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    Clayton, MO Office Units for Lease

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    Saint Louis, MO Louis, MO Kansas City, MO
    28 results
    Clayton Office Space Available Now
    $30 SF/Yr
    4,288 SF

    Clayton Office Space Available Now

    231 S Bemiston Ave, Clayton, MO

    Former law firm space with elevator exposure and tenant amenities.

    • Prime location: Very short walking distance from the Clayton Metrolink and easy access to Forest Park Parkway and Interstate 170.
    • Tenant‑exclusive amenities: Includes a bike room, fitness center, lockers, and showers.
    • On‑site conveniences: Features an on‑site café, grab‑n‑go, and tenant lounge.
    • Ample office space: Offers nine private offices, two conference rooms, a break room, and a work room.
    • Attached parking garage: Includes a five‑level garage with an automated access system.
    Updated: Aug 14, 2025
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    Professionally Managed Office Space Available
    $25 SF/Yr
    2,709 SF

    Professionally Managed Office Space Available

    8151 Clayton Rd, Clayton, MO

    Office space for lease with covered parking and convenient location.

    • Prime location across from St. Louis Galleria
    • Easy access to I‑64/Hwy 40 & I‑170
    • Full service lease at $25.00 PSF
    • Free attached covered parking
    • Professionally managed office building
    Updated: Nov 25, 2025
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    Clayton Office Space For Rent
    $26 SF/Yr
    3,346 SF

    Clayton Office Space For Rent

    Eleven-story office building in Clayton with recent renovations.

    222 S Central Ave, Clayton, MO
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    Downtown Clayton Office Space Available
    $29 SF/Yr
    1,737 SF

    Downtown Clayton Office Space Available

    Office space for lease in downtown Clayton with amenities.

    150 N Meramec Ave, Clayton, MO
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    Clayton Office Space For Rent
    $14 SF/Yr
    350 SF

    Clayton Office Space For Rent

    Office spaces in the heart of Clayton near I-170 & I-64/40.

    30-44 N Brentwood Blvd, Clayton, MO
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    Class A Office Space Available
    $45 SF/Yr
    27,666 SF

    Class A Office Space Available

    High-end office space with many amenities and ample parking.

    7700 Forsyth Blvd, Clayton, MO
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    Downtown Clayton Office Space Available
    $29 SF/Yr
    2,372 SF

    Downtown Clayton Office Space Available

    Office space for rent in downtown Clayton, Missouri.

    165 N Meramec Ave, Clayton, MO
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    Downtown Clayton Office Space Available
    $28 SF/Yr
    10,007 SF

    Downtown Clayton Office Space Available

    Office space in downtown Clayton with convenient access and amenities.

    168 N Meramec Ave, Clayton, MO
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    Clayton CBD Office Space
    $31 SF/Yr
    1,464 SF

    Clayton CBD Office Space

    Move-in ready office suites in central Clayton location.

    7777 Bonhomme Ave, Clayton, MO
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    Clayton Office Space Available
    $24 SF/Yr
    3,270 SF

    Clayton Office Space Available

    Office space available for lease in Clayton, Missouri.

    8251 Maryland Ave, Clayton, MO
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    Clayton Office Space For Rent
    $24 SF/Yr
    3,305 SF

    Clayton Office Space For Rent

    3,305 SF office space available in Clayton, Missouri.

    8301 Maryland Ave, Clayton, MO
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    Clayton Office Space For Rent
    $31 SF/Yr
    7,441 SF

    Clayton Office Space For Rent

    7,441 square foot office space available for lease.

    135 N Meramec Ave, Clayton, MO
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    Energy Efficient Clayton Office Space
    Contact for pricing

    Energy Efficient Clayton Office Space

    Sophisticated office space in a central Clayton location.

    7733 Forsyth Boulevard Suite 1100, Clayton, MO 63105
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    Renovated Office Space in Clayton
    $26 SF/Yr
    1,993 SF

    Renovated Office Space in Clayton

    Multiple suites available in a recently renovated building.

    7711 Bonhomme Ave, Clayton, MO
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    Clayton Office Space For Rent
    $31 SF/Yr
    45,777 SF

    Clayton Office Space For Rent

    Office space available in Clayton, Missouri with multiple amenities.

    7701 Forsyth Blvd, Clayton, MO
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    Clayton Office Space For Rent
    $31 SF/Yr
    39,547 SF

    Clayton Office Space For Rent

    Office space available with conferencing center and fitness center.

    7733 Forsyth Blvd, Clayton, MO
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    Clayton Office Space For Rent
    $32 SF/Yr
    4,494 SF

    Clayton Office Space For Rent

    Office space for rent in Clayton, Missouri.

    120 S Central Ave, Clayton, MO
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    Prime St. Louis Office Space
    Contact for pricing

    Prime St. Louis Office Space

    Modern office space in a vibrant St. Louis location.

    212 S Central Ave, Clayton, MO 63105
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    Upscale Office Space Available
    $30 SF/Yr
    6,125 SF

    Upscale Office Space Available

    Premium office space with amenities in Clayton, Missouri.

    8000 Maryland Ave, Clayton, MO
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    Downtown Clayton Office Space Available
    $24 SF/Yr
    4,500 SF

    Downtown Clayton Office Space Available

    Office space for rent in downtown Clayton near amenities.

    7808-7810 Forsyth Blvd, Clayton, MO
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    Downtown Clayton Office Space
    $1,400/Mo
    680 SF

    Downtown Clayton Office Space

    Office space for rent in downtown Clayton, Missouri.

    7800 Bonhomme Ave, Clayton, MO
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    Forsyth Blvd Office Space Available
    $45 SF/Yr
    20,000 SF

    Forsyth Blvd Office Space Available

    Office space available with covered parking and modern amenities.

    7676 Forsyth Blvd, Clayton, MO
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    Clayton Office Space Available
    Contact for pricing
    634 SF

    Clayton Office Space Available

    Office suites available in Clayton, move-in ready, renovated common areas.

    130 S Bemiston Ave, Clayton, MO
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    Class A Office Tower Clayton
    $33 SF/Yr
    1,861 SF

    Class A Office Tower Clayton

    Modern office space with comprehensive amenities in Clayton, Missouri.

    101 S Hanley Rd, Clayton, MO
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    Clayton, MO Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Clayton, MO with 28 listings featured on our commercial real estate exchange. The current inventory includes 3,281,810,400 square feet of properties with an estimated lease value of $280 SF/Yr.

    Estimated lease rates for Office Units in Clayton, MO begin at $14 SF/Yr, with an average of $28 SF/Yr and extend to $45 SF/Yr.
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    Most Searched ZIP Codes in Clayton, MO

    • 63105
    • 63117

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