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    Frisco, TX Medical Office Space for Lease

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    Dallas, TX San Antonio, TX Austin, TX
    22 results
    Frisco Office/Medical Building For Lease
    $8,167 /Mo

    Frisco Office/Medical Building For Lease

    425 Old Newman Road, Frisco, TX 75036

    Move-in ready office/medical building in Frisco, TX available for lease.

    • Ready to move in, fully equipped professional office/medical building (3,630 sqft) suitable for immediate occupancy.
    • Ideally located in a large professional complex in Frisco, TX, adjacent to Phillips Creek Ranch and with direct exposure on FM 423.
    • Designed for optimal functionality with separate areas for physicians/administration and exam rooms, plus separate entrances for well and sick patients.
    • Includes 9 exam rooms, 5 offices, admin room, break room, nurses' station, and two reception areas.
    • Owner is open to subdividing the space to accommodate smaller space requirements.
    Updated: Jan 29
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    Turnkey Office Space in Frisco
    $1,995 /Mo

    Turnkey Office Space in Frisco

    8765 Stockard Drive, Frisco, TX 75034

    Prime Frisco location, flexible floor plan, easy highway access.

    • Prime Frisco location with easy access to Dallas North Tollway (DNT) and Sam Rayburn Tollway (121).
    • Turnkey commercial office space ready for immediate occupancy.
    • Flexible floor plan with private offices, reception area, and conference room.
    • Suitable for a variety of professional uses including medical, legal, accounting, insurance, and coaching centers.
    • Close proximity to retail, restaurants, entertainment, and sporting venues.
    Updated: Dec 20, 2025
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    New Mixed-Use Retail Space
    $40 SF/Yr

    New Mixed-Use Retail Space

    Brand-new retail and office spaces in a prime Frisco location.

    10402 Coit Road, Frisco, TX 75035
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    Frisco Retail/Medical Space Available
    $32 SF/Yr

    Frisco Retail/Medical Space Available

    Shell space in prime location, suitable for medical or office uses.

    8590 Stonebrook Parkway, Frisco, TX 75034
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    Modern Medical Office in Frisco
    $30 SF/Yr

    Modern Medical Office in Frisco

    3,106 SF medical office space available for sublease or assignment.

    16100 STATE HIGHWAY 121 Highway S, Frisco, TX 75035
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    Move-in Ready Office/Medical Space
    $6,405 /Mo

    Move-in Ready Office/Medical Space

    Modern office/medical space with high ceilings and abundant natural light.

    10004 Coit Road, Frisco, TX 75035
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    Frisco Office Space For Lease
    $7,827 /Mo

    Frisco Office Space For Lease

    Office space suitable for office, medical, or salon use.

    7010 Ash Street, Frisco, TX 75034
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    Mixed-Use Retail & Restaurant Space
    Contact for pricing

    Mixed-Use Retail & Restaurant Space

    Two-story professional/medical buildings with retail and restaurant component for lease.

    12983 Main St, Frisco, TX 75035
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    Medical Office Space Near Hospital
    $32 SF/Yr
    1,930 SF

    Medical Office Space Near Hospital

    Class A medical office space available for lease.

    12500 Lebanon Rd, Frisco, TX
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    Frisco Office/Medical Space For Lease
    $3,300 /Mo
    1,150 SF

    Frisco Office/Medical Space For Lease

    Newly built office space in a high-traffic Frisco location.

    400 Stonebrook Pkwy Spc 1103, Frisco, TX 75036
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    Medical Office Space in Frisco
    Contact for pricing

    Medical Office Space in Frisco

    Premier medical office space connected to Baylor Scott & White.

    4401 Coit Rd, Frisco, TX 75035
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    Medical Office Connected to Hospital
    Contact for pricing
    1,371 SF

    Medical Office Connected to Hospital

    Medical office space connected to Baylor Scott & White Medical Center.

    5575 Warren Pkwy, Frisco, TX
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    Frisco Office Space For Lease
    Contact for pricing
    1,526 SF

    Frisco Office Space For Lease

    Office condos available for lease in Frisco, Texas.

    US 380 & Hollyhock Rd, Frisco, TX
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    Medical Office Space Available
    Contact for pricing
    23,000 SF

    Medical Office Space Available

    Medical office space for rent with hospital access.

    7600 Better Way, Frisco, TX
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    Class A Office Space Available
    Contact for pricing
    6,980 SF

    Class A Office Space Available

    Customizable Class A office space for rent in Frisco.

    12850 Dallas Pkwy, Frisco, TX
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    Medical Office Space For Rent
    Contact for pricing
    2,897 SF

    Medical Office Space For Rent

    Medical office space with hospital connection in growing DFW area.

    4461 Coit Rd, Frisco, TX
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    Class-A Medical Office in Frisco
    Contact for pricing
    60,000 SF

    Class-A Medical Office in Frisco

    Premier medical office building with exceptional visibility and accessibility.

    12850 Dallas Pkwy, Frisco, TX 75033
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    Retail and Medical Office Space
    Contact for pricing
    38,000 SF

    Retail and Medical Office Space

    38,000 SF retail/medical space near Windsong Ranch and PGA.

    16702 Hollyhock Rd, Frisco, TX
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    Frisco Dental Space Available
    Contact for pricing
    1,800 SF

    Frisco Dental Space Available

    1,800 SF second-generation dental space for lease.

    11501 Custer Rd, Frisco, TX
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    Medical and Sports Research Center
    Contact for pricing
    6,162 SF

    Medical and Sports Research Center

    World-class sports therapy and research center in Frisco, Texas.

    3800 Gaylord Pkwy, Frisco, TX
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    Prime Frisco Shell Space Available
    Contact for pricing
    5,500 SF

    Prime Frisco Shell Space Available

    Shell space in prime location suitable for medical or office.

    8590 Stonebrook Pkwy, Frisco, TX 75034
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    New Office/Medical Building Available
    Contact for pricing
    4,875 SF

    New Office/Medical Building Available

    New office/medical building with ample tenant improvements, delivered in 2025.

    11619 Independence Pkwy, Frisco, TX 75035
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    Based on your search, we've compiled 41 Potential Opportunities for your consideration. Besides 22 Active listings in Frisco, TX, we suggest exploring alternatives. Similar 19 Properties for Sales.

    Explore Similar Spaces for Sale in Frisco, TX

    Consider Similar Space for Sale. We found 19 Spaces matching your search parameters.

    Frisco Office Condo For Sale
    $709,000
    1,542 SF

    Frisco Office Condo For Sale

    1,542 SF office condo in prime Frisco location.

    11619 Independence Parkway, Frisco, TX 75035
    View details
    Prime Commercial Land in Frisco
    $5,245,000
    2.44 Acres

    Prime Commercial Land in Frisco

    High-visibility land suitable for retail, medical, restaurant, or mixed-use development.

    4400 Preston Road, Frisco, TX 75034
    View details

    Frisco, TX Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Frisco, TX with 22 listings featured on our commercial real estate exchange. The current inventory includes 17,099,652,974 square feet of properties with an estimated lease value of $171 SF/Yr.

    Estimated lease rates for Medical Office Space in Frisco, TX begin at $0.83 SF/Yr, with an average of $24 SF/Yr and extend to $40 SF/Yr.
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    Browse Medical Office Space for Lease Near Frisco, TX

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