Smithville, MO Medical Office Space for Rent & Lease

Updated: Oct 30, 2025

Flexible Retail-Office Medical Space

1501 S Us Highway 169, Smithville, MO 64089

Contact for pricing

1,400 sqft

Full building renovation underway with delivery expected early 2026
Flexible lease space suitable for retail, office, medical, or professional uses
Updated building systems and modernized interiors
Enhanced exterior and curb appeal
High‑visibility location in the heart of Smithville, MO

View details

Updated: Oct 30, 2025

Retail Space Under Full Renovation

1501 S Us Highway 169, Smithville, MO 64089

Contact for pricing

2,100 sqft

Full building renovation underway, delivery expected early 2026
Flexible lease space suitable for retail, office, medical, or professional uses
Updated building systems and modernized interiors
Enhanced exterior and curb appeal
Ample parking on site

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 2 Active listings in Smithville, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Executive Hills Office/Medical Building

10015 N. AMBASSADOR DR., Kansas City, MO 64154

$14 SF/Yr

39,840 sqft

Office/Medical building in Executive Hills with excellent I-29 access.

View details

Independence, MO - Office/Lab Space

3916 S Lynn Court, Independence, MO 64055

$10 SF/Yr

Recently renovated 2nd-floor office/lab space suitable for medical or dental.

View details

Medical Clinic in Office Building

300 N Osage St, Independence, MO 64050

Contact for pricing

5,270 sqft

Move-in ready second-floor medical clinic offers 13 exam rooms, lab space, and private offices in a well-maintained building.

View details

Medical-Ready Office Suite

9593 N McGee St, Kansas City, MO 64155

Contact for pricing

Office suite includes open work area, three private offices, kitchenette, and restrooms in a two-tenant building near Starbucks.

View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Office Development Land For Lease

1323 Strawfloor Drive, Jonesboro, AR 72401

Contact for pricing

4,000 sqft

2.43 acres for office development with build-to-suit opportunity.

View details

Corner Lot on Highway 72

30472 Highway 72, Madison, AL 35756

$5,000/Mo

1,875 sqft

1.7 acre corner lot zoned for commercial, medical, residential.

View details

Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

Contact for pricing

Outlot for ground lease or build-to-suit in South Lexington.

View details

Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 acre interstate-visible land for ground lease or build-to-suit.

View details

Smithville, MO Medical Office Space for Lease

1501 S Us Highway 169, Smithville, MO 64089

1501 S Us Highway 169, Smithville, MO 64089