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    Spartanburg County, SC Mixed-use Properties for Lease

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    Historic Mill Office Space Available
    $28 SF/Yr

    Historic Mill Office Space Available

    1802 Drayton Rd, Spartanburg, SC 29307

    Creative office space in a vibrant mixed-use community.

    • Located in Drayton Mills Marketplace, a successful adaptive‑reuse mixed‑use community.
    • ±3,934 SF office suite with restored historic mill character including exposed brick, high ceilings, and large windows.
    • Walkable access to restaurants, coffee shops, retail, fitness studio, and salons.
    • Connected to Drayton Mills’ trail network for walking, biking, and tenant events.
    • Flexible space suitable for office, creative studio, co‑working, or boutique professional services.
    View details
    Spartanburg Flexible Space For Rent
    Contact for pricing
    19,000 SF

    Spartanburg Flexible Space For Rent

    1201 Union St, Spartanburg, SC 29302

    Flexible space suitable for retail or mixed-use purposes.

    • ±34,000‑SF Flexible Space suitable for retail/mixed‑use.
    • Direct access and street frontage on Union St.
    • Located minutes from Downtown Spartanburg.
    • Abundant parking.
    • Adjacent concrete slab ideal for development.
    Updated: Oct 21, 2025
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    Historic Spartanburg Mixed-Use Retail Space
    Contact for pricing

    Historic Spartanburg Mixed-Use Retail Space

    Retail space available in historic mixed-use building in downtown Spartanburg.

    174 E Main St, Spartanburg, SC 29306
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    Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 3 Active listings in Spartanburg County, SC, we suggest exploring alternatives. Similar 18 Properties for Sales.

    Explore Similar Spaces for Sale in Spartanburg County, SC

    Consider Similar Space for Sale. We found 18 Spaces in Nearby Locations matching your search parameters.

    Versatile Commercial Property in Spartanburg
    $799,000
    2,900 SF

    Versatile Commercial Property in Spartanburg

    Functional space with expansion potential near Downtown Spartanburg.

    449 W Centennial St, Spartanburg, SC 29303
    View details
    Commercial Property Near Interstate 26
    $1,350,000
    7,500 SF

    Commercial Property Near Interstate 26

    2.75 acre commercial property with 7,500 SF building.

    1385 Meadow Farm Rd, Inman, SC 29349
    View details
    Restaurant/Convenience Store with Living Area
    $175,000
    1,500 SF

    Restaurant/Convenience Store with Living Area

    Commercial restaurant/convenience store with living area in Cross Anchor, SC.

    701 Union Hwy, Cross Anchor, SC 29335
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    Spartanburg Mixed-Use Investment Opportunity
    $325,000
    1.53 Acres

    Spartanburg Mixed-Use Investment Opportunity

    Mixed-use property with income potential near Interstates 85 and 26.

    511 Broadcast Dr, Spartanburg, SC 29303
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    Versatile Mixed-Use Spartanburg Property
    $110,000
    3,388 SF

    Versatile Mixed-Use Spartanburg Property

    3388 sq ft mixed-use property with conversion potential in Spartanburg.

    100 Clary Dr, Spartanburg, SC 29303
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    Versatile Mixed-Use Property in Inman
    $285,000
    2,964 SF

    Versatile Mixed-Use Property in Inman

    Commercial property with office space and a residential apartment.

    1 Anderson Street Ext, Inman, SC 29349
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    Spartanburg Multi-Use Investment Opportunity
    $200,000
    0.71 Acres

    Spartanburg Multi-Use Investment Opportunity

    Investment property with tenants in place near Spartanburg city limits.

    170 S Blackstock Rd, Spartanburg, SC 29301
    View details
    Cowpens Mixed-Use Building For Sale
    $195,000
    1,700 SF

    Cowpens Mixed-Use Building For Sale

    Mixed-use building with recent upgrades in Cowpens, South Carolina.

    5286 S Main St, Cowpens, SC 29330
    View details
    Mixed-Use Property in Spartanburg
    $200,000
    1,300 SF

    Mixed-Use Property in Spartanburg

    Investment opportunity with tenants in place near Spartanburg City Limits.

    170 S Blackstock Rd, Spartanburg, SC 29301
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    Industrial Warehouse and Office Property
    Contact for pricing

    Industrial Warehouse and Office Property

    4 buildings on 5.29 acres in Spartanburg County.

    4139 S Church Street Ext, Roebuck, SC 29376
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    Roebuck Mixed-Use Investment Opportunity
    $285,000
    2.21 Acres

    Roebuck Mixed-Use Investment Opportunity

    2.21 Acres, House, Development Potential

    480 Wingo Rd, Roebuck, SC 29376
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    Spartanburg Retail Land - $850K+
    $850,000
    1.00 Acre

    Spartanburg Retail Land - $850K+

    Prime East Side Spartanburg land, QSR/Restaurant ready.

    2300 Main St, Spartanburg, SC 29307
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    Prime Spartanburg Mixed-Use Property
    $1,280,000
    0.66 Acres

    Prime Spartanburg Mixed-Use Property

    Versatile building, ideal location, high potential.

    230 Dean St, Spartanburg, SC 29302
    View details
    Versatile Commercial Building Near Hospital
    Contact for pricing
    11,925 SF

    Versatile Commercial Building Near Hospital

    Adaptable commercial building suitable for medical, retail, or storage use.

    200 Dillon Cir, Spartanburg, SC 29307
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    Highway Frontage Automotive/Industrial Opportunity
    Contact for pricing
    4,300 SF

    Highway Frontage Automotive/Industrial Opportunity

    4,300 SF property on 3.82 acres near downtown Spartanburg.

    2940 S Pine St, Spartanburg, SC 29302
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    Historic Mixed-Use Property For Sale
    Contact for pricing
    4,688 SF

    Historic Mixed-Use Property For Sale

    4,688 SF mixed-use property in Converse Heights neighborhood.

    571 E Main St, Spartanburg, SC 29302
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    Landrum Commercial Building with Warehouse
    Contact for pricing
    4,000 SF

    Landrum Commercial Building with Warehouse

    4,000 sq ft mixed-use building in Landrum, South Carolina.

    146 S 562, Landrum, SC 29356
    View details
    Prime Land on E. Main
    Contact for pricing
    10,000 SF

    Prime Land on E. Main

    7.76 acres on a busy commercial corridor, redevelopment opportunity.

    2700 E Main St, Spartanburg, SC 29307
    View details

    Spartanburg County, SC Mixed-use properties Leasing Opportunities Market Analysis

    Explore Mixed-use properties leasing options in Spartanburg County, SC with 3 listings featured on our commercial real estate exchange. The current inventory includes 827,640,000 square feet of properties with an estimated lease value of $28 SF/Yr.

    Estimated lease rates for Mixed-use properties in Spartanburg County, SC begin at $28 SF/Yr, with an average of $28 SF/Yr and extend to $28 SF/Yr.
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    Mixed-use properties by market

    Browse Mixed-use properties for Lease Near Spartanburg, SC

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