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    Des Peres, MO
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    Des Peres, MO Office Spaces for Lease

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    Saint Louis, MO Town And Country, MO Kirkwood, MO
    7 results
    MO, St. Louis - Craigshire Rd
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    Des Peres Office Space Available
    $19 SF/Yr
    2,173 SF
    Des Peres Office Space Available

    13100 Manchester Rd, Des Peres, MO

    Office space for rent in a convenient location.
    • Convenient Manchester/I‑270 Location
    • Abundant Parking
    • Common Corridors Recently Updated
    • Near Restaurants, West County Mall, Trader Joe’s & St. Louis Bread Company
    • Last Suite Available
    Updated: Nov 24, 2025
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    Des Peres Office Space Available
    $32 SF/Yr
    5,630 SF
    Des Peres Office Space Available

    13075 Manchester Road, Des Peres, MO 63131

    5,630 square feet of office space for lease.
    • 5,630 square feet of office space
    Updated: Nov 22, 2025
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    Retail and Office Space Available
    Contact for pricing
    Retail and Office Space Available

    Mixed-use building with retail, office, and lower level space.

    12005-12085 Manchester Rd, Des Peres, MO

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    Retail Space in Des Peres
    Contact for pricing
    Retail Space in Des Peres

    Retail space for lease anchored by Schnucks.

    12332 Manchester Road, Des Peres, MO 63131

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    Medical Office Space Available
    $28 SF/Yr
    13,515 SF
    Medical Office Space Available

    Medical office space for lease in Des Peres, Missouri.

    1000 Des Peres Rd, Des Peres, MO

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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 7 Active listings in Des Peres, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Renovated Office Building Near I-270
    $21 SF/Yr
    30,000 SF
    Renovated Office Building Near I-270

    Recently renovated 30,000 SF office building with ample parking.

    Town And Country, MO 63131

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    Frontenac Office Space for Rent
    $27 SF/Yr
    6,000 SF
    Frontenac Office Space for Rent

    Office suites available with hotel on-site and abundant parking.

    10369-10411 Clayton Rd, Frontenac, MO

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    Medical Office Space For Lease
    $30 SF/Yr
    4,831 SF
    Medical Office Space For Lease

    6,679 SF medical office space available February 1, 2024.

    10435 Clayton Rd, Frontenac, MO

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    Office Space with Open Floorplan
    $20 SF/Yr
    3,150 SF
    Office Space with Open Floorplan

    First floor office suite with open layout and amenities.

    660-670 Mason Ridge Center Dr, Town And Country, MO

    View details

    Similar Spaces for Sale in Des Peres, MO

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Des Peres Office Condo Suite
    $900,000
    2,000 SF
    Des Peres Office Condo Suite

    Office condo with high-end finishes and easy highway access.

    13421 Manchester Rd, Des Peres, MO

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    Class A Office Building Package
    Contact for pricing
    289,380 SF
    Class A Office Building Package

    Three Class A office buildings totaling 289,380 SF for sale.

    1650, 1630, 1610 Des Peres Road, Des Peres, MO 63131

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Collinsville Commercial Space For Lease
    $5,000/Mo
    5,000 SF
    Collinsville Commercial Space For Lease

    Versatile commercial space in Collinsville, available immediately.

    1902 Vandalia Street, Collinsville, IL 62234

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    High-Traffic Commercial Land in Rolla
    $7,500/Mo
    High-Traffic Commercial Land in Rolla

    0.61 acre commercial land in high-traffic area for lease.

    704 N Bishop Avenue, Rolla, MO 65401

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    Commercial Land on Kingshighway
    $5,500/Mo
    4,000 SF
    Commercial Land on Kingshighway

    Prime commercial land for lease in high-traffic Rolla location.

    1014 Kingshighway Street, Rolla, MO 65401

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    Commercial Land For Lease
    $12,500/Mo
    Commercial Land For Lease

    Prime commercial land for lease in high-traffic Rolla location.

    626 Bishop Avenue S, Rolla, MO 65401

    View details

    Des Peres, MO Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Des Peres, MO with 7 listings featured on our commercial real estate exchange. The current inventory includes 21,318 square feet of properties with an estimated lease value of $79 SF/Yr.

    Estimated lease rates for Office Spaces in Des Peres, MO begin at $19 SF/Yr, with an average of $26 SF/Yr and extend to $32 SF/Yr.
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    Most Searched ZIP Codes in Des Peres, MO

    • 63131

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