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    Des Peres, MO Office Spaces for Lease

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    Saint Louis, MO Kirkwood, MO Town And Country, MO Ballwin, MO Frontenac, MO Rock Hill, MO Fenton, MO Sunset Hills, MO
    6 properties
    Des Peres Office Space Available
    Updated: Nov 24, 2025
    Des Peres Office Space Available

    13100 Manchester Rd, Des Peres, MO

    $19 SF/Yr
    2,173 sqft
    Convenient Manchester/I‑270 Location
    Abundant Parking
    Common Corridors Recently Updated
    Near Restaurants, West County Mall, Trader Joe’s & St. Louis Bread Company
    Last Suite Available
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    Modern Office Space for Sublease
    Updated: Jul 4
    Modern Office Space for Sublease

    13421 Manchester Road, Des Peres, MO 63131

    Contact for pricing
    2,000 sqft
    Sublease available: 2,000 SF office space
    Office space term through 11/30/2028
    Building features modern, customizable office spaces with abundant natural light
    High‑end finishes and state‑of‑the‑art amenities
    Ample parking and professional business environment
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    Des Peres Office Space Available
    Des Peres Office Space Available

    13075 Manchester Road, Des Peres, MO 63131

    $32.50 SF/Yr
    5,630 sqft

    5,630 square feet of office space for lease.

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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Retail and Office Space Available
    Retail and Office Space Available

    12005-12085 Manchester Rd, Des Peres, MO

    Contact for pricing
    116 sqft

    Mixed-use building with retail, office, and lower level space.

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    Retail Space in Des Peres
    Retail Space in Des Peres

    12332 Manchester Road, Des Peres, MO 63131

    Contact for pricing

    Retail space for lease anchored by Schnucks.

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    Medical Office Space Available
    Medical Office Space Available

    1000 Des Peres Rd, Des Peres, MO

    $28 SF/Yr
    13,515 sqft

    Medical office space for lease in Des Peres, Missouri.

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    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 6 Active listings in Des Peres, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Renovated Office Building Near I-270
    Renovated Office Building Near I-270

    Town And Country, MO 63131

    $21 SF/Yr
    30,000 sqft

    Recently renovated 30,000 SF office building with ample parking.

    View details
    West County Office Space Available
    West County Office Space Available

    13515 Barrett Parkway Dr, Ballwin, MO

    $15 SF/Yr
    15,241 sqft

    Prime location with renovated common areas and building signage.

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    Renovated Office Space Available
    Renovated Office Space Available

    13523 Barrett Pkwy Dr, Ballwin, MO

    $20.50 SF/Yr
    11,201 sqft

    Office space for rent with renovated lobbies and common areas.

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    Office Space with Open Floorplan
    Office Space with Open Floorplan

    660-670 Mason Ridge Center Dr, Town And Country, MO

    $20 SF/Yr
    3,150 sqft

    First floor office suite with open layout and amenities.

    View details

    Similar Spaces for Sale in Des Peres, MO

    Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

    Des Peres Office Condo Suite
    Des Peres Office Condo Suite

    13421 Manchester Rd, Des Peres, MO

    $900,000
    2,000 sqft 3.45 AC lot

    Office condo with high-end finishes and easy highway access.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Class A Office Suite with Bullpen
    Class A Office Suite with Bullpen

    1902 Vandalia Street, Collinsville, IL 62234

    $5,000/Mo

    Recently built office space with private offices, bullpen, and modern amenities for professional teams.

    View details
    Office Development Land For Lease
    Office Development Land For Lease

    1323 Strawfloor Drive, Jonesboro, AR 72401

    Contact for pricing
    4,000 sqft

    2.43 acres for office development with build-to-suit opportunity.

    View details
    Plainfield Commercial Land For Rent
    Plainfield Commercial Land For Rent

    SW corner of Rte 59 & Fraser Road, Plainfield, IL 60586

    Contact for pricing

    6.491 acre commercial land available for rent in Plainfield, IL.

    View details
    Joplin Commercial Land For Lease
    Joplin Commercial Land For Lease

    2914&2920 E 22nd Street, Joplin, MO 64804

    $20/Mo
    5,000 sqft

    Versatile commercial land with potential for customized building.

    View details

    Des Peres, MO Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Des Peres, MO with 6 listings featured on our commercial real estate exchange. The current inventory includes 21,318 square feet of properties with an estimated lease value of $79.50 SF/Yr.

    Estimated lease rates for Office Spaces in Des Peres, MO begin at $19 SF/Yr, with an average of $26.50 SF/Yr and extend to $32.50 SF/Yr.
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