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    Missouri Medical Office Space for Lease

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    Kansas City, MO Saint Louis, MO Springfield, MO Joplin, MO Saint Charles, MO Chesterfield, MO Louis, MO St Joseph, MO
    117 properties
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    New Construction Retail Space
    Updated: Jul 30
    New Construction Retail Space

    13225 Jay Drive, Neosho, MO 64850

    $12 SF/Yr
    1,600 sqft
    1,600‑square‑foot newly constructed retail space
    White‑box delivery condition supports a flexible interior buildout
    Two restrooms included within the premises
    Central air conditioning and electric heating
    Concrete flooring and metal roof
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    Remodeled Medical Office Suite
    Updated: May 6
    Remodeled Medical Office Suite

    2650 E 32nd Street, Joplin, MO 64804

    $12 SF/Yr
    3,300 sqft 1.87 AC lot
    3,300 SF first‑floor medical office suite
    Remodeled in 2024
    Four private offices and two in‑suite restrooms
    Two private flex rooms, two open areas, and multiple storage closets
    Suite may be subdivided into two separate spaces
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    Updated Professional Office Suite
    Updated Professional Office Suite

    1531 W 32nd Street, Joplin, MO 64804

    $1,175/Mo
    1,185 sqft 2.73 AC lot

    Flexible office layout with private rooms, shared work areas, a conference room, and an accessible private restroom.

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    Flexible Church-Built Retail/Office Space
    Flexible Church-Built Retail/Office Space

    25 Winfield Manor Dr, Winfield, MO 63389

    $1,200/Mo
    6,000 sqft

    A 6,000± SF suite with existing church buildout and flexible layout in Winfield Plaza.

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    Multi-Room Office Units
    Multi-Room Office Units

    605 Fir Road, Carl Junction, MO 64834

    $1,675/Mo
    1,900 sqft

    Flexible professional workspace with waiting areas, two bathrooms, a kitchen, and convenient access from a main road.

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    Renovated Stand-Alone Office Building
    Renovated Stand-Alone Office Building

    307 E 23rd Street, Independence, MO 64055

    $2,485/Mo
    0.20 AC lot

    C-2 space includes work areas, a break room, restrooms, and lower-level storage.

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    Professional Office Unit with Private Offices
    Professional Office Unit with Private Offices

    410 Remington Plaza Court, Raymore, MO 64083

    $3,300/Mo
    0.71 AC lot

    Flexible commercial workspace includes a reception area, conference room, restrooms, and break room for professional operations.

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    Medical Office Suite With Exam Rooms
    Medical Office Suite With Exam Rooms

    4955 S National Ave, Springfield, MO 65810

    $18 SF/Yr
    1,799 sqft 1.02 AC lot

    Suite B offers reception, four exam rooms, and support areas within a multi-tenant medical office property.

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    Medical Office Building with Dual Entrances
    Medical Office Building with Dual Entrances

    104 Sarah Ann Boulevard, Troy, MO 63379

    $3,000/Mo

    Flexible layout includes separate lobby areas, exam rooms, restrooms, and kitchen space.

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    Medical Office Space with Open Layout
    Medical Office Space with Open Layout

    3999 Highway PP Suite 3, Poplar Bluff, MO 63901

    $6,000/Mo
    0.72 AC lot

    Open-plan commercial space with central air, electric heat, and on-site lot parking.

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    Built-Out Office Suite
    Built-Out Office Suite

    151-186 South Dr, Branson, MO 65616

    $16 SF/Yr
    2,400 sqft

    Professional suite with private offices, meeting space, and an open collaborative work area.

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    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    14974 Us-160, Forsyth, MO 65653

    $1,800/Mo
    2.70 AC lot

    Configured healthcare space in a plaza setting with reception, patient waiting, exam, break, and restroom areas.

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    Medical Office Building
    Medical Office Building

    6944 N Hanley Road, Hazelwood, MO 63042

    $5,000/Mo
    2.28 AC lot

    Former bank building adapted for medical office use with flexible interior spaces.

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    Medical Office Suite with Drive-Thru
    Medical Office Suite with Drive-Thru

    6-14974 Us-160, Forsyth, MO 65653

    $1,800/Mo
    2,000 sqft

    Medical office suite with reception, waiting room, multiple exam rooms, and break room, with additional space and drive-thru available.

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    Medical Office Space with Operatories
    Medical Office Space with Operatories

    Saint Charles, MO 63303

    $19 SF/Yr
    1.59 AC lot

    Clinical layout includes reception, private offices, lab rooms, storage, patient amenities, and zoned HVAC.

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    Updated Office Suite with Medical Layout
    Updated Office Suite with Medical Layout

    1711 1743 S 15th Street, Ozark, MO 65721

    $3,425/Mo
    0.96 AC lot

    Multiple offices, collaborative work areas, meeting space, kitchenette, and restrooms accommodate varied business operations.

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    Class A Mixed-Use Building
    Class A Mixed-Use Building

    16721-16759 Main Street, Grover, MO 63040

    $23 SF/Yr
    4,818 sqft

    Medical/Office space for lease in Wildwood Town Center.

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    Renovated Second-Floor Medical Office
    Renovated Second-Floor Medical Office

    3916 S Lynn Court, Independence, MO 64055

    $10 SF/Yr
    0.36 AC lot

    Office and laboratory space with updated paint and flooring for dental or medical use.

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    Medical Mile Office Space
    Medical Mile Office Space

    3800 S Fremont, Springfield, MO 65804

    $500/Mo
    7,953 sqft

    Individual offices available for lease in medical mile.

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    Class B Medical Office Suite
    Class B Medical Office Suite

    2734 E Sunshine Street, Springfield, MO 65804

    $85,322/Mo
    1.27 AC lot

    Functional healthcare layout with extensive plumbing, support areas, and on-site parking along a heavily traveled corridor.

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    East Sunshine Office and Dental Suites
    East Sunshine Office and Dental Suites

    3259 E Sunshine St, Springfield, MO 65804

    $14.50 SF/Yr
    40,000 sqft

    Office and dental suites for lease in Sunshine Business Center.

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    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    1011 E Saint Maartens Drive, St Joseph, MO 64506

    $14 SF/Yr
    0.63 AC lot

    Office suite with client reception, plumbed appointment rooms, executive suites, and shared breakroom access.

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    Creve Coeur Office Building
    Creve Coeur Office Building

    Saint Louis, MO 63141

    $24 SF/Yr
    32,461 sqft

    Office building in thriving business district with convenient amenities.

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    Main-Level Medical Office Space
    Main-Level Medical Office Space

    1531 W 32nd Street, Joplin, MO 64804

    $700/Mo
    700 sqft 3.00 AC lot

    Main-level suite combines lab space with additional offices and includes utilities other than internet service.

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    Missouri Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Missouri with 117 listings featured on our commercial real estate exchange. The current inventory includes 496,415 square feet of properties with an estimated lease value of $282.18.

    Estimated lease rates for Medical Office Space in Missouri begin at $2.40 SF/Yr, with an average of $13.44 SF/Yr and extend to $24 SF/Yr.
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