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    Wylie, TX Medical Office Space for Lease

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    Medical Office Space with Monument Signage
    Updated: Jan 31, 2025
    Medical Office Space with Monument Signage

    2300 W FM 544, Wylie, TX 75098

    Contact for pricing
    1,659 sqft
    Class A medical office space with spec suite, shell, and 2nd gen medical options
    Anchored by Baylor Scott & White Emergency Center
    Monument and building signage available
    Located at 2300 W FM 544, Wylie, TX 75098
    Parking indicated at 3.85:1000
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    Medical Office Space Available
    Updated: Nov 24, 2025
    Medical Office Space Available

    600 Cooper Drive, Wylie, TX 75098

    Contact for pricing
    2nd generation medical buildout available, saving you time and money.
    Excellent tenant mix including Orthodontist, Physical Therapy, and Primary Care.
    Easy access to Texas HWY 78.
    Close to retail amenities.
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    Medical Office Space Available
    Medical Office Space Available

    2300 W FM 544, Wylie, TX

    Contact for pricing
    1,852 sqft 3.30 AC lot

    Class A medical office space anchored by Baylor Scott & White.

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    Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 3 Active listings in Wylie, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Suite with Signage
    Medical Office Suite with Signage

    3443 East Renner Road, Ste 110, Plano, TX 75074

    $25 SF/Yr
    2,970 sqft

    Shell-condition professional space offers a tenant improvement package, monument signage, and building signage options.

    View details
    Medical Office Space with 5 Offices
    Medical Office Space with 5 Offices

    150 Brand Road, Murphy, TX 75094

    $2,900/Mo
    1.21 AC lot

    Corner medical corridor setting with reception, kitchen, bathroom, and on-site parking lot.

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    Medical Office Suite with Signage
    Medical Office Suite with Signage

    1020 N Murphy Rd, Murphy, TX 75094

    Contact for pricing
    2,000 sqft

    Suite 200 supports medical and professional office uses near major retail anchors.

    View details
    Finished Office Unit
    Finished Office Unit

    525 Shiloh Rd, Plano, TX 75074

    Contact for pricing
    1,200 sqft

    New professional office space with completed interiors, immediate occupancy, and building and monument signage opportunities.

    View details

    Similar Spaces for Sale in Wylie, TX

    Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

    Commercial Land
    Commercial Land

    801 S State Highway 78, Wylie, TX 75098

    Contact for pricing

    The site fronts SH 78 and previously accommodated hospital and medical office uses.

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    Wylie, TX Medical Office Space Lease Rates & Market Statistics

    Explore 3 Medical Office Space listings for lease in Wylie, TX on Realmo, a commercial real estate exchange covering the Wylie area. The current inventory totals 3,511 square feet of properties.

    Wylie accounts for 2% of the 134 medical office space listings currently available across Collin County, where nearby markets include Mckinney and Frisco. Medical Office Space is one of the more limited space types in Wylie, with just 3 listings currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (8 listings) elsewhere in the Wylie market.

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    Browse Medical Office Space for Lease Near Wylie, TX

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    Most Searched ZIP Codes in Wylie, TX

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    Featured Wylie Real Estate Agencies

    Realmo connects you with licensed Wylie CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Lori Woodworth
    2111 Fair Park Lane Wylie, TX
    Phone: (214) 727-1659
    HSN Realty, LLC
    413 Fleming St Wylie, TX 75098
    Phone: (214) 263-6530
    www.hsnrealtyllc.com/
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