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Prosper, TX

Medical Space

Prosper, TX Medical Office Space for Lease

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Frisco, TX Celina, TX Mckinney, TX Little Elm, TX The Colony, TX Arlington, TX Aubrey, TX Addison, TX

9 properties

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Medical Office with Exam Rooms

Updated: Aug 11

Medical Office with Exam Rooms

540 W Frontier Parkway, Prosper, TX 75078

$4,092/Mo

11,718 sqft 3.72 AC lot

1,364‑square‑foot suite with five private exam rooms, each fitted with a sink and cabinetry
Includes reception, private office, two storage closets, wet bar, and two full bathrooms
Private entrance with 24‑hour access and an accessible approach with ramp
0.3 miles from N. Preston Road; 2 miles from the Dallas Parkway and Dallas North Tollway
3 miles from Gates of Prosper Shopping Center

Medical Office End-Cap Suite

Updated: Jun 18

Medical Office End-Cap Suite

2120 Prairie Drive, Prosper, TX 75078

$3,800/Mo

2,374 sqft 0.05 AC lot

2,374‑square‑foot contiguous medical office suite combining Units 901 and 902
Corner end‑cap position in Building One at 2120 Prairie Drive, Prosper
Up to four exam rooms with dedicated sinks
Reception area, conference rooms, two kitchens, private offices, and multiple restrooms
Access to the Dallas North Tollway and HWY 380

Corner Office Unit with Medical Rough-Ins

Corner Office Unit with Medical Rough-Ins

1630 Prosper Trail, Prosper, TX 75078

$3,500/Mo

Unit 310 offers three private offices, reception, conference space, and a substantial kitchen break room.

End-Cap Medical Office Suite

End-Cap Medical Office Suite

2120 Prairie Dr Unit 901, Prosper, TX 75078

$3,950/Mo

1,187 sqft

Brand-new 2026 end-cap suite with reception, conference, kitchen, private restroom, and three exam rooms.

End-Cap Medical Office Suite

End-Cap Medical Office Suite

2120 Prairie Drive, Prosper, TX 75078

$3,950/Mo

0.03 AC lot

Medical-use suite with three exam rooms, clinical sinks, natural light, and direct access to major regional routes.

Corner Office Unit

Corner Office Unit

1630 Prosper Trail 310, Prosper, TX 75078

$3,500/Mo

1,350 sqft

Medical-office-ready suite with private rooms, reception space, and substantial natural light.

End-Cap Corner Medical Office Suite

End-Cap Corner Medical Office Suite

2120 Prairie Drive 901, Prosper, TX 75078

$3,950/Mo

New 2026 end-cap medical suite with a corner position, reception, conference room, private restroom, kitchen, and three exam rooms.

Fully Built-Out Office Condo Suite

Fully Built-Out Office Condo Suite

291 S Preston Road 420, Prosper, TX 75078

$3,200/Mo

Move-in ready office suite with private offices, open work areas, and reception, built in 2023 with an NNN lease structure.

Medical Office End-Cap Suite

Medical Office End-Cap Suite

2120 Prairie Drive, Unit #901, Prosper, TX 75078

Contact for pricing

2,374 sqft

New 2,374 SF medical suite in Prosper, TX for lease.

Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 9 Active listings in Prosper, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Brand-New Mixed-Use Retail Center

10402 Coit Rd, Frisco, TX 75035

$40 SF/Yr

20,000 sqft

Brand-new shell spaces support office, medical, retail, and service uses with customizable layouts.

Medical Office Suite with Exam Rooms

Medical Office Suite with Exam Rooms

1400 N Coit Road, Mckinney, TX 75071

$4,600/Mo

13.30 AC lot

A first-floor, fully built-out suite includes plumbing and sinks for clinical use.

Corner Medical Office Suite

Corner Medical Office Suite

1400 N Coit Road, Mckinney, TX 75071

$4,100/Mo

13.30 AC lot

The completed first-floor layout has carpet and vinyl flooring, central heating, and central air conditioning.

Professional Medical Office Suites

Professional Medical Office Suites

11005 Preston Rd, Frisco, TX 75033

Contact for pricing

1,797 sqft

Two-story professional and medical office building offers suites for custom finish-out starting August 2025.

Similar Spaces for Sale in Prosper, TX

Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

Medical Office End-Cap Suite

Medical Office End-Cap Suite

2120 Prairie Drive Unit #901, Prosper, TX 75078

$569,000

1,187 sqft

Newly completed clinical suite with exam rooms, dedicated sinks, and access to major regional routes.

End-Cap Medical Office Suite

End-Cap Medical Office Suite

2120 Prairie Drive, Prosper, TX 75078

$569,000

0.03 AC lot

Medical-use suite with exam rooms, reception, consultation space, and dedicated clinical sinks.

Medical Office End-Cap Suite

Medical Office End-Cap Suite

2120 Prairie Drive, Prosper, TX 75078

$1,044,000

0.05 AC lot

Contiguous layout includes reception, consultation, exam, office, kitchen, and restroom areas.

New Medical Office Suite

New Medical Office Suite

540 W Frontier Parkway, Prosper, TX 75078

Contact for pricing

11,718 sqft

Five exam rooms, two bathrooms, and a private entrance support clinical operations.

End-Cap Medical Office Suite

End-Cap Medical Office Suite

901-2120 Prairie Dr, Prosper, TX 75078

Contact for pricing

1,187 sqft

Brand-new 2026 end-cap suite with reception, conference room, kitchen, restroom, and three exam rooms.

Medical Office Suite in Office Park

Medical Office Suite in Office Park

291 S Preston Road Unit 610, Prosper, TX 75078

Contact for pricing

1,220 sqft

Nearly new 1,220-sf office suite within Hays Office Park, positioned on the NE corner of Preston Road and East First Street.

Move-In Ready Office Condo Suite

Move-In Ready Office Condo Suite

420-291 S Preston Rd, Prosper, TX 75078

$550,000

Fully finished office suite with private offices, open work areas, and reception space.

Medical Office End-Cap Suite

Medical Office End-Cap Suite

2120 Prairie Drive #901 & 902, Prosper, TX 75078

$1,044,000

2,374 sqft

Configured for medical operations with exam rooms, private offices, and dedicated clinical sinks.

Prosper, TX Medical Office Space Lease Rates & Market Statistics

Explore 9 Medical Office Space listings for lease in Prosper, TX on Realmo, a commercial real estate exchange covering the Prosper area. The current inventory totals 19,003 square feet of properties.

Asking lease rates for Medical Office Space in Prosper start at $4.19 SF/Yr, average $23.61 SF/Yr, and reach $39.93 SF/Yr at the top of the market. That's a 10x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $23.61 SF/Yr is in line with the Texas state average.

Prosper accounts for 7% of the 135 medical office space listings currently available across Collin County, where nearby markets include Mckinney and Frisco. Medical Office Space listings make up 32% of the 28 Office Spaces currently for lease in Prosper, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Office Units (25 listings) elsewhere in the Prosper market.

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