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    Wylie, TX Medical Office Space for Lease

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    Medical Office Space with Monument Signage
    Updated: Jan 31, 2025
    Medical Office Space with Monument Signage

    2300 W FM 544, Wylie, TX 75098

    Contact for pricing
    1,659 sqft
    Class A medical office space with spec suite, shell, and 2nd gen medical options
    Anchored by Baylor Scott & White Emergency Center
    Monument and building signage available
    Located at 2300 W FM 544, Wylie, TX 75098
    Parking indicated at 3.85:1000
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    Medical Office Space Available
    Updated: Nov 24, 2025
    Medical Office Space Available

    600 Cooper Drive, Wylie, TX 75098

    Contact for pricing
    2nd generation medical buildout available, saving you time and money.
    Excellent tenant mix including Orthodontist, Physical Therapy, and Primary Care.
    Easy access to Texas HWY 78.
    Close to retail amenities.
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    Medical Office Space Available
    Medical Office Space Available

    2300 W FM 544, Wylie, TX

    Contact for pricing
    1,852 sqft 3.30 AC lot

    Class A medical office space anchored by Baylor Scott & White.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 7 Potential Opportunities for your consideration. Besides 3 Active listings in Wylie, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space with 5 Offices
    Medical Office Space with 5 Offices

    150 Brand Road, Murphy, TX 75094

    $2,900/Mo
    1.21 AC lot

    Corner medical corridor setting with reception, kitchen, bathroom, and on-site parking lot.

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    Medical Office Suite with Signage
    Medical Office Suite with Signage

    1020 N Murphy Rd, Murphy, TX 75094

    Contact for pricing
    2,000 sqft

    Suite 200 supports medical and professional office uses near major retail anchors.

    View details
    Medical Office Building for Lease
    Medical Office Building for Lease

    4650 President George Bush Hwy, Sachse, TX 75048

    Contact for pricing
    5,065 sqft 25.00 AC lot

    New medical office building in a larger medical campus that also includes a hospital.

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    Medical Office Building For Rent
    Medical Office Building For Rent

    4650 President George Bush Hwy, Sachse, TX

    Contact for pricing
    18,833 sqft 4.27 AC lot

    New medical office building in fast-growing, underserved Dallas area.

    View details

    Wylie, TX Medical Office Space Lease Rates & Market Statistics

    Explore 3 Medical Office Space listings for lease in Wylie, TX on Realmo, a commercial real estate exchange covering the Wylie area. The current inventory totals 3,511 square feet of properties.

    Wylie accounts for 2% of the 161 medical office space listings currently available across Collin County, where nearby markets include Plano and Mckinney. Medical Office Space is one of the more limited space types in Wylie, with just 3 listings currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (11 listings) elsewhere in the Wylie market.

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