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Comal County, TX Medical Office Space for Lease

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99 results
Serene Office Park Setting
$16 SF/Yr
3,275 SF

Serene Office Park Setting

14855 Blanco Road, San Antonio, TX 78216

Office space in a well-located, highly visible office park.

  • Premier business environment in a serene office park setting.
  • Highly visible location at the Blanco and Bitters intersection.
  • Effortless access to 1604, 281, and Wurzbach Parkway.
  • Ample parking available.
  • Anchored by the well‑known Melting Pot Restaurant.
Updated: Mar 25
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Medical Office Space Near Hospital
$24 SF/Yr
7,000 SF

Medical Office Space Near Hospital

921 Lakeview Blvd, New Braunfels, TX 78130

Second-generation medical office space available near Christus Hospital.

  • Prime location, just 2‑3 blocks from Christus Hospital and Christus Santa Rosa Hospital.
  • Functional medical office space with approximately 3,500 SF, featuring multiple exam rooms, waiting rooms, and office space.
  • Second‑generation medical space ready for immediate use.
  • Elevator access provides easy access to the 2nd‑floor suite.
  • Ample parking available.
Updated: Nov 21, 2025
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Generations Drive Professional Office Space
$25 SF/Yr
5,294 SF

Generations Drive Professional Office Space

Shell space available in medical office development near Resolute Health.

790 Generations Drive, New Braunfels, TX 78130
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New Braunfels Medical/Office Space
$25 SF/Yr
13,411 SF

New Braunfels Medical/Office Space

Move-in ready office space near hospitals and major routes.

66 Gruene Park Dr, New Braunfels, TX 78130
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New Braunfels Medical/Professional Office Space
$36 SF/Yr
20,128 SF

New Braunfels Medical/Professional Office Space

New medical and professional office building for lease in New Braunfels.

671 Ridge Hill Dr, New Braunfels, TX 78130
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Class A Medical Office Space
$25 SF/Yr
18,600 SF

Class A Medical Office Space

New Class A medical/retail space for lease, ready for occupancy.

1750 East Common Street, New Braunfels, TX 78130
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Renovated Office Space in Oak Hills
$25 SF/Yr
4,540 SF

Renovated Office Space in Oak Hills

Medical/Office space for lease, convenient location, undergoing renovation.

1735 Babcock Rd, San Antonio, TX
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Medical Office on Broadway Street
$28 SF/Yr
2,515 SF

Medical Office on Broadway Street

Second-generation medical office space available for lease.

8005 Broadway St, San Antonio, TX
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Medical/Office Space Near Methodist Hospital
$18 SF/Yr

Medical/Office Space Near Methodist Hospital

Medical/office space available near Methodist Stone Oak Hospital.

116 Gallery Cir, San Antonio, TX 78258
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Medical Office Complex For Rent
Contact for pricing

Medical Office Complex For Rent

Seven-building medical office complex with flexible floor plans.

5360 Fredericksburg Rd, San Antonio, TX 78229
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Medical Office Space Available
Contact for pricing

Medical Office Space Available

Medical office complex with flexible floor plans and ample parking.

5364 Fredericksburg Rd, San Antonio, TX 78229
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Stone Oak Medical Office Space
Contact for pricing
1,701 SF

Stone Oak Medical Office Space

Second-generation medical office space in the Stone Oak market.

155 E Sonterra Blvd, San Antonio, TX 78258
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Medical Office Space Available
$18 SF/Yr
12,014 SF

Medical Office Space Available

Office space for rent near Methodist Stone Oak Hospital.

116 Gallery Cir, San Antonio, TX 78258
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Medical Office Space Available
Contact for pricing
3,741 SF

Medical Office Space Available

Class A medical office building near restaurants and retailers.

4103 N Loop 1604 W, San Antonio, TX 78249
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Medical Office Space Available
Contact for pricing
1,958 SF

Medical Office Space Available

Class A medical office building near restaurants and retailers.

7719 Interstate 35 S, San Antonio, TX 78224
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Medical Office Space Available
Contact for pricing
610 SF

Medical Office Space Available

Class A medical office building near hospital and university.

8230 N Loop 1604 W, San Antonio, TX 78249
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Turnkey Medical/Retail Space Available
Contact for pricing
17,047 SF

Turnkey Medical/Retail Space Available

Turnkey medical and second-generation retail space for lease.

6801 SAN PEDRO AVENUE, San Antonio, TX 78216
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Medical Office Space For Lease
Contact for pricing

Medical Office Space For Lease

First-floor medical office space with Loop 1604 visibility.

4515 N Loop 1604 W, San Antonio, TX 78249
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Medical/Office Space Available
Contact for pricing
554 SF

Medical/Office Space Available

554 SF medical/office space for rent.

7940 Floyd Curl Dr, San Antonio, TX 78229
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San Antonio Medical/Office Space
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1,823 SF

San Antonio Medical/Office Space

1823 SF medical/office space available for lease.

225 E Sonterra Blvd, San Antonio, TX 78258
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Office/Medical Office Space Available
Contact for pricing
5,078 SF

Office/Medical Office Space Available

Office and medical suites for lease with immediate occupancy.

876 Loop 337, New Braunfels, TX 78130
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Medical Office Space Available
$16 SF/Yr
12,342 SF

Medical Office Space Available

Move-in ready medical office space in San Antonio.

6623 S Zarzamora St, San Antonio, TX
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Versatile Space in New Braunfels
$28 SF/Yr
3,800 SF

Versatile Space in New Braunfels

Spacious property ideal for retail, office, or medical use.

901 Loop 337, New Braunfels, TX
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Turnkey Medical Space Available
$24 SF/Yr
1,720 SF

Turnkey Medical Space Available

Second-generation medical space in a vibrant trade area.

2327 Sw Military Dr, San Antonio, TX
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Comal County, TX Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Comal County, TX with 99 listings featured on our commercial real estate exchange. The current inventory includes 2,357,859,240 square feet of properties with an estimated lease value of $273 SF/Yr.

Estimated lease rates for Medical Office Space in Comal County, TX begin at $16 SF/Yr, with an average of $22 SF/Yr and extend to $28 SF/Yr.
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