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    Hyannis, MA
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    Hyannis, MA Mixed-use Properties for Sale

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    West Yarmouth, MA Sandwich, MA Mashpee, MA
    7 results
    Restaurant Space in Downtown Hyannis
    $499,000
    2,256 SF

    Restaurant Space in Downtown Hyannis

    517 Main Street, Hyannis, MA 02601

    Turnkey restaurant with flexible space in the heart of Hyannis.

    • Prime Downtown Main Street location in Hyannis, close to attractions, ferries, the airport, shopping, and entertainment.
    • Licensed restaurant space with 70 indoor seats and 24 outdoor patio seats.
    • Fully equipped commercial kitchen ready for immediate use.
    • Remodeled second floor with flexible space for storage, office, or a one‑bedroom residential unit.
    • Utilities include natural gas heating, wall unit cooling, and public water/sewer.
    Updated: Feb 23
    View details
    Hyannis Commercial Space For Sale
    $1,999,000
    13,242 SF

    Hyannis Commercial Space For Sale

    338 Main Street, Hyannis, MA 02601

    Prime commercial space in downtown Hyannis with diverse tenant mix.

    • Great Location near shopping
    • Newly renovated kitchen
    • Features a spacious backyard
    • Close to public transportation
    • Includes a detached garage
    Updated: Dec 1, 2025
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    Downtown Hyannis Mixed-Use Property
    $1,285,000
    4,032 SF

    Downtown Hyannis Mixed-Use Property

    Turnkey mixed-use property with buildable lot in downtown Hyannis.

    574 Main Street, Hyannis, MA 02601
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    Downtown Hyannis Commercial Space
    $2,195,000
    13,424 SF

    Downtown Hyannis Commercial Space

    Prime commercial space in downtown Hyannis with diverse tenant mix.

    Hyannis, MA 2601
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    Downtown Hyannis Commercial Space
    $2,195,000
    13,242 SF

    Downtown Hyannis Commercial Space

    Prime commercial space in thriving downtown Hyannis business district.

    338 Main, Hyannis, MA 2601
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    Hyannis Mixed-Use Building For Sale
    $329,000

    Hyannis Mixed-Use Building For Sale

    Duplex in high-traffic area, ideal for investors or owner-users.

    705 Main St, Barnstable, MA 2601
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    Hyannis Mixed-Use Investment Opportunity
    $379,000
    1,380 SF

    Hyannis Mixed-Use Investment Opportunity

    Commercial/Residential building in Hyannis with established business and rental income.

    705 Main St, Barnstable, MA 2601
    View details
    Based on your search, we've compiled 111 Potential Opportunities for your consideration. Besides 7 Active listings in Hyannis, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 96 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Property in Yarmouth Port
    $579,000
    929 SF

    Versatile Property in Yarmouth Port

    Live, work, and play in a desirable location.

    194 Route 6A, Yarmouth Port, MA 02675
    View details
    Falmouth Commercial Property with Development Potential
    $3,950,000
    6,177 SF

    Falmouth Commercial Property with Development Potential

    Two buildings with excess land for commercial development.

    876 East Falmouth Hwy, Falmouth, MA 2536
    View details
    Multi-Use Property in Yarmouth Port
    $1,699,000
    4,414 SF

    Multi-Use Property in Yarmouth Port

    Three-unit property with office spaces and a residential house.

    927-935 MA-6A, Yarmouth Port, MA 02675
    View details
    Brewery, Restaurant, and Development Opportunity
    $3,950,000
    6,177 SF

    Brewery, Restaurant, and Development Opportunity

    Falmouth property with brewery, restaurant, cottage, and development potential.

    876 East Falmouth Hwy, Falmouth, MA 2536
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Oak Bluffs Mixed-Use Development Opportunity
    $599,000

    Oak Bluffs Mixed-Use Development Opportunity

    B1-zoned parcel with approved plans for mixed-use development.

    112 Dukes County, Marthas Vineyard, MA 2557
    View details
    1.14 Acre Mixed-Use Land
    $600,000
    1.14 Acres

    1.14 Acre Mixed-Use Land

    1.14 acres in Eastham, MA, suitable for various developments.

    20 Oak Road, Eastham, MA 2642
    View details
    Land Near Hanson MBTA Station
    $950,000
    2.05 Acres

    Land Near Hanson MBTA Station

    2.05 acres of commercial land near MBTA station.

    1011-1057 Main St, Hanson, MA 2341
    View details
    Tiverton Commercial Land For Sale
    $400,000
    0.37 Acres

    Tiverton Commercial Land For Sale

    Prime 0.37-acre lot at high-traffic intersection, ideal for development.

    2388 Main Road, Tiverton, RI 02878
    View details

    Off-Market Properties in Hyannis, MA

    Consider similar Off-Market properties in Hyannis, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    231 Sea St

    231 Sea St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,198 SF
    Value Estimation
    $580,000
    231 Sea St, Hyannis, MA 02601-4573
    View details
    255 Main St

    255 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 11,627 SF
    Value Estimation
    $3,835,000
    255 Main St, Hyannis, MA 02601-4067
    View details
    356 Ss St

    356 Ss St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.27 Acres
    Value Estimation
    $590,000
    356 Ss St, Hyannis, MA 02601-5404
    View details
    17 School St

    17 School St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,168 SF
    Value Estimation by Request
    17 School St, Hyannis, MA 02601-3117
    View details
    606 Main St

    606 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.29 Acres
    Value Estimation
    $2,000,000
    606 Main St, Hyannis, MA 02601-5432
    View details
    645 Main St

    645 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.14 Acres
    Value Estimation
    $545,000
    645 Main St, Hyannis, MA 02601-5458
    View details
    1481 Iyannough Rd

    1481 Iyannough Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 6,666 SF
    Value Estimation
    $1,325,000
    1481 Iyannough Rd, Hyannis, MA 02601-1872
    View details
    675 Main St

    675 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,837 SF
    Value Estimation by Request
    675 Main St, Hyannis, MA 02601-5465
    View details
    605 Main St

    605 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.16 Acres
    Value Estimation
    $740,000
    605 Main St, Hyannis, MA 02601-5463
    View details
    517 Main St

    517 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,256 SF
    Value Estimation by Request
    517 Main St, Hyannis, MA 02601-5407
    View details
    246 Nn St

    246 Nn St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,200 SF
    Value Estimation
    $700,000
    246 Nn St, Hyannis, MA 02601-3850
    View details
    123 Old Yarmouth Rd

    123 Old Yarmouth Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 736 SF
    Value Estimation by Request
    123 Old Yarmouth Rd, Hyannis, MA 02601-2013
    View details
    740 Bearses Way

    740 Bearses Way

    OFFICE/RESIDENTIAL (MIXED USE) • 0.69 Acres
    Value Estimation by Request
    740 Bearses Way, Hyannis, MA 02601-2258
    View details
    574 Main St

    574 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,032 SF
    Value Estimation
    $645,000
    574 Main St, Hyannis, MA 02601-5410
    View details
    561 Main St Sta, Unit A

    561 Main St Sta, Unit A

    OFFICE/RESIDENTIAL (MIXED USE) • 3,648 SF
    Value Estimation
    $790,000
    561 Main St Sta, Hyannis, MA 02601-5414
    View details
    497 Main St

    497 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,833 SF
    Value Estimation
    $1,025,000
    497 Main St, Hyannis, MA 02601-5407
    View details
    282 Main St

    282 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,241 SF
    Value Estimation
    $745,000
    282 Main St, Hyannis, MA 02601-4003
    View details

    Hyannis, MA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 103 mixed-use properties for sale in Hyannis, MA, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 50,991 square feet of properties for sale, with an estimated market value of $10,552,000.

    Sale prices for multi use buildings in Hyannis, MA start at $379,000, averaging $1,507,428, and reaching up to $2,195,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    6-Month New Listing Trend

    Monthly new listing volume vs. 6-month average in Hyannis.

    Demographics Overview

    Population 16K
    Population Growth (5Y) +5.6%
    Median Household Income $62,989
    College Educated 38.6%

    High-Yield Neighborhoods for Strategic Investment

    Identify Hyannis submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    02601 $1.7M

    Taxes & Financing

    Tax Rate (average for all types) 0.93%
    Property Tax per SF $7.28 per sq ft
    Tax Rate vs County Average 0.23 pp above county avg
    Average Loan-to-Value 65.0%

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