Poplar Bluff, MO Medical Office Space for Rent & Lease

Updated: May 8

Medical Rehabilitation Office Space

3999 Highway PP Suite 3, Poplar Bluff, MO 63901

$6,000/Mo

6,500 sq ft commercial space available for lease for $6,000/month
Previously used as a medical rehabilitation facility with a generous open layout
Central air conditioning and electric heat
Metal roof
Parking available with open parking and a parking lot

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Updated: Aug 2, 2025

Office Suite with Large Open Area

2201 N Westwood Boulevard #14, Poplar Bluff, MO 63901

$1,500/Mo

Large open room with many outlets
Most recently used as a call center
One restroom with a shower in the suite
Suite: 2201 N Westwood Boulevard #14, Poplar Bluff, MO 63901
Located in a high‑traffic retail center and shopping mall setting

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Historic Office Building

433 N Main St, Poplar Bluff, MO 63901

$5,000/Mo

Restored 1912 office building with reception, waiting rooms, kitchen, and flexible office and conference-room configuration.

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Medical Office Space Sublease

2210 Barron Road, Poplar Bluff, MO 63901

$12.50 SF/Yr

79,350 sqft

Sublease opportunity: medical office suites available in City, MO.

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Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 4 Active listings in Poplar Bluff, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Suite with Reception

1105 W Court St, Paragould, AR 72450

$10 SF/Yr

2,924 sqft

Flexible medical office space with reception, exam or patient rooms, and multiple restrooms.

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Turnkey Dental Office Suite

1105 W Court St, Paragould, AR 72450

$20 SF/Yr

Turnkey dental office space with reception, patient rooms, and supporting facilities for immediate medical use.

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Retail, Office and Medical Building

4212 E Johnson Ave, Jonesboro, AR 72405

Contact for pricing

15,000 sqft

Retail, office, or medical building with daytime traffic exposure over 31,000 cars daily.

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Medical Development Opportunity Near NEA

2097 Bridger Rd, Jonesboro, AR 72401

Contact for pricing

3,500 sqft

Premier medical development with direct access to NEA Baptist Hospital.

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Similar Spaces for Sale in Poplar Bluff, MO

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Three-Unit Commercial Office Building

1600 W Maud, Poplar Bluff, MO 63901

$379,900

Well-maintained commercial building with three currently rented units totaling 3,600 sq ft.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Office Development Land For Lease

1323 Strawfloor Drive, Jonesboro, AR 72401

Contact for pricing

4,000 sqft

2.43 acres for office development with build-to-suit opportunity.

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Corner Lot on Highway 72

30472 Highway 72, Madison, AL 35756

$5,000/Mo

1,875 sqft

1.7 acre corner lot zoned for commercial, medical, residential.

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Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

Contact for pricing

Outlot for ground lease or build-to-suit in South Lexington.

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Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 acre interstate-visible land for ground lease or build-to-suit.

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