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    Grayson County, TX Medical Office Space for Lease

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    Houston, TX Dallas, TX Austin, TX
    28 listings
    Blank-Shell Medical Office Building
    $17,150/Mo
    7,350 SF
    Blank-Shell Medical Office Building

    2416 Swamy Drive, Sherman, TX 75090

    High-visibility medical office shell across from Texoma Medical Center, ideal for custom build-outs or multi-suite leasing.
    • 7350 SF medical office building across from Texoma Medical Center; can be leased as 4 spaces or one tenant.
    • Blank‑shell design for custom build‑out and layout; property is under construction with Year Built 2025.
    • High‑visibility intersection location on Highway 75 and FM 691, where Sherman and Denison meet.
    • $28 per SF lease rate noted in public remarks.
    • Construction materials include stucco; roof is synthetic and flat.
    Updated: May 19
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    Fully Finished Medical Office Suite
    $12 SF/Yr
    18,885 SF
    Fully Finished Medical Office Suite

    2121 N Fm 1417, Sherman, TX 75092

    Turnkey medical office suite on the building’s northeast side with signage available and nearby retail and medical uses.
    • Fully finished medical office suite located at the intersection of FM 1417 and W Lamberth Rd, facing Lamberth Rd.
    • Available signage; vape shop use is not allowed by the city.
    • Lease list price excludes NNN; NNN is approximately $9/SF plus electric.
    • Suite is in a building that can be divisible up to 4,468 SF.
    • Year built 1983 with central electric heating and central air; flat tile roof.
    Updated: Jun 8
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    Move-In Ready Office Suite
    $1,500/Mo
    Move-In Ready Office Suite

    Reception-ready office suite with parking in front and back on a major Denison thoroughfare.

    1110 S Armstrong Avenue, Denison, TX 75020

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    Flexible Medical Office and Studio Space
    $3,000/Mo
    Flexible Medical Office and Studio Space

    Versatile interior layout with a secure former imaging room supports office, counseling, creative, or medical-focused operations.

    1331 Memorial Drive, Denison, TX 75020

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    Medical or Office Sublease Opportunity
    $4,000/Mo
    Medical or Office Sublease Opportunity

    Flexible office space with multiple private offices and shared amenities, well-suited for medical, insurance, or professional services.

    13980 Fm 121, Van Alstyne, TX 75495

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    Purpose-Built Medical Office
    $20 SF/Yr
    Purpose-Built Medical Office

    Turnkey medical facility with exam rooms, X-ray space, and two dedicated check-in areas for efficient patient flow.

    1700 Gallagher Drive, Sherman, TX 75090

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    Updated Office Suite with Highway Visibility
    $17 SF/Yr
    Updated Office Suite with Highway Visibility

    Updated office or medical office suite with reception, restrooms, break area, and multiple offices for professional use.

    1303 N Travis Street, Sherman, TX 75092

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    Medical Office Suite with Kitchen
    $2,100/Mo
    Medical Office Suite with Kitchen

    Well-maintained suite with kitchen amenities, suitable for medical, dental, or professional tenants.

    1725 S Austin Avenue, Denison, TX 75020

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    Highly Visible Medical Office Suite
    $19 SF/Yr
    Highly Visible Medical Office Suite

    Well-located suite suited for growing healthcare practices, offering visibility and a move-in incentive.

    3305 N Calais Drive, Sherman, TX 75090

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    Office Suites in Five-Story Building
    $21 SF/Yr
    Office Suites in Five-Story Building

    Flexible office suite options with secure access, conference space, and ample parking in a professional office setting.

    1800 Teague Drive, Sherman, TX 75090

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    Professional Office Suites in Five-Story Building
    $19 SF/Yr
    Professional Office Suites in Five-Story Building

    Flexible office suites with secure access, on-site conference space, and ample parking near Hwy 75.

    1800 Teague Drive, Sherman, TX 75090

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    Professional Office Suites at One Grand Centre
    $19 SF/Yr
    Professional Office Suites at One Grand Centre

    Flexible office and medical-ready suites with secure access, on-site conference space, and ample parking.

    1800 Teague Drive, Sherman, TX 75090

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    Denison Office Space For Lease
    $19 SF/Yr
    6,289 SF
    Denison Office Space For Lease

    Office suite for lease with high visibility and traffic.

    101 N Hwy 75, Denison, TX 75020

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    Denison Commercial Property for Rent
    $3,000/Mo
    12,181 SF
    Denison Commercial Property for Rent

    Spacious 12,000+ sq ft commercial property near Hwy 75.

    1331 Memorial Drive, Denison, TX 75020

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    Medical Office Space Available
    $12 SF/Yr
    4,300 SF
    Medical Office Space Available

    Finished medical office space available for lease near Walmart.

    2121 N Fm 1417 #Q, Sherman, TX 75092

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    Sherman Medical Office For Rent
    $20 SF/Yr
    4,397 SF
    Sherman Medical Office For Rent

    Turnkey medical office space in a growing Sherman corridor.

    1700 Gallagher Drive, Sherman, TX 75090

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    Medical Office Space For Lease
    $17,150/Mo
    7,350 SF
    Medical Office Space For Lease

    Prime medical office space across from Texoma Medical Center.

    2416 Swamy Drive, Sherman, TX 75090

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    Medical Office Space For Lease
    $22 SF/Yr
    1,477 SF
    Medical Office Space For Lease

    Class-A medical office space on Texoma Medical Center campus.

    3025 FM691, Denison, TX

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    Highway 75 Office Space
    $19 SF/Yr
    6,289 SF
    Highway 75 Office Space

    Adaptable office space with high visibility on Highway 75.

    101 Us Hwy 75, Denison, TX 75020

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    Versatile Office Space Available
    $4,000/Mo
    1,500 SF
    Versatile Office Space Available

    1500 sq ft office space suitable for multiple uses.

    13980 Fm 121, Van Alstyne, TX 75495

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    Denison Office Space For Rent
    $1,500/Mo
    2,135 SF
    Denison Office Space For Rent

    Move-in ready office space in a high-traffic Denison location.

    1110 S Armstrong Avenue, Denison, TX 75020

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    Sherman Office Suite For Rent
    $14 SF/Yr
    1,245 SF
    Sherman Office Suite For Rent

    Office suite in thriving plaza with highway access.

    200 E Evergreen Street, Sherman, TX 75090

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    West Sherman Office Suite
    $19 SF/Yr
    921 SF
    West Sherman Office Suite

    Garden-style office suite in West Sherman, built in 2019.

    2620 N Travis, Sherman, TX 75092

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    Medical Office Space For Lease
    $19 SF/Yr
    2,915 SF
    Medical Office Space For Lease

    Highly visible medical office space in a high-traffic area.

    3305 N Calais Drive, Sherman, TX 75090

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    Grayson County, TX Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Grayson County, TX with 28 listings featured on our commercial real estate exchange. The current inventory includes 98,519 square feet of properties with an estimated lease value of $278 SF/Yr.

    Estimated lease rates for Medical Office Space in Grayson County, TX begin at $2 SF/Yr, with an average of $17 SF/Yr and extend to $32 SF/Yr.
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