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Hyannis, MA Office Spaces for Sale

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Brewster, MA West Yarmouth, MA Sandwich, MA Mashpee, MA Dennis Port, MA Falmouth, MA West Harwich, MA Sagamore, MA
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Two-Story Restaurant with Patio
Updated: Feb 23
Two-Story Restaurant with Patio

517 Main Street, Hyannis, MA 02601

$450,000
2,256 sqft 0.07 AC lot
First floor includes a licensed 70‑seat dining space plus 24 outdoor patio seats
Full commercial kitchen included and ready for a restaurant concept
Second floor is recently remodeled with flexible space plus 1‑bedroom, 1‑bath residential unit option
Utilities include phone available; water source is public and sewer is public sewer
Heating is forced air with natural gas; cooling includes wall unit(s)
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This listing looks promising.

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517 Main Street, Hyannis, MA 02601

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Multi-Use Commercial Building
Updated: Jun 22
Multi-Use Commercial Building

491 Iyannough Road, Hyannis, MA 02601

$1,300,000
3,215 sqft 0.36 AC lot
3,215 sq ft commercial property with a spacious main level plus second‑floor office/storage and a full basement
Garage/warehouse included for added commercial flexibility
High‑visibility corner location at the Airport Rotary, abutting Staples Plaza at the intersection of Route 28, Route 132 and Barnstable Road
Across from Cape Cod Gateway Airport, with access to nearby Downtown Hyannis
Utilities: public water and public sewer
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Multi-Tenant Medical Office Building
Multi-Tenant Medical Office Building

765 Attucks Lane, Hyannis, MA 02601

$3,495,000
17,713 sqft 2.32 AC lot

Multi-story, multi-tenant office facility with elevator access and ample surface parking on a waterfront-view site.

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West Barnstable Commercial-Residential Opportunity
West Barnstable Commercial-Residential Opportunity

1049 Main Street, West Barnstable, MA 02668

$1,450,000
6,684 sqft 1.09 AC lot

Multi-use property with business and residential potential on Route 6A.

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Medical Office with Attached Residence
Medical Office with Attached Residence

West Barnstable, MA 02668

$1,450,000
6,400 sqft

Updated 6,400 sq. ft. medical office with post-and-beam character, plus an attached residence for flexible live-work use.

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Turnkey Mixed-Use Property with Parking
Turnkey Mixed-Use Property with Parking

712 Main Street, Hyannis, MA 02601

$2,000,000
3,415 sqft 0.25 AC lot

Fully renovated in 2021 with nine rented salon suites, second-floor apartment, and parking for eight on-site.

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Hyannis Commercial Condominium For Sale
Hyannis Commercial Condominium For Sale

68 Center Street, Hyannis, MA 02601

$545,000
2,790 sqft 2.08 AC lot

Commercial condominium in Hyannis, ideal for investment or relocation.

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Downtown Hyannis Office Building
Downtown Hyannis Office Building

Hyannis, MA 02601

$1,999,000
8,000 sqft

Recently renovated professional office building with central AC, gas heat, and shared space across multiple floors.

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Renovated First-Floor Office Condo
Renovated First-Floor Office Condo

68 Center Street, Hyannis, MA 02601

$795,000
5,790 sqft

Modern first-floor condo unit with renovated interiors, kitchen, and two half baths, supported by flexible zoning.

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Fully Leased Professional Office Building
Fully Leased Professional Office Building

243 South Street, Hyannis, MA 02601

$775,000
2,766 sqft 0.53 AC lot

Fully occupied professional office building on a 0.53-acre parcel, built in 1910 and updated in 1984.

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Turnkey Fully Leased Office Building
Turnkey Fully Leased Office Building

Hyannis, MA 02601

$775,000
2,766 sqft 0.53 AC lot

Fully occupied professional office building on a 0.53-acre parcel with established long-term radio station tenant.

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Front-Entrance Flex Office Unit
Front-Entrance Flex Office Unit

270 Communication Way, Hyannis, MA 02601

$299,000
1,414 sqft

End unit with multiple offices, many windows, and a rear overhead door for flexible business and storage use.

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Second-Floor Office Condo in Bayberry Square
Second-Floor Office Condo in Bayberry Square

1645 Falmouth Road, Centerville, MA 02632

$97,000
479 sqft

Light, bright second-floor office unit with central air and vaulted ceilings, plus attic storage and manageable monthly condo costs.

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Multi-Tenant Office Building
Multi-Tenant Office Building

765 Attucks Lane, Hyannis, MA 02601

$3,495,000
17,713 sqft 2.81 AC lot

Multi-tenant office building on a waterfront-pond view site with parking and elevator access near major Cape Cod services.

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Modern Condo Unit in Hyannis
Modern Condo Unit in Hyannis

68 Center Street Ste 17, Hyannis, MA 02601

$795,000
5,790 sqft

Renovated 2,895 sq ft condo in Hyannis business district.

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Historic Hyannis Main Street Property
Historic Hyannis Main Street Property

615-617 Main St, Hyannis, MA

$849,000
2,228 sqft 0.54 AC lot

Prime location suitable for retail, restaurant, or office use.

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Commercial Condominium in Hyannis
Commercial Condominium in Hyannis

68 Center Street #19, Hyannis, MA 02601

$545,000
2,787 sqft

Commercial condominium for sale or lease in Hyannis, MA.

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Downtown Professional Office Space
Downtown Professional Office Space

45 Barnstable Road, Hyannis, MA 02601

Contact for pricing
682 sqft

Professional office space with private off-street parking and signage opportunities on a busy corridor.

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Restaurant and Flexible Live-Work Space
Restaurant and Flexible Live-Work Space

517 Main Street, Barnstable, MA 02601

$450,000
2,256 sqft

First-floor restaurant includes a licensed 70-seat dining area, commercial kitchen, and 24-seat outdoor patio.

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Centerville Office Unit For Sale
Centerville Office Unit For Sale

1645 Falmouth Road STE 3A, Centerville, MA 02632

$97,000
479 sqft

Prime office location with Route 28 visibility in Centerville.

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3,024 SF Flex Condo Unit
3,024 SF Flex Condo Unit

Barnstable, MA 02601

$685,000
3,024 sqft 0.07 AC lot

3,024 SF Flex Condo Prime Location on Main Street in Hyannis

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Multi-Tenant Convenience and Office Property
Multi-Tenant Convenience and Office Property

804 Main Street, Barnstable, MA 02655

$5,900,000
19,304 sqft 1.00 AC lot

One-acre mixed-use site with a Speedway convenience store, Dunkin Donuts, and a multi-tenant office building.

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Commercial Condo in Hyannis Center
Commercial Condo in Hyannis Center

68 Center Street, Hyannis, MA 02601

$525,000
2,787 sqft

First-floor commercial condo with flexible layout and convenient location.

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Office
Office

1436 Iyannough Road, Hyannis, MA 02601

$1,545,000
5,400 sqft

Office buildings · 5,400 SF

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Hyannis, MA Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Hyannis, MA, showcased through 26 active listings on our real estate platform. These investment opportunities span a total of 129,083 square feet of properties for sale, with an estimated market value of $31,891,000.

Sale prices for office spaces in Hyannis, MA start at $97,000, averaging $1,275,640, and reaching up to $5,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 23
Medical Office Space 7
Office buildings 6

Demographics Overview

Population 16K
Population Growth (5Y) +5.6%
Median Household Income $62,989
College Educated 38.6%

High-Yield Neighborhoods for Investment

Identify Hyannis submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
02601 $1.2M

Taxes & Financing

Tax Rate (average for all types) 0.93%
Property Tax per SF $7.28 per SF
Tax Rate vs County Average 0.23 pp above county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Barnstable County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Barnstable County

Office

Residential Income

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