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Grayson County, TX Medical Offices for Lease

20 results
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Medical Office Space Available
$19 SF/Yr
40,075 SF

Medical Office Space Available

3305 N Calais Dr, Sherman, TX 75090

Highly visible medical office space in a high-traffic area.

  • Highly visible medical office space in a high‑traffic, well‑established area
  • One month free rent to assist with move‑in
  • Ideal for healthcare providers looking to grow or relocate
  • Functional and accessible layout
  • Central heating and central air conditioning
Updated: Jan 30
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Sherman Office Suites For Rent
$19 SF/Yr
62,291 SF

Sherman Office Suites For Rent

1800 Teague Dr, Sherman, TX 75090

Professional office suites in Sherman's premier five-story office building.

  • Prime location near Hwy 75, retail, and dining.
  • Flexible floorplans with multiple suite configurations available.
  • Anytime secure access.
  • Abundant natural light fills the space.
  • On‑site conference room available for meetings.
Updated: Dec 6, 2025
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Van Alstyne Office Building Available
$3,600 / Mo
207,607 SF

Van Alstyne Office Building Available

Office building in a high-traffic area of fast-growing Van Alstyne.

12302 Fm 121, Van Alstyne, TX 75495
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Office Space in Central Denison
$2,100 / Mo
24,002 SF

Office Space in Central Denison

Office space with kitchen facilities, suitable for medical or professional tenant.

1725 S Austin Ave, Denison, TX 75020
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Sherman Office Space For Lease
$2,000 / Mo
1,500 SF

Sherman Office Space For Lease

Updated office/medical space with Highway 75 visibility in Sherman, TX.

1313 N Travis St, Sherman, TX 75090
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Updated Office Space For Lease
$2,600 / Mo
50,530 SF

Updated Office Space For Lease

Centrally located office space with Highway 75 visibility in Sherman.

1303 N Travis St, Sherman, TX 75092
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Medical Office in Sherman, TX
$20 SF/Yr
22,651 SF

Medical Office in Sherman, TX

Turnkey medical office space in a growing Sherman corridor.

1700 Gallagher Dr, Sherman, TX 75090
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Sherman Retail/Medical Office Space
$12 SF/Yr
18,885 SF

Sherman Retail/Medical Office Space

Retail or medical office space available in Sherman, Texas.

2121 N Fm 1417, Sherman, TX 75092
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Denison Office with Natural Light
$3,500 / Mo
125,017 SF

Denison Office with Natural Light

Versatile office space with abundant natural light and unique features.

1331 Memorial Dr, Denison, TX 75020
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Denison Office Space For Rent
$1,800 / Mo
6,490 SF

Denison Office Space For Rent

Move-in ready office space in a high-traffic Denison location.

1110 S Armstrong Ave, Denison, TX 75020
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Medical Office Space Near Texoma
$17,150 / Mo
7,350 SF

Medical Office Space Near Texoma

Prime medical office space available for lease near Texoma Medical Center.

2416 Swamy Dr, Sherman, TX 75090
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Sherman Medical Office Space
$18 SF/Yr
112,129 SF

Sherman Medical Office Space

Modern Medical Office Suites Available

300 Highland Ave, Sherman, TX 75090
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Gateway Central Medical Office Space
$15 SF/Yr
140,000 SF

Gateway Central Medical Office Space

Denison, TX: Class A medical office suites available

4616 Us Highway 75, Denison, TX 75020
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Gunter Retail Center: Prime Space
Contact for pricing
43,537 SF

Gunter Retail Center: Prime Space

New retail building, medical, restaurant space available.

615 Preston Rd, Gunter, TX 75058
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Whitesboro Retail/Office Space
Contact for pricing
3,000 SF

Whitesboro Retail/Office Space

New construction, flexible suites, prime location.

0 Union St, Whitesboro, TX 76273
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Medical Office Space For Lease
$22 SF/Yr
1,477 SF

Medical Office Space For Lease

Class-A medical office space on Texoma Medical Center campus.

3025 Fm 691, Denison, TX 75020
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Highway 75 Office Property
$19 SF/Yr

Highway 75 Office Property

Versatile office space with highway visibility and accessibility.

101 Us Highway 75, Denison, TX 75020
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Denison Office Space For Lease
$19 SF/Yr
6,289 SF

Denison Office Space For Lease

Office suite for lease with high visibility and traffic.

101 Hwy N, Denison, TX
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Medical Office Space Available
$12 SF/Yr

Medical Office Space Available

Finished medical office space with signage available in Sherman, TX.

2121 Q, Sherman, TX 75092
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Medical Office Space Available
Contact for pricing
3,716 SF

Medical Office Space Available

Retail/medical office building with great exposure off Taylor Street.

715 E Taylor St, Sherman, TX 75090
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Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 20 Active listings in Grayson County, TX, we suggest exploring alternatives. Similar 6 Properties for Sales.

Explore Similar Spaces for Sale in Grayson County, TX

Consider Similar Space for Sale. We found 6 Spaces in Nearby Locations matching your search parameters.

Sherman, TX - Veterinary Office
$375,000
0.34 Acres

Sherman, TX - Veterinary Office

Veterinary office in downtown Sherman with multiple rooms and outdoor storage.

825 N Crockett St, Sherman, TX 75090
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Medical Office Building For Sale
$1,350,000
5,250 SF

Medical Office Building For Sale

5,250 SF medical office building in high-visibility Sherman location.

815 Pecan Grove Rd E, Sherman, TX 75090
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Medical Office Condo Near Hospital
$150,000
1.60 Acres

Medical Office Condo Near Hospital

Well-equipped medical office condo adjacent to Wilson N. Jones Medical Center.

425 N Highland Ave, Sherman, TX 75092
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Sherman Medical Office Building
$1,300,000
0.52 Acres

Sherman Medical Office Building

Turnkey medical office in a high-growth Sherman corridor.

1700 Gallagher Dr, Sherman, TX 75090
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Grayson County, TX Medical offices Leasing Opportunities Market Analysis

Explore Medical offices leasing options in Grayson County, TX with 26 listings featured on our commercial real estate exchange. The current inventory includes 21,504,212,983 square feet of properties with an estimated lease value of $193 SF/Yr.

Estimated lease rates for Medical offices in Grayson County, TX begin at $0.62 SF/Yr, with an average of $14 SF/Yr and extend to $28 SF/Yr.
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