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    Grayson County, TX Medical Office Space for Lease

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    14 properties
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    Medical Office Space with Blank Shell
    Updated: Jun 2
    Medical Office Space with Blank Shell

    2416 Swamy Drive, Sherman, TX 75090

    $17,150/Mo
    7,350 sqft
    Blank‑shell medical office space suitable for a custom interior build‑out
    Can be configured as 4 spaces or occupied by one tenant
    Located across from Texoma Medical Center
    Positioned at Highway 75 and FM 691
    2025 construction with stucco exterior and flat synthetic roof
    View details
    Office Suite with Reception Area
    Updated: Jul 11
    Office Suite with Reception Area

    1110 S Armstrong Avenue, Denison, TX 75020

    $1,500/Mo
    0.15 AC lot
    Reception area, two restrooms, and break room included
    Off‑street parking available in front and behind the property
    Sign post available for tenant identification
    Former medical‑office configuration
    0.149‑acre property at 1110 S Armstrong Avenue
    View details
    Medical Office Suite
    Medical Office Suite

    3305 N Calais Drive, Sherman, TX 75090

    $16 SF/Yr
    2,915 sqft  Built 1991  0.92 acres

    A dedicated medical office configuration includes central heating and air conditioning, with parking available in an on-site lot.

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    Medical Office Space with Kitchen
    Medical Office Space with Kitchen

    1725 S Austin Ave, Denison, TX 75020

    $1,700/Mo
    6,800 sqft  Built 1980
    Highway access

    Office space includes a sink, refrigerator, trash compactor, and dedicated kitchen facilities.

    Kitchen facilities  Sink  Refridgerater  Trash compactor
    View details
    Office Suite with Reception Area
    Office Suite with Reception Area

    1110 S Armstrong Avenue, Denison, TX 75020

    $1,500/Mo
    8–14 people  2,135 sqft  Built 1950
    Road access

    The suite includes a break room, two restrooms and parking at both the front and rear.

    Reception area  Restrooms  Break room  Sign post
    View details
    Medical Office Suite
    Medical Office Suite

    3305 N Calais Dr, Sherman, TX 75090

    $16 SF/Yr
    8,375 sqft  Built 1991

    Professional medical office space suited to healthcare providers seeking a functional practice setting.

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    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    1700 Gallagher Dr, Sherman, TX 75090

    $20 SF/Yr
    4,397 sqft  Built 2006  2-story
    Highway access  Road access

    Two-story medical office with clinical rooms, private offices, imaging space, patient reception areas, storage, and staff amenities.

    Drive through awning  X-Ray room  Nurses station  Lobby
    View details
    Medical Office Space for Lease
    Medical Office Space for Lease

    5012 S US-75, Denison, TX 75020

    $1,251/Mo
    120,000 sqft

    Medical office space available on US Highway 75 with addresses at 5012 S and 5125 US Highway 75 in Denison, TX.

    View details
    Office Units at Evergreen Office Plaza
    Office Units at Evergreen Office Plaza

    200 E Evergreen St, Sherman, TX 75090

    Triple net (NNN)
    $14 SF/Yr
    93–156 people  23,458 sqft  Built 2000
    Highway access

    Suite space within a six-building office complex serving medical and professional users.

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    Office Building with Secure Imaging Room
    Office Building with Secure Imaging Room

    1331 Memorial Drive, Denison, TX 75020

    $500/Mo
    Built 1992

    Expansive office building with framed interiors, modern lighting, finished bathrooms, and a former imaging room with steel doors.

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    Shell Office Suite
    Shell Office Suite

    1615 North Highway 75, Sherman, TX 75090

    Contact for pricing
    10–17 people  2,650 sqft  Built 2015
    Highway access

    Suite 100 offers US-75 frontage within a modern commercial building suitable for professional or medical use.

    View details
    Medical Office Space For Lease
    Medical Office Space For Lease

    3025 FM691, Denison, TX

    Triple net (NNN)
    Contact for pricing
    1,477 sqft  5.76 acres

    Class-A medical office space on Texoma Medical Center campus.

    View details
    Mixed-Use Retail Development
    Mixed-Use Retail Development

    3200 US-75, Sherman, TX 75090

    Contact for pricing
    1.21 acres
    Highway access  Road access

    Mixed-use retail and commercial development with newly opened medical offices and existing fast food along high-visibility highways.

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    Medical Office Space Available
    Medical Office Space Available

    715 E Taylor St, Sherman, TX

    Contact for pricing
    3,716 sqft  0.68 acres

    Retail/medical office building with great exposure off Taylor Street.

    View details
    14 active listings match your search: Medical Office for lease in Grayson County, TX. Based on your search, we've also compiled 19 Potential Opportunities for your consideration: 19 properties for sale.

    Similar Spaces for Sale in Grayson County, TX

    Consider Similar Space for Sale. We found 19 Spaces matching your search parameters.

    Medical Office Building with Exam Rooms
    Medical Office Building with Exam Rooms

    3405 N Loy Lake Road, Sherman, TX 75090

    $995,000
    4,434 sqft 0.70 AC lot

    Flexible office layout with reception, private rooms, four bathrooms, and established commercial improvements.

    View details
    Medical Office Building with Exam Rooms
    Medical Office Building with Exam Rooms

    815 Pecan Grove Road E E, Sherman, TX 75090

    $1,350,000
    5,250 sqft

    Purpose-built medical facility with exam rooms, procedure rooms, private offices, and patient reception areas.

    View details
    Renovated Medical Office Building
    Renovated Medical Office Building

    300 N Bryant Ave, Sherman, TX 75090

    $675,000
    3,600 sqft

    Configured with exam rooms, multiple bathrooms, reception, and an upstairs open area.

    View details
    Office Building with Imaging Room
    Office Building with Imaging Room

    1331 Memorial Drive, Denison, TX 75020

    $668,000
    12,000 sqft

    Expansive office building with finished bathrooms, abundant natural light, and a former concrete imaging room with steel doors.

    View details
    Standalone Office Building
    Standalone Office Building

    1220 Reba Macentire Lane, Denison, TX 75020

    $957,000
    8,050 sqft 1.00 AC lot

    Versatile professional property with extensive storage, on-site parking, and a functional layout for service-oriented operations.

    View details
    Medical Office Building with Exam Rooms
    Medical Office Building with Exam Rooms

    1700 Gallagher Dr, Sherman, TX 75090

    $1,200,000
    4,397 sqft

    Two-level medical facility with patient areas, private offices, imaging space, and on-site storage.

    View details
    Denison Commercial Property on Highway 69
    Denison Commercial Property on Highway 69

    1020 N Us Highway 69, Denison, TX 75020

    $549,000
    3,656 sqft 2.74 AC lot

    Renovated 3,656 SF building on 2.74 acres.

    View details
    Office Building with New Roof
    Office Building with New Roof

    809 Gallagher Drive, Sherman, TX 75090

    $2,895,000
    2.65 AC lot

    Fully leased office property with parking, updated mechanical systems, and public utilities.

    View details
    Medical Office Building
    Medical Office Building

    3405 N Loy Lake Road, Sherman, TX 75090

    $995,000
    0.70 AC lot

    Configured with reception, waiting, private offices, exam rooms, and multiple bathrooms.

    View details
    Renovated Medical Office Building
    Renovated Medical Office Building

    300 N Bryant Avenue, Sherman, TX 75090

    $675,000
    0.34 AC lot

    Updated medical office with exam rooms, patient-facing areas, central HVAC, and public utilities.

    View details

    Grayson County, TX Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Grayson County, TX with 14 listings featured on our commercial real estate exchange. The current inventory includes 180,358 square feet of properties with an estimated lease value of $105.43.

    Estimated lease rates for Medical Office Space in Grayson County, TX begin at $3 SF/Yr, with an average of $15.06 SF/Yr and extend to $28 SF/Yr.
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    Featured Grayson County Real Estate Agencies

    Realmo connects you with licensed Grayson County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Homes By Lainie Real Estate Group
    421 Hwy. 120 West Pottsboro, TX 75076
    Phone: (903) 624-0688
    www.homesbylainie.com/
    XC Realty
    344 Pecan Crossing Ct Gunter, TX 75058
    Phone: (972) 741-7850
    www.xcrealtygroup.com/
    Tracy Realty
    800 W Main Denison, TX
    Phone: (903) 786-3115
    www.tracyrealty.net
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