offices with Flexible Terms at Deloitte Building. Contact us today to book a tour!
Coworking and Private Offices with Flexible Terms at Deloitte Building. Contact us today to book a tour!

100 4Th St, Unit 550, Saint Louis, MO 63102

16 available spaces from 11 to 2,019 sqft
$129-$11,723/Mo per office

Flexible workspace in Deloitte Building. Book a tour & get info

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Creative Space with Exposed Brick
Creative Space with Exposed Brick

Saint Louis, MO 63118

$1,650/Mo
0.05 AC lot

An open commercial layout with high ceilings accommodates customizable office, studio, showroom, wellness, or retail concepts.

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Renovated Office-Warehouse Flex Space
Renovated Office-Warehouse Flex Space

Saint Louis, MO 63144

$5,000/Mo
0.22 AC lot

Combined office and warehouse areas include updated employee facilities and direct loading access.

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Office Unit with Private Offices
Office Unit with Private Offices

Saint Louis, MO 63011

$1,300/Mo
0.02 AC lot

A suburban suite provides a private restroom, accessible entrances, and room for interior reconfiguration.

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Office Suite with Private Offices
Office Suite with Private Offices

1001 Craig Rd, Suite 200, Saint Louis, MO 63146

$13 SF/Yr
8,553 sqft

Well-appointed office suite with multiple private offices, training rooms, and conference rooms available for sublease.

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Flexible Professional Office Suite
Flexible Professional Office Suite

Saint Louis, MO 63146

$3,830/Mo
2.12 AC lot

Configured workspace includes private offices, a kitchenette, meeting space, and an open bullpen for collaborative operations.

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Professional Office Suite
Professional Office Suite

Saint Louis, MO 63146

$4,630/Mo
2.12 AC lot

White-box delivery, central air, and flexible suite sizing support a practical professional office setting.

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Flex Office Warehouse with Dock Door
Flex Office Warehouse with Dock Door

6108 Baumgartner Xing, Saint Louis, MO 63129

$7,250/Mo
5,000 sqft

5,000+ SF flex building features office space, warehouse area, kitchen area, and two restrooms with both dock-high and drive-in doors.

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Two-Level Office Units
Two-Level Office Units

3018 S Jefferson Avenue, St, Louis, MO 63118

$2,000/Mo
0.07 AC lot

Second- and third-floor space supports office, studio, and retail-oriented uses in Benton Park.

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Temperature-Controlled Office/Warehouse Suite
Temperature-Controlled Office/Warehouse Suite

11040 Lin Valle Dr, Saint Louis, MO 63123

$12 SF/Yr
1,075 sqft

Flex office/warehouse suite includes a private office and temperature-controlled space with an overhead door.

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Retail-Office Space with Highway Exposure
Retail-Office Space with Highway Exposure

12440 Lusher Road, Saint Louis, MO 63138

$12 SF/Yr
6,975 sqft

Retail/office building on major roadways with direct in-front Metro Transit access and strong Highway 367 traffic exposure.

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Office Space with Private Entrance
Office Space with Private Entrance

2117-2121 S Brentwood Blvd, Saint Louis, MO 63144

$20 SF/Yr
3,418 sqft

Two-level office suite offers private entrance, multiple offices, and built-in kitchen and breakroom areas.

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First-Floor Office Suite
First-Floor Office Suite

121 Hunter Ave, Saint Louis, MO 63124

$22 SF/Yr
1,540 sqft

Five private offices and a conference room create a practical multi-room professional workspace.

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Professional Office Suite
Professional Office Suite

201-2258 Schuetz Rd, Saint Louis, MO 63146

$3,830/Mo
2,702 sqft

Office suite includes four private offices, a kitchenette, and a conference/training room with open bullpen area.

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Class A Office Space
Class A Office Space

Saint Louis, MO 63102

$215 SF/Yr
348,675 sqft

Contiguous leasing options support a range of tenant sizes within a downtown office tower.

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White-Box Office Suite
White-Box Office Suite

205-2258 Schuetz Rd, Saint Louis, MO 63146

$4,630/Mo
3,268 sqft

Flexible professional office suite available in the 1,500 to 3,268 SF range with a 4.2/1,000 parking ratio.

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Prime St. Louis Commercial Space
Prime St. Louis Commercial Space

Saint Louis, MO 63102

$1,250/Mo
2,802 sqft

Versatile space suitable for retail, creative space, or restaurant use.

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Class A Office/Flex Space
Class A Office/Flex Space

Saint Louis, MO 63114

$10 SF/Yr
4,823 sqft

Office/flex building with contiguous space and highway visibility available for lease.

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Serviced Offices with Business Support at MO, St. Louis - Cedar Plaza. Contact us today to book a tour!
Serviced Offices with Business Support at MO, St. Louis - Cedar Plaza. Contact us today to book a tour!

5000 Cedar Plz St, Louis, MO 63128

16 available spaces from 11 to 1,973 sqft
$129-$15,680/Mo per office

Flexible workspace in MO, St. Louis - Cedar Plaza. Book a tour & get info

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Smart Workspace Options at MO, St. Louis - The Luxe on Lami. Contact us today to book a tour!
Smart Workspace Options at MO, St. Louis - The Luxe on Lami. Contact us today to book a tour!

1031 Lami St 63104 St, Louis, MO 63104

15 available spaces from 11 to 1,646 sqft
$129-$11,961/Mo per office

Flexible workspace in MO, St. Louis - The Luxe on Lami. Book a tour & get info

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Atrium Office with Railroad Views
Atrium Office with Railroad Views

904 S 4Th St, Unit 301, Saint Louis, MO 63103

$2,700/Mo
2,500 sqft

Top Floor Atrium Office with Railroad and Arch Views

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Saint Louis, MO Office Spaces Lease Rates & Market Statistics

Browse 189 Office Spaces for lease in Saint Louis, MO on Realmo, a commercial real estate marketplace serving the Saint Louis area. The current inventory totals 3,466,048 square feet of properties — an average of ~18,350 SF per listing.

Asking lease rates for Office Spaces in Saint Louis start at $8.06 SF/Yr, average $24.17 SF/Yr, and reach $215 SF/Yr at the top of the market. That's a 27x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $24.17 SF/Yr is 5% below the Missouri state average of $25.49 SF/Yr.

By space type, the market includes 142 office units, 33 office buildings and 22 medical office space listings — medical office space options typically offer the lowest entry point, while office buildings command the highest rates.

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