Advertise
    Cape Girardeau, MO
    Office Building

    Cape Girardeau, MO Office Buildings for Lease

    Notify Me
    List
    Map
    Scott City, MO Jackson, MO
    Renovated Office and Storefront Building
    Updated: Jul 1, 2025
    Renovated Office and Storefront Building

    230 N Sprigg Street, Cape Girardeau, MO 63701

    $2,500/Mo
    2,937 sqft · $10 SF/Yr
    Massive brick building (approx. 3,000 sq ft) with renovated space
    Road frontage on N Sprigg St in a downtown, high‑traffic area
    BRAND NEW A/C, roof, gutters, flooring, fixtures, bathrooms, kitchenette, siding, and newly tuckpointed exterior
    Forced air heating with central air and electric cooling
    Public utilities: public water and public sewer
    View details
    Downtown Office Building For Lease
    Updated: Mar 5
    Downtown Office Building For Lease

    18 N. Main, Cape Girardeau, MO 63701

    $8,558/Mo
    13,694 sqft · $7 SF/Yr
    13,694 SF Single‑Level Office Building
    Located in Historic Downtown Cape Girardeau on the Riverfront
    Suitable for Various Uses & Businesses
    Adjacent to Municipal Off‑Street Parking Lot
    Multiple Entrances From Two Separate Streets
    View details
    Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 2 Active listings in Cape Girardeau, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

    Office buildings for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office-Warehouse Flex Building
    Office-Warehouse Flex Building

    3530 Park Plaza Road, Paducah, KY 42001

    $4,995/Mo
    11,270 sqft · $5 SF/Yr

    Flex office and insulated, heated warehouse space with two overhead doors for flexible business operations.

    View details
    Multi-Level Office and Retail Building
    Multi-Level Office and Retail Building

    1016 Main Street, Benton, KY 42025

    $2,500/Mo
    8,360 sqft · $3 SF/Yr

    Flexible multi-level space with multiple rooms, interior access, and a secure basement vault for storage or protection.

    View details
    Office Suite Rental
    Office Suite Rental

    100 Fountain Ave Suite 205, Paducah, KY 42001

    $900/Mo
    17,500 sqft · $0.62 SF/Yr

    For rent office suite in Paducah with AU zoning and a 1.03-acre site.

    View details
    Multi-Level Office Building with Vault
    Multi-Level Office Building with Vault

    1016 Main St, Benton, KY 42025

    $2,500/Mo

    Flexible multi-level space with multiple rooms and a large secure basement vault for storage or shelter use.

    View details

    Similar Spaces for Sale in Cape Girardeau, MO

    Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

    Renovated Mid-Century Office Building
    Renovated Mid-Century Office Building

    429 N Broadview Street, Cape Girardeau, MO 63701

    $1,690,000
    15,831 sqft · 1.37 AC lot

    Renovated 1960s office building with event space, overhead doors, and gated rear parking for flexible operations.

    View details
    Renovated Downtown Office and Retail Building
    Renovated Downtown Office and Retail Building

    230 N Sprigg Street, Cape Girardeau, MO 63701

    $239,900
    2,937 sqft · 0.25 AC lot

    Renovated commercial building on a high-traffic downtown corridor, offering flexible space for offices or storefront services.

    View details
    Well-Kept Commercial Building with Parking
    Well-Kept Commercial Building with Parking

    2357 Rust Avenue, Cape Girardeau, MO 63703

    $199,900
    0.57 AC lot

    Versatile 1,800-square-foot commercial building with easy access and ample parking in Cape Girardeau, Missouri.

    View details
    Updated Office Building For Sale
    Updated Office Building For Sale

    824 Independence Street, Cape Girardeau, MO 63703

    $350,000
    0.42 AC lot

    Well-maintained office building with high visibility and ample parking.

    View details
    Flex Space with Riverfront Access
    Flex Space with Riverfront Access

    308 N Main Street, Cape Girardeau, MO 63701

    $475,000
    0.50 AC lot

    Flexible riverfront building with multiple overhead doors, loading dock, and parking on both sides for varied commercial uses.

    View details
    Two-Level Office Building For Sale
    Two-Level Office Building For Sale

    10 Doctors Park, Cape Girardeau, MO 63703

    $815,000
    9,857 sqft · 0.44 AC lot

    9,857 SF office building with multiple offices and restrooms.

    View details
    Renovated Commercial Building on Sprigg
    Renovated Commercial Building on Sprigg

    230 N Sprigg Street, Cape Girardeau, MO 63701

    $239,900
    2,937 sqft · 0.25 AC lot

    Renovated commercial space with high visibility and income potential.

    View details
    Renovated Mid-Century Office Building
    Renovated Mid-Century Office Building

    429 N Broadview Street, Cape Girardeau, MO 63701

    $1,690,000
    15,831 sqft

    Updated office building with multiple private offices, conference rooms, and an event space with bar and projection screen.

    View details
    Downtown Office Building For Sale
    Downtown Office Building For Sale

    18 N. Main, Cape Girardeau, MO 63701

    $899,900
    13,694 sqft

    13,694 SF office building in historic downtown Cape Girardeau.

    View details
    Professional Office Complex For Sale
    Professional Office Complex For Sale

    240-276 S. Mount Auburn Road, Cape Girardeau, MO 63703

    Contact for pricing
    6.78 AC lot

    Professional office complex with parking near I-55, hotels, restaurants.

    View details
    13,694 SF Single-Level Office Building
    13,694 SF Single-Level Office Building

    18 Main St, Cape Girardeau, MO 63701

    $899,900
    13,694 sqft

    Single-level office building suitable for various uses and businesses.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Class A Office Suite with Bullpen
    Class A Office Suite with Bullpen

    1902 Vandalia Street, Collinsville, IL 62234

    $5,000/Mo

    Recently built office space with private offices, bullpen, and modern amenities for professional teams.

    View details
    Office Development Land For Lease
    Office Development Land For Lease

    1323 Strawfloor Drive, Jonesboro, AR 72401

    Contact for pricing
    4,000 sqft

    2.43 acres for office development with build-to-suit opportunity.

    View details
    High-Traffic Commercial Land in Rolla
    High-Traffic Commercial Land in Rolla

    704 N Bishop Avenue, Rolla, MO 65401

    $7,500/Mo

    0.61 acre commercial land in high-traffic area for lease.

    View details
    Corner Lot on Highway 72
    Corner Lot on Highway 72

    30472 Highway 72, Madison, AL 35756

    $5,000/Mo
    1,875 sqft · $32 SF/Yr

    1.7 acre corner lot zoned for commercial, medical, residential.

    View details

    Cape Girardeau, MO Office buildings Market Trends and Statistics

    Explore Office buildings leasing options in Cape Girardeau, MO with 2 listings featured on our commercial real estate exchange. The current inventory includes 16,631 square feet of properties with an estimated lease value of $17 SF/Yr.

    Estimated lease rates for Office buildings in Cape Girardeau, MO begin at $7 SF/Yr, with an average of $8 SF/Yr and extend to $10 SF/Yr.
    List
    Map

    Popular Searches in Cape Girardeau, MO

    Popular Categories

    Most Searched ZIP Codes in Cape Girardeau, MO

    • 63701

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!