Independence, MO Medical Office Space for Rent & Lease

Updated: Aug 21

Renovated Stand-Alone Office Building

307 E 23rd Street, Independence, MO 64055

$2,485/Mo

0.20 AC lot

Fully renovated stand‑alone office building
Approximately 14,385 vehicles/day along a commercial corridor
0.2 acres with C‑2 zoning
Multiple office/work areas, kitchen or break room, and restrooms
Lower‑level storage/utility space and freestanding pole sign

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Updated: Feb 24

Medical Clinic in Office Building

300 N Osage St, Independence, MO 64050

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5,270 sqft

5,270 SF move‑in ready second‑floor medical clinic in a 17,018 SF office building
Clinic layout includes 13 exam rooms plus lab space
Additional interior features: 5 private offices, IT room, and ample storage
Large break room with dedicated restroom
Walk‑in entry on the second floor from the parking structure with 30+ dedicated spots

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Commercial Lease, Independence, MO

3916 S Lynn Ct, Independence, MO 64055

$10 SF/Yr

Office and laboratory space with updated paint and flooring for dental or medical use.

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Medical Office Space with Exam Rooms

3800 S Elizabeth St, Independence, MO 64057

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2,700 sqft

Previously built-out medical office includes six rooms suitable for exam rooms or private offices.

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Medical Office Space with Exam Rooms

3800 S Elizabeth St, Independence, MO 64057

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1,200 sqft

Suite with six exam room or private office options, plus restroom and storage space.

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Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 5 Active listings in Independence, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Dental Office with Private Offices

625 W 39th St, Kansas City, MO 64111

Contact for pricing

3,200 sqft

Configured dental practice space includes treatment chairs, reception, support areas, and dedicated parking.

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High-Quality Office Space Available

Lees Summit, MO 64064

$6,448/Mo

AAA office space suitable for medical or professional services.

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Medical Office Space Available

2750 Clay Edwards Dr, Kansas City, MO

Contact for pricing

3,308 sqft 38.98 AC lot

Medical office space for rent, attached to hospital.

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Built-Out Medical Office Suite

1741 NE Douglas St, Lees Summit, MO 64086

Contact for pricing

7,678 sqft

First-floor suite built out for medical or office use, with access to Interstate 470.

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Similar Spaces for Sale in Independence, MO

Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

North Tower Office Building

1515 West Truman Road, Independence, MO 64050

Contact for pricing

144,449 sqft

Former hospital-affiliated office property that has been largely vacant since 2010.

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Medical Office Conversion Opportunity

13717-13723 E 39th St, Independence, MO 64055

$365,000

Former veterinary suite with reception, private offices, exam/treatment rooms, and extensive plumbing, ready for updates.

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Independence, MO Medical Office Space Lease Rates & Market Statistics

Explore 5 Medical Office Space listings for lease in Independence, MO on Realmo, a commercial real estate exchange covering the Independence area. The current inventory totals 9,170 square feet of properties.

Asking lease rates for Medical Office Space in Independence start at $10 SF/Yr, average $10 SF/Yr, and reach $10 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $10 SF/Yr is 28% below the Missouri state average of $13.94 SF/Yr.

Independence accounts for 26% of the 19 medical office space listings currently available across Jackson County, where nearby markets include Kansas City and Lees Summit. Medical Office Space listings make up 45% of the 11 Office Spaces currently for lease in Independence, with asking rates averaging $10 SF/Yr — 21% below the citywide Office Spaces average of $12.67 SF/Yr. Tenants comparing options may also consider Office Units (6 listings) elsewhere in the Independence market.