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    Hyannis, MA
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    Hyannis, MA Commercial Real Estate for Lease

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    Yarmouth, MA Mashpee, MA Sandwich, MA
    22 results
    Prime Hyannis Commercial Property
    $3,000/Mo
    2,168 SF

    Prime Hyannis Commercial Property

    17 School Street, Hyannis, MA 02601

    Versatile commercial space in downtown Hyannis, multiple use potential.

    • Prime downtown Hyannis location with high visibility.
    • Versatile 1,464 sq ft commercial space suitable for professional, medical, or business uses.
    • Off‑street parking for staff and clients.
    • Flexible floor plan and established professional setting with existing infrastructure.
    • Walkable to restaurants, shops, ferry terminals, and public transportation.
    Updated: Mar 17
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    Renovated Hyannis Office Spaces
    $1,000/Mo
    7,960 SF

    Renovated Hyannis Office Spaces

    460 Bearses Way, Hyannis, MA 02601

    Move-in ready office spaces in prime Hyannis location.

    • Prime Hyannis location with excellent access to major routes, businesses, and local amenities.
    • Turnkey, move‑in‑ready professional office spaces, recently renovated.
    • All‑inclusive utilities included in monthly rent.
    • Each unit has its own brand‑new mini‑split system for efficient heating and air conditioning.
    • Three units available, each approximately 270 sq ft, suitable for various professional uses.
    Updated: Apr 13
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    Centerville Commercial Space For Rent
    $1,300/Mo
    1,736 SF

    Centerville Commercial Space For Rent

    Commercial space in bustling Centerville Village near beaches.

    628 Craigville Beach Road, Centerville, MA 02632
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    Free Standing Building in Cotuit
    $2,500/Mo
    1,615 SF

    Free Standing Building in Cotuit

    Two-level commercial building for lease in Cotuit center.

    5 Main Street, Cotuit, MA 02635
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    Prime Retail Space on Main
    $1,800/Mo
    532 SF

    Prime Retail Space on Main

    Highly visible commercial condo in the heart of Hyannis.

    569 Main Street, Hyannis, MA 02601
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    Hyannis Restaurant Space with Kitchen
    $72,000 SF/Yr
    4,259 SF

    Hyannis Restaurant Space with Kitchen

    Restaurant space with commercial kitchen in high-traffic Hyannis location.

    615 Main Street, Hyannis, MA 02601
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    Prime Hyannis Commercial Space
    $39,100 SF/Yr
    2,228 SF

    Prime Hyannis Commercial Space

    Historic Main Street location ideal for retail, restaurant, or office.

    615 Main Street, Hyannis, MA 02601
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    Prime Office Space in Hyannis
    $84 SF/Yr
    4,004 SF

    Prime Office Space in Hyannis

    Professional office space for lease in downtown Hyannis.

    33 Bassett Lane, Barnstable, MA 02630
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    Hyannis Commercial Space Available
    $23 SF/Yr
    7,792 SF

    Hyannis Commercial Space Available

    Versatile commercial space in Hyannis with showroom and office potential.

    1047 Falmouth Road, Hyannis, MA 02601
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    Renovated Office Space Available
    $650/Mo
    6,568 SF

    Renovated Office Space Available

    Renovated office space with utilities included in West Barnstable.

    1025 Main Street, West Barnstable, MA 02668
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    Retail Unit in Hyannis Plaza
    $2,438/Mo
    1,500 SF

    Retail Unit in Hyannis Plaza

    Retail space for lease in Hyannis, Massachusetts.

    489 Bearse's Way, Hyannis, MA 02601
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    New Retail/Restaurant Space Available
    $33 SF/Yr
    4,533 SF

    New Retail/Restaurant Space Available

    New construction retail/restaurant space at Staples Plaza in Hyannis.

    378B Barnstable Road, Barnstable, MA 02630
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    Versatile Commercial Space Available
    $22 SF/Yr
    3,000 SF

    Versatile Commercial Space Available

    Multiple units available with office, showroom, and gym potential.

    Hyannis, MA 2601
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    Prime Retail Space on Main
    $2,250/Mo
    1,300 SF

    Prime Retail Space on Main

    Move-in ready retail space in Hyannis' commercial corridor.

    376 Main St, Barnstable, MA 2601
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    Prime Retail Space Available
    $22 SF/Yr
    2,800 SF

    Prime Retail Space Available

    2,800 SF retail space for lease in Centerville, MA.

    Barnstable, MA
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    Restaurant Space in Hyannis BID
    $72,000 SF/Yr
    4,200 SF

    Restaurant Space in Hyannis BID

    Restaurant space with full commercial kitchen in high-traffic area.

    615 Main Street #14, Hyannis, MA 2601
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    Versatile Commercial Space Available
    $22 SF/Yr
    3,000 SF

    Versatile Commercial Space Available

    Adaptable commercial unit with showroom and office space.

    1047 Falmouth Road #Unit 6, Hyannis, MA 2601
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    Main Street Retail/Office Opportunity
    $39,100 SF/Yr
    2,200 SF

    Main Street Retail/Office Opportunity

    Prime location for retail, restaurant, or office in Hyannis.

    615 Main Street #13, Hyannis, MA 2601
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    Retail Space in Hyannis
    Contact for pricing
    25,208 SF

    Retail Space in Hyannis

    Retail property for lease in high-traffic Cape Cod location.

    Barnstable, MA 02634
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    Retail Space Available For Lease
    Contact for pricing
    17,645 SF

    Retail Space Available For Lease

    17,645 SF retail space with strong co-tenancy.

    665 Iyannough Rd, Barnstable, MA
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    Retail Space Available For Lease
    Contact for pricing

    Retail Space Available For Lease

    Retail space available for lease in Hyannis, Massachusetts.

    655 Iyannough Rd, Hyannis, MA, Barnstable, MA 2601
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    Retail Space on Route 28
    Contact for pricing
    1,300 SF

    Retail Space on Route 28

    1,300 sq. ft. retail space available for rent.

    2948 Falmouth Rd, Barnstable, MA 2655
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    Based on your search, we've compiled 102 Potential Opportunities for your consideration. Besides 22 Active listings in Hyannis, MA, we suggest exploring alternatives. Similar 80 Properties for Sales.

    Similar Spaces for Sale in Hyannis, MA

    Consider Similar Space for Sale. We found 80 Spaces matching your search parameters.

    West Barnstable Commercial-Residential Opportunity
    $1,450,000
    6,684 SF

    West Barnstable Commercial-Residential Opportunity

    Multi-use property with business and residential potential on Route 6A.

    1049 Main Street, West Barnstable, MA 02668
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    Barnstable Harbor Waterfront Legacy Property
    $1,995,000
    2,968 SF

    Barnstable Harbor Waterfront Legacy Property

    Iconic waterfront property with pier and marine workshops.

    164 Beale Way, Barnstable, MA 02630
    View details

    Hyannis, MA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Hyannis, MA with 22 listings featured on our commercial real estate exchange. The current inventory includes 61,395 square feet of properties with an estimated lease value of $222,533.

    Estimated lease rates for Commercial real estate in Hyannis, MA begin at $1.19 SF/Yr, with an average of $12,362 /Mo and extend to $72,000.
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    Most Searched ZIP Codes in Hyannis, MA

    • 02601
    • 02630
    • 02632
    • 02634
    • 02635
    • 02668
    • 02655

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