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    Lafayette County, MO Medical Office Space for Lease

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    Two-Story Medical Office Suites
    Updated: Dec 18, 2025
    Two-Story Medical Office Suites

    316 W US Hwy 40, Odessa, MO 64076

    Contact for pricing
    1,750 sqft 1.75 AC lot
    11,000 SF, two‑story building on a 1.75‑acre lot
    Lower‑level office spaces for rent: 1,750 SF and 2,200 SF
    Street level is 100% occupied by a Medical Group and a Nail Salon
    Ample on‑site parking plus room to add an additional building
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    1 active listing matches your search: Medical Office for lease in Lafayette County, MO. Based on your search, we've also compiled 2 Potential Opportunities for your consideration: 2 properties for sale.

    Similar Spaces for Sale in Lafayette County, MO

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Renovated Medical Office Building
    Renovated Medical Office Building

    1717 N Main Street, Higginsville, MO 64037

    $399,000
    7,100 sqft

    Fully renovated medical office building with multiple exam rooms, reception, staff workspaces, and four bathrooms.

    View details
    Two-Story Brick Medical Office Building
    Two-Story Brick Medical Office Building

    316 W US Hwy 40, Odessa, MO 64076

    Contact for pricing
    11,000 sqft

    All-brick two-story building with available first-floor office space and an occupied second floor.

    View details

    Lafayette County, MO Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Lafayette County, MO with 1 listings featured on our commercial real estate exchange. The current inventory includes 1,750 square feet of properties.
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    Featured Lafayette County Real Estate Agencies

    Realmo connects you with licensed Lafayette County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    RE/MAX Central
    2817 Hwy 13 Higginsville, MO
    Phone: (660) 584-5557
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