Texas
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent / SF / Yr
    $
    $
    Size
    Property Size / SF

    Grayson County, TX Medical Office Space for Lease

    Notify Me
    List
    Map
    25 results
    Versatile Office Space in Denison
    $3,000/Mo

    Versatile Office Space in Denison

    1331 Memorial Drive, Denison, TX 75020

    12,000+ sq ft commercial property near Hwy 75.

    • High‑traffic visibility and proximity to Hwy 75 and downtown Denison offer excellent business exposure.
    • Expansive 12,000+ sq ft commercial property provides significant space and versatility.
    • Abundant natural light and views of a wooded landscape and creek create an inspiring work environment.
    • Flexible layout with open and private spaces accommodates diverse business needs.
    • Secure, solid concrete former imaging room with steel doors suitable for a radiology suite, server room, or high‑value storage.
    Updated: Mar 21
    View details
    Denison Office Space For Rent
    $1,500/Mo

    Denison Office Space For Rent

    1110 S Armstrong Avenue, Denison, TX 75020

    Move-in ready office space with reception, restrooms, break room.

    • Reduced Rent and First Month FREE
    • Excellent location on major thoroughfare in Denison
    • Move‑in ready condition
    • Large suite of offices with reception area, two restrooms, and break room
    • Parking in front and back
    Updated: Apr 18
    View details
    Versatile Office Space Available
    $4,000/Mo

    Versatile Office Space Available

    Approximately 1500 sq. ft. office space for sublease.

    13980 Fm 121, Van Alstyne, TX 75495
    View details
    Updated Office Space For Lease
    $2,600/Mo

    Updated Office Space For Lease

    Centrally located office space with Highway 75 visibility in Sherman.

    1303 N Travis Street, Sherman, TX 75092
    View details
    Office Space in Central Denison
    $2,100/Mo

    Office Space in Central Denison

    Office space with kitchen facilities, suitable for medical or professional tenant.

    1725 S Austin Avenue, Denison, TX 75020
    View details
    Medical Office Space Near Texoma
    $17,150/Mo
    7,350 SF

    Medical Office Space Near Texoma

    Prime medical office space available for lease near Texoma Medical Center.

    2416 Swamy Drive, Sherman, TX 75090
    View details
    Medical Office in Sherman, TX
    $20 SF/Yr

    Medical Office in Sherman, TX

    Turnkey medical office space in a growing Sherman corridor.

    1700 Gallagher Drive, Sherman, TX 75090
    View details
    Medical Office Space Available
    $19 SF/Yr

    Medical Office Space Available

    Highly visible medical office space in a high-traffic area.

    3305 N Calais Drive, Sherman, TX 75090
    View details
    Sherman Office Suites For Rent
    $19 SF/Yr

    Sherman Office Suites For Rent

    Professional office suites in Sherman's premier five-story office building.

    1800 Teague Drive, Sherman, TX 75090
    View details
    Sherman Retail/Medical Office Space
    $12 SF/Yr
    18,885 SF

    Sherman Retail/Medical Office Space

    Retail or medical office space available in Sherman, Texas.

    2121 N Fm 1417, Sherman, TX 75092
    View details
    Denison Office Space For Lease
    $19 SF/Yr
    6,289 SF

    Denison Office Space For Lease

    Office suite for lease with high visibility and traffic.

    101 N Hwy 75, Denison, TX 75020
    View details
    Denison Commercial Property for Rent
    $3,000/Mo
    12,181 SF

    Denison Commercial Property for Rent

    Spacious 12,000+ sq ft commercial property near Hwy 75.

    1331 Memorial Drive, Denison, TX 75020
    View details
    Medical Office Space Available
    $12 SF/Yr
    4,300 SF

    Medical Office Space Available

    Finished medical office space available for lease near Walmart.

    2121 N Fm 1417 #Q, Sherman, TX 75092
    View details
    Sherman Medical Office For Rent
    $20 SF/Yr
    4,397 SF

    Sherman Medical Office For Rent

    Turnkey medical office space in a growing Sherman corridor.

    1700 Gallagher Drive, Sherman, TX 75090
    View details
    Medical Office Space For Lease
    $17,150/Mo
    7,350 SF

    Medical Office Space For Lease

    Prime medical office space across from Texoma Medical Center.

    2416 Swamy Drive, Sherman, TX 75090
    View details
    Highway 75 Office Space
    $19 SF/Yr
    6,289 SF

    Highway 75 Office Space

    Adaptable office space with high visibility on Highway 75.

    101 Us Hwy 75, Denison, TX 75020
    View details
    Versatile Office Space Available
    $4,000/Mo
    1,500 SF

    Versatile Office Space Available

    1500 sq ft office space suitable for multiple uses.

    13980 Fm 121, Van Alstyne, TX 75495
    View details
    Denison Office Space For Rent
    $1,500/Mo
    2,135 SF

    Denison Office Space For Rent

    Move-in ready office space in a high-traffic Denison location.

    1110 S Armstrong Avenue, Denison, TX 75020
    View details
    Sherman Office Suite For Rent
    $14 SF/Yr
    1,245 SF

    Sherman Office Suite For Rent

    Office suite in thriving plaza with highway access.

    200 E Evergreen Street, Sherman, TX 75090
    View details
    West Sherman Office Suite
    $19 SF/Yr
    921 SF

    West Sherman Office Suite

    Garden-style office suite in West Sherman, built in 2019.

    2620 N Travis, Sherman, TX 75092
    View details
    Medical Office Space For Lease
    $19 SF/Yr
    2,915 SF

    Medical Office Space For Lease

    Highly visible medical office space in a high-traffic area.

    3305 N Calais Drive, Sherman, TX 75090
    View details
    Central Area Office Space Available
    $2,100/Mo
    2,400 SF

    Central Area Office Space Available

    Office space for lease in central location near Eisenhower Parkway.

    1725 S Austin Avenue, Denison, TX 75020
    View details
    Medical Office Space For Lease
    $22 SF/Yr
    1,477 SF

    Medical Office Space For Lease

    Class-A medical office space on Texoma Medical Center campus.

    3025 FM691, Denison, TX
    View details
    Denison Commercial Building For Lease
    Contact for pricing
    3,656 SF

    Denison Commercial Building For Lease

    3,656 SF renovated building on 2.74 acres for lease.

    1020 US HIGHWAY 69, Denison, TX 75020
    View details

    Grayson County, TX Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Grayson County, TX with 25 listings featured on our commercial real estate exchange. The current inventory includes 79,634 square feet of properties with an estimated lease value of $266 SF/Yr.

    Estimated lease rates for Medical Office Space in Grayson County, TX begin at $2 SF/Yr, with an average of $17 SF/Yr and extend to $32 SF/Yr.
    List
    Map