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    Collin County, TX Medical Office Space for Lease

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    185 properties
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    Office Units with Reception Area
    Updated: Sep 1
    Office Units with Reception Area

    4512 Legacy Drive, Plano, TX 75024

    $7,235/Mo
    3,473 sqft 0.36 AC lot
    3,473‑square‑foot office property spanning Units 100 and 200
    Layout includes 5 private offices, 4 bathrooms, reception, break room, and storage
    2 large open work areas allow flexible workspace configurations
    Frontage on Legacy Drive at Legacy Drive and Preston Meadow Drive
    Reported drive‑by exposure exceeds 38,000 cars per day
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    Medical Office Suite with Exam Rooms
    Updated: Aug 11
    Medical Office Suite with Exam Rooms

    540 W Frontier Parkway, Prosper, TX 75078

    $4,206/Mo
    11,718 sqft 3.72 AC lot
    1,364 SF medical office suite with five private exam rooms
    Exam rooms include sinks and cabinetry; healthcare‑rated electrical lines serve the space
    Layout includes reception, private office, two storage closets, wet bar, and two full bathrooms
    Private entrance with 24‑hour access and accessible approach with ramp
    Located 0.3 miles from N. Preston Rd. and 2 miles from the Dallas Parkway and Dallas North Tollway
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    Medical Office End-Cap Suite
    Medical Office End-Cap Suite

    2120 Prairie Drive, Prosper, TX 75078

    $3,800/Mo
    2,374 sqft 0.05 AC lot

    Contiguous corner workspace with dedicated clinical plumbing, patient reception, private offices, and multiple restrooms.

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    Turnkey Office Suite with Break Room
    Turnkey Office Suite with Break Room

    Mckinney, TX 75070

    $23 SF/Yr
    2,500 sqft

    Turnkey double-suite office layout with open work area, two private offices, two restrooms, and a break room kitchen.

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    Second-Generation Medical Office Suite
    Second-Generation Medical Office Suite

    2145 W Park Boulevard, Plano, TX 75075

    $17 SF/Yr
    1,596 sqft 0.82 AC lot

    Configured for healthcare and wellness practices with reception, exam rooms, private offices, and administrative space.

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    New Office Suite
    New Office Suite

    2120 Prairie Drive, Prosper, TX 75078

    $35 SF/Yr
    1,187 sqft 5.58 AC lot

    Under-construction workspace includes central HVAC and contemporary architectural finishes.

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    Corner Office Unit with Medical Rough-Ins
    Corner Office Unit with Medical Rough-Ins

    1630 Prosper Trail, Prosper, TX 75078

    $3,500/Mo

    Unit 310 offers three private offices, reception, conference space, and a substantial kitchen break room.

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    Medical-Ready Office Unit
    Medical-Ready Office Unit

    8668 John Hickman Pkwy Unit 202, Frisco, TX 75034

    $2,800/Mo
    4,600 sqft

    Configured suite with private rooms, reception, conference space, break room, and medical plumbing rough-ins.

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    Suite 265 Medical Office with Exam Rooms
    Suite 265 Medical Office with Exam Rooms

    7300 Eldorado Parkway, Mckinney, TX 75070

    $4,054/Mo
    8.04 AC lot

    Move-in ready second generation medical office suite with reception, private offices, two exam rooms, and a private restroom.

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    NNN Office Condos Pre-Leasing
    NNN Office Condos Pre-Leasing

    512 N Oklahoma Drive, Celina, TX 75009

    $3,000/Mo
    2.30 AC lot

    Under-construction office condos delivered cold and dark shell with a NNN lease structure for flexible interior build-outs.

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    Office Unit with Private Offices
    Office Unit with Private Offices

    8765 Stockard Dr Unit 203, Frisco, TX 75034

    $995/Mo
    1,165 sqft

    Flexible office configuration with reception, conference space, and access to major Frisco tollways.

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    Second-Generation Medical Office Suite
    Second-Generation Medical Office Suite

    7300 Eldorado Parkway, Mckinney, TX 75070

    $4,415/Mo
    8.04 AC lot

    Move-in ready medical office suite with a reception area, multiple exam rooms, and private restroom in a dedicated medical building.

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    New Office Unit in Hays Office Park
    New Office Unit in Hays Office Park

    291 S Preston Road, Prosper, TX 75078

    $3,300/Mo

    Newer office unit in Hays Office Park with brick construction, central air, and on-site parking lot access.

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    End-Cap Medical Office Suite
    End-Cap Medical Office Suite

    2120 Prairie Dr Unit 901, Prosper, TX 75078

    $3,950/Mo
    1,187 sqft

    Brand-new 2026 end-cap suite with reception, conference, kitchen, private restroom, and three exam rooms.

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    Medical Office Space with 5 Offices
    Medical Office Space with 5 Offices

    150 Brand Road, Murphy, TX 75094

    $2,900/Mo
    1.21 AC lot

    Corner medical corridor setting with reception, kitchen, bathroom, and on-site parking lot.

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    Medical Office Suite End-Cap
    Medical Office Suite End-Cap

    2120 Prairie Drive, Prosper, TX 75078

    $3,950/Mo
    0.03 AC lot

    Brand-new 2026 end-cap medical office suite with a corner location, designed for patient flow and clinical sink-equipped exam rooms.

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    Corner Office Unit
    Corner Office Unit

    1630 Prosper Trail 310, Prosper, TX 75078

    $3,500/Mo
    1,350 sqft

    Medical-office-ready suite with private rooms, reception space, and substantial natural light.

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    Built-Out Office Unit
    Built-Out Office Unit

    3951 Alma Road, Mckinney, TX 75070

    $3,500/Mo
    0.01 AC lot

    Four private offices, reception area, kitchen breakroom, central HVAC, and accessible ramp support professional and medical office use.

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    Move-In Ready Office Unit
    Move-In Ready Office Unit

    3951 Alma Rd Unit 202, Mckinney, TX 75070

    $3,500/Mo
    1,225 sqft

    Built-out professional suite with private offices, reception space, and a kitchen breakroom for immediate occupancy.

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    Medical Office Shell Space
    Medical Office Shell Space

    8590 Stonebrook Parkway, Frisco, TX 75034

    $32 SF/Yr
    1.31 AC lot

    Under-construction space supports medical and general office buildouts with tenant improvement assistance available.

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    Medical Office Suite with ADA Access
    Medical Office Suite with ADA Access

    7700 Preston Rd Unit 902, Frisco, TX 75034

    $3,561/Mo
    1,187 sqft

    First-floor suite in a new medical office park with ADA-compliant access, high ceilings, and double-pane windows.

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    Office Units with Private Offices
    Office Units with Private Offices

    8765 Stockard Drive, Frisco, TX 75034

    $995/Mo
    0.03 AC lot

    Flexible office layout includes reception, conference space, and shared common areas near major tollways.

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    Move-In Ready Medical Office Space
    Move-In Ready Medical Office Space

    7300 Eldorado Pkwy Unit 265, Mckinney, TX 75070

    $4,054/Mo
    1,497 sqft

    Configured with reception, private offices, exam rooms, staff area, and a private restroom.

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    Office Units with Preston Road Frontage
    Office Units with Preston Road Frontage

    7700 Preston Road, Frisco, TX 75034

    $3,495/Mo
    3.61 AC lot

    Under-construction office units offer accessible customer parking and a flexible setting for service-oriented businesses.

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    Collin County, TX Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Collin County, TX with 185 listings featured on our commercial real estate exchange. The current inventory includes 941,420 square feet of properties with an estimated lease value of $1,273.

    Estimated lease rates for Medical Office Space in Collin County, TX begin at $1.71 SF/Yr, with an average of $28.29 SF/Yr and extend to $40 SF/Yr.
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    Featured Collin County Real Estate Agencies

    Realmo connects you with licensed Collin County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Allie Beth Allman and Associates
    5037 Tracy Street Dallas, TX 75205
    Phone: 12145282500
    alliebeth.com
    Keller Williams North Country
    1212 S Preston Road, Ste 120 Celina, TX 75009
    Phone: 19723828882
    www.kwnorthcountry.com/
    Keller Williams Frisco Stars
    4783 Preston Road, Suite 100 Frisco, TX 75034
    Phone: 19727129898
    www.kwfrisco.com

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