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    Des Peres, MO Office Properties & Spaces for Lease

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    Saint Louis, MO Louis, MO Kansas City, MO
    Des Peres Office Space Available
    $19 SF/Yr
    2,173 SF

    Des Peres Office Space Available

    13100 Manchester Rd, Des Peres, MO

    Office space for rent in a convenient location.

    • Convenient Manchester/I‑270 Location
    • Abundant Parking
    • Common Corridors Recently Updated
    • Near Restaurants, West County Mall, Trader Joe’s & St. Louis Bread Company
    • Last Suite Available
    Updated: Nov 24, 2025
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    Retail and Office Space Available
    Contact for pricing

    Retail and Office Space Available

    12005-12085 Manchester Rd, Des Peres, MO

    Mixed-use building with retail, office, and lower level space.

    • Mixed‑use building with retail, office, and lower level space
    • Located on Manchester Road
    • High traffic volume: 25,771 VPD
    • Close proximity to I‑270 and West County Center
    • Near major retailers: Nordstrom, Macy’s, Dick’s
    Updated: Apr 2, 2025
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    Retail Space in Des Peres
    Contact for pricing

    Retail Space in Des Peres

    Retail space for lease anchored by Schnucks.

    12332 Manchester Road, Des Peres, MO 63131
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    Medical Office Space Available
    $28 SF/Yr
    13,515 SF

    Medical Office Space Available

    Medical office space for lease in Des Peres, Missouri.

    1000 Des Peres Rd, Des Peres, MO
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    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 4 Active listings in Des Peres, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Renovated Office Building Near I-270
    $21 SF/Yr
    30,000 SF

    Renovated Office Building Near I-270

    Recently renovated 30,000 SF office building with ample parking.

    Town And Country, MO 63131
    View details
    Office Space with Building Amenities
    $28 SF/Yr
    19,982 SF

    Office Space with Building Amenities

    Office space featuring 24/7 access and on-site management.

    1245 J J Kelley Memorial Dr, Saint Louis, MO
    View details
    Office Space with Open Floorplan
    $20 SF/Yr
    3,150 SF

    Office Space with Open Floorplan

    First floor office suite with open layout and amenities.

    660-670 Mason Ridge Center Dr, Town And Country, MO
    View details
    Class A Office Campus
    Contact for pricing
    289,245 SF

    Class A Office Campus

    Class A office campus with suites available for lease.

    Saint Louis, MO 63131
    View details

    Explore Similar Spaces for Sale in Des Peres, MO

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Des Peres Office Condo Suite
    $900,000
    2,000 SF

    Des Peres Office Condo Suite

    Office condo with high-end finishes and easy highway access.

    13421 Manchester Rd, Des Peres, MO
    View details
    Class A Office Building Package
    Contact for pricing
    289,380 SF

    Class A Office Building Package

    Three Class A office buildings totaling 289,380 SF for sale.

    1650, 1630, 1610 Des Peres Road, Des Peres, MO 63131
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Collinsville Commercial Space For Lease
    $5,000 /Mo
    5,000 SF

    Collinsville Commercial Space For Lease

    Versatile commercial space in Collinsville, available immediately.

    1902 Vandalia Street, Collinsville, IL 62234
    View details
    Cleared Lot in St Clair
    $1.00 SF/Yr

    Cleared Lot in St Clair

    1.5-acre cleared lot zoned for general commercial use.

    Saint Clair, MO 63077
    View details
    High-Traffic Commercial Land in Rolla
    $7,500 /Mo

    High-Traffic Commercial Land in Rolla

    0.61 acre commercial land in high-traffic area for lease.

    704 N Bishop Avenue, Rolla, MO 65401
    View details
    Commercial Land on Kingshighway
    $5,500 /Mo
    4,000 SF

    Commercial Land on Kingshighway

    Prime commercial land for lease in high-traffic Rolla location.

    1014 Kingshighway Street, Rolla, MO 65401
    View details

    Des Peres, MO Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Des Peres, MO with 4 listings featured on our commercial real estate exchange. The current inventory includes 375,617,880 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Des Peres, MO begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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    Most Searched ZIP Codes in Des Peres, MO

    • 63131

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