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    Independence, MO Medical Office Space for Lease

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    Saint Louis, MO Louis, MO Kansas City, MO
    Retail/Medical Space on Highway 40
    Contact for pricing
    1,600 SF

    Retail/Medical Space on Highway 40

    17000 E US Hwy 40, Independence, MO

    Retail or medical spaces available for lease on Highway 40.

    • Located less than 1‑mile from Hwy 291/I‑470 Interchange.
    • Ample Parking: 3.7/1000 SF.
    • 1,600 - 5,372 SF available for lease.
    • Ideal for medical, special use, or retail users.
    • Under new ownership.
    Updated: Nov 4, 2025
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    Medical Office Space Available
    $1,900 /Mo
    1,200 SF

    Medical Office Space Available

    3800 S Elizabeth St, Independence, MO

    2700 SF medical office with multiple exam/office rooms.

    • 2700 sq ft of versatile space suitable for office or medical use.
    • Six rooms adaptable as exam rooms or private offices.
    • Large office connected to an exam room.
    • Restroom on‑site.
    • Storage rooms available.
    Updated: May 10, 2024
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    Medical Office Space For Rent
    Contact for pricing
    5,276 SF

    Medical Office Space For Rent

    Medical office space with hospital access and ample parking.

    19550-19600 E 39th St S, Independence, MO
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    Medical Office Space Available
    Contact for pricing
    2,700 SF

    Medical Office Space Available

    2700 sq ft medical office with multiple rooms.

    3800 South Elizabeth Street, Independence, MO 64057
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    Scottsdale Center Retail Opportunity
    Contact for pricing
    4,800 SF

    Scottsdale Center Retail Opportunity

    Retail space available in Scottsdale Center, Independence, Missouri.

    17020 E US Hwy 40, Independence, MO 64055
    View details
    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 5 Active listings in Independence, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space For Lease
    $25 SF/Yr
    6,560 SF

    Medical Office Space For Lease

    Class B medical office building with attractive clinic setting.

    3601 NE Ralph Powell Rd, Lees Summit, MO
    View details
    Blue Springs Medical Office Space
    $12 SF/Yr
    2,427 SF

    Blue Springs Medical Office Space

    Medical office space featuring procedure rooms and private restrooms.

    1701 SW US Hwy 40, Blue Springs, MO
    View details
    Medical Office Space Available
    Contact for pricing
    4,350 SF

    Medical Office Space Available

    Class A medical office space for lease with exam rooms.

    Lees Summit, MO 64064
    View details
    Medical Office Space For Rent
    Contact for pricing
    10,006 SF

    Medical Office Space For Rent

    Medical office space available within Saint Mary’s Medical Center campus.

    205 NW R D Mize Rd, Blue Springs, MO 64014
    View details

    Explore Similar Spaces for Sale in Independence, MO

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Independence Office Building For Sale
    $3,100,000
    1.60 Acres

    Independence Office Building For Sale

    Office building with freeway visibility and strong retail anchors.

    20101 E JACKSON Drive, Independence, MO 64057
    View details
    Downtown Independence Commercial Building For Sale
    $1,300,000
    0.30 Acres

    Downtown Independence Commercial Building For Sale

    Well-maintained commercial building in Downtown Independence, suitable for various uses.

    120 S Liberty Street, Independence, MO 64050
    View details
    SINGLE_FAMILY - Independence, MO
    $730,000
    0.77 Acres

    SINGLE_FAMILY - Independence, MO

    Retail space · 0.77 Acres

    4541 S Noland Road, Independence, MO 64055
    View details
    Independence Commercial Building For Sale
    $365,000
    0.28 Acres

    Independence Commercial Building For Sale

    3,456 SF commercial building in high-traffic area.

    13717 E 39th Street, Independence, MO 64055
    View details
    Medical Suites Near Centerpoint Medical
    Contact for pricing
    200,000 SF

    Medical Suites Near Centerpoint Medical

    Divisible medical suites with hospital access and ample parking.

    19550 E 39th Street, Independence, MO 64057
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
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    Prime Land in Upper St Clair
    $50,000

    Prime Land in Upper St Clair

    Commercial land for lease in Upper St Clair, PA.

    2585 Maple Lane, Upper St Clair, PA 15241
    View details
    Grand Junction Commercial Land Opportunity
    $17,728 /Mo

    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
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    Grand Junction Commercial Land Lease
    $9,656 /Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details

    Independence, MO Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Independence, MO with 5 listings featured on our commercial real estate exchange. The current inventory includes 52,272,000 square feet of properties with an estimated lease value of $19 SF/Yr.

    Estimated lease rates for Medical Office Space in Independence, MO begin at $19 SF/Yr, with an average of $19 SF/Yr and extend to $19 SF/Yr.
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