Medical Space

Hidalgo County, TX Medical Office Space for Lease

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91 properties
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Medical Office with Exam Rooms
Updated: Oct 26
Medical Office with Exam Rooms

110 E Savannah Avenue, Mcallen, TX 78503

$2,700/Mo
1,998 sqft 0.11 AC lot
1,998 square feet of medical office space
Five exam rooms, lobby, and front‑desk reception
Medical records area, employee lounge, and physician’s office
Wide hallway designed to accommodate wheelchair and stretcher passage
Accessible approach ramp and special‑needs parking
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Medical Office Space
Updated: Oct 30
Medical Office Space

1200 S 10th Avenue, Edinburg, TX 78539

$1,600/Mo
1,300 sqft 0.49 AC lot
1,300 square feet of medical office space
Adjacent to an established medical practice
F1 zoning
Building constructed in 1982
Located at 1200 S 10th Avenue, Edinburg, TX 78539
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Finished Office Suite
Finished Office Suite

1112 E Griffin Parkway, Mission, TX 78572

$2,400/Mo
8–14 people  2,200 sqft  Built 2004  1.08 acres
Road access

Suite 1112-C offers a completed interior and access from Bryan Road and Griffin Parkway.

10 parking spaces  Courtyard  Balcony
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Medical Office Suite with Dental Buildout
Medical Office Suite with Dental Buildout

1601 W Trenton Road #J, Edinburg, TX 78539

$5,900/Mo
2,786 sqft  Built 2017

Existing improvements configure the leased space for dental practice use.

20 parking spaces
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Four-Suite Office Property
Four-Suite Office Property

111 N 17th Street, Donna, TX 78537

$4,545/Mo
11–19 people  2,951 sqft  Built 2011  0.95 acres

Flexible office configuration with three suites currently available for lease in Donna.

50 parking spaces
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Office Unit with Conference Room
Office Unit with Conference Room

1009 Utah Avenue, Weslaco, TX 78596

$1,500/Mo
4–8 people  1,200 sqft  Built 2003  0.08 acres
5 private offices  1 meeting room

Five-office layout with reception, restrooms, and covered parking supports a range of professional office operations.

Reception area
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Medical Office Suite with Patient Rooms
Medical Office Suite with Patient Rooms

2134 E Griffin Parkway, Mission, TX 78572

$2,000/Mo
2,970 sqft  Built 2003  0.22 acres

Configured with clinical rooms, private offices, reception, storage, and a break area.

11 parking spaces
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Medical Office Suites
Medical Office Suites

427 E Duranta Avenue #101, Alamo, TX 78516

$7,221/Mo
4,814 sqft  Built 2007
Highway access

Three suite options offer flexible floor plans for medical and professional office operations.

402 parking spaces
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Two-Suite Office Space
Two-Suite Office Space

412 E 18th Street, Weslaco, TX 78596

$1,300/Mo
3–6 people  900 sqft  Built 1990  1.39 acres
2 private offices

Professional layout includes a reception area, private offices, one-and-a-half bathrooms, and on-site parking.

8 parking spaces
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Multi-Suite Office Property
Multi-Suite Office Property

3304 W Alberta Road, Edinburg, TX 78539

$10,500/Mo
36–60 people  9,000 sqft  Built 1999  0.21 acres

ADA-compliant facilities and full utilities support accessible office operations.

200 parking spaces  ADA-compliant facilities
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Mixed-Use Commercial Suite
Mixed-Use Commercial Suite

1352 E 1st Street #B-3, Mission, TX 78572

$3,366/Mo
3,366 sqft  Built 2006
Highway access

The 2006-built space occupies a multi-use plaza near Expressway 83.

8 parking spaces
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Four-Suite Office Property
Four-Suite Office Property

111 N 17th Street, Donna, TX 78537

$2,603/Mo
6–11 people  1,690 sqft  Built 2011  0.95 acres

Professional office configuration with an accessible ramp approach and special-needs parking feature.

50 parking spaces
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Medical Office Suite
Medical Office Suite

2604 E Richardson Road, Edinburg, TX 78542

Triple net (NNN)
$4,225/Mo
Multi-tenant  2,520 sqft  Built 2010  1.63 acres

Office space within an established medical and professional plaza serving medical, office, and specialty users.

40 parking spaces
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Second-Generation Office Suite with Pylon
Second-Generation Office Suite with Pylon

1002 W Sam Houston Boulevard, Pharr, TX 78577

$3,772/Mo
11–19 people  2,961 sqft  Built 1997
Highway access

Move-in ready second-generation office suite with build-out available within Pharr Medical Complex, featuring pylon signage opportunity.

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Multi-Tenant Shopping Center
Multi-Tenant Shopping Center

2000 S Mccoll Road, Mcallen, TX 78503

$2,462/Mo
Multi-tenant  14,072 sqft  Built 2000
Pizza Hut, Subway co-tenants  Highway access

Multi-tenant plaza near hospitals, major retailers, and established commercial destinations.

123 parking spaces
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End-Cap Medical Office Space
End-Cap Medical Office Space

1913 S 1st Street, Mcallen, TX 78503

Triple net (NNN)
$4,111/Mo
1,986 sqft  Built 1986  0.18 acres

Updated end-cap facility with exam rooms, offices, a lobby, conference area, kitchenette, and off-street parking.

14 parking spaces
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Medical Office Suites with Drive-Through
Medical Office Suites with Drive-Through

1002 Ste #7 W Sam Houston Boulevard, Pharr, TX 78577

$3,772/Mo
24,089 sqft  Built 1997
Highway access

Three available suites include a former pharmacy, a dental office, and a former rehabilitation clinic.

123 parking spaces
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Four-Suite Office Units
Four-Suite Office Units

111 N 17th Street, Donna, TX 78537

$2,660/Mo
6–11 people  1,727 sqft  Built 2011  0.95 acres

Flexible four-suite office configuration with ramp access and designated special-needs parking.

50 parking spaces
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Medical Office Suite with Indoor Pool
Medical Office Suite with Indoor Pool

5331 Mccoll Road, Edinburg, TX 78539

$7,980/Mo
6,300 sqft  Built 1997

Medical suite with 17 exam/office rooms and central reception designed for organized patient check-in and flow.

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Updated Office Unit
Updated Office Unit

407 N 10th Street, Mcallen, TX 78501

$2,200/Mo
7–11 people  1,778 sqft  Built 1993
Highway access

Move-in-ready professional workspace with refreshed interiors and dedicated client and staff parking.

7 parking spaces
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2-Suite Office Property
2-Suite Office Property

1523 S 10th Ave, Edinburg, TX 78539

$3,000/Mo
9–15 people  2,313 sqft  Built 2019
General Commercial

General Commercial-zoned office space along W. Freddy Gonzalez Drive, near medical, dental, retail, restaurant, and other commercial services.

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Build-to-Suit Retail Space
Build-to-Suit Retail Space

2345 Military Highway, Hidalgo, TX 78503

$6,250/Mo
2,400 sqft  Built 1992

C1-zoned commercial space offers adaptable planning for retail, medical, office, or service-based operations.

24 parking spaces
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Outpatient Rehabilitation Center with Treatment Rooms
Outpatient Rehabilitation Center with Treatment Rooms

1400 E Ridge Rd Unit 2, Mcallen, TX 78504

$6,000/Mo
3,100 sqft  Built 2003

Configured with private treatment rooms, reception space, restrooms, and parking for healthcare operations.

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Medical Office Space with Ramp
Medical Office Space with Ramp

712 S Nebraska Avenue, San Juan, TX 78589

$3,995/Mo
5,970 sqft  Built 1991  0.3 acres

F1-zoned medical office space with an accessible approach and ramp at the building entrance.

20 parking spaces
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Hidalgo County, TX Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Hidalgo County, TX with 91 listings featured on our commercial real estate exchange. The current inventory includes 362,955 square feet of properties with an estimated lease value of $1,201.

Estimated lease rates for Medical Office Space in Hidalgo County, TX begin at $1.03 SF/Yr, with an average of $18.77 SF/Yr and extend to $36 SF/Yr.
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