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    Spring Branch, TX Medical Office Space for Lease

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    Bulverde, TX Canyon Lake, TX Boerne, TX Bergheim, TX New Braunfels, TX San Antonio, TX Garden Ridge, TX Schertz, TX
    Two-Building Medical Office Campus
    Updated: May 12
    Two-Building Medical Office Campus

    4800 US Highway 281 N, Spring Branch, TX 78070

    Contact for pricing
    13,736 sqft
    Two‑building medical/professional campus built in 1998 with approx. 13,736 SF total (Building 1: ±5,450 SF; Building 2: ±8,286 SF)
    Grey box delivery with studs and electrical in place; buildout to start after lease execution and availability upon buildout completion
    Lease terms available from 36 to 120 months; NNN asking rate $18.00–$24.00/SF/year plus estimated NNN expenses of $3.25/SF/year
    Estimated total occupancy cost: $21.25–$27.25/SF/year (NNN); TI negotiable with landlord preference for abated rent in lieu of cash allowance
    On‑site full‑size pool available for lease for potential aquatic therapy/rehabilitation or similar medical/wellness uses
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    Medical Office Buildings for Lease
    Updated: May 11
    Medical Office Buildings for Lease

    4800 US Hwy 281 N, Spring Branch, TX 78070

    Contact for pricing
    3,040 sqft
    Two demisable buildings: B1 ±1,450 SF and B2 ±8,286 SF (contiguous options available).
    Medical‑preferred use with anchor co‑tenancy: Medberry Primary Care on‑site.
    HWY 281 frontage on a high‑visibility Bulverde/Spring Branch corridor; 1 mile north of HWY 46.
    Full‑size pool space available for lease for physical therapy/aquatic rehab potential.
    36–120 month flexible lease terms; TI negotiable with abated rent structure.
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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 6 Potential Opportunities for your consideration. Besides 2 Active listings in Spring Branch, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office or Retail Suite
    Medical Office or Retail Suite

    2-1036 E Borgfeld Dr, San Antonio, TX 78260

    $4,000/Mo
    1,200 sqft 0.65 AC lot

    Approximately 1,500 sq-ft suite is available within a multi-tenant building, suited for medical office or retail use.

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    Dental Office and End Cap Retail
    Dental Office and End Cap Retail

    23522 Wilderness Oak, San Antonio, TX 78258

    Contact for pricing
    1,400 sqft

    Two 2nd-generation suites are available: 1,400 SF dental space and 1,300 SF end cap retail space.

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    Two Single-Story Office Buildings
    Two Single-Story Office Buildings

    21702 Encino Commons, San Antonio, TX 78259

    Contact for pricing
    12,000 sqft

    C-2 ERZD zoning; two single-story office buildings with Q2 2025 shell delivery and 3.5/1,000 SF parking.

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    Medical/Retail Space Under Construction
    Medical/Retail Space Under Construction

    2407 E Evans Rd, San Antonio, TX 78259

    Contact for pricing
    9,730 sqft

    Class A medical/retail space with high visibility, completion August 2023.

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    Spring Branch, TX Medical Office Space Lease Rates & Market Statistics

    Explore 2 Medical Office Space listings for lease in Spring Branch, TX on Realmo, a commercial real estate exchange covering the Spring Branch area. The current inventory totals 16,776 square feet of properties.

    Spring Branch accounts for 6% of the 35 medical office space listings currently available across Comal County, where nearby markets include New Braunfels and San Antonio. Medical Office Space is one of the more limited space types in Spring Branch, with just 2 listings currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (4 listings) elsewhere in the Spring Branch market.

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