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    Cass County, MO Medical Office Space for Lease

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    Saint Louis, MO Kansas City, MO Springfield, MO
    Medical Office Space For Rent
    $23 SF/Yr
    1,082 SF
    Medical Office Space For Rent

    2100 SE Shenandoah Dr, Lees Summit, MO

    Class A medical office space adjacent to Lee’s Summit Medical Center.
    • Directly adjacent to Lee’s Summit Medical Center (LSMC) and connected via a covered walkway.
    • New Class A common areas.
    • Completed in 2020.
    • Abundant parking.
    • Interstate visibility.
    Updated: Sep 3, 2025
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    Medical Office Space For Lease
    $25 SF/Yr
    6,560 SF
    Medical Office Space For Lease

    3601 NE Ralph Powell Rd, Lees Summit, MO

    Class B medical office building with attractive clinic setting.
    • Convenient access to I‑470
    • Ample surface parking spaces available
    • Attractive clinic setting with exam rooms
    • 1,960‑6,560 RSF available
    • Class B medical office building for lease
    Updated: Oct 21, 2025
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    Medical/Office Space Near Hospital
    $25 SF/Yr
    7,678 SF
    Medical/Office Space Near Hospital

    First floor medical/office suite adjacent to St. Luke’s East.

    1741 NE Douglas St, Lees Summit, MO

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    Medical Office Space Available
    $22 SF/Yr
    4,350 SF
    Medical Office Space Available

    Class A medical office space for lease with exam rooms.

    Lees Summit, MO 64064

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    High-Quality Office Space Available
    $29 SF/Yr
    High-Quality Office Space Available

    AAA office space suitable for medical or professional services.

    Lees Summit, MO 64064

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    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 5 Active listings in Cass County, MO, we suggest exploring alternatives. Similar 6 Properties for Sales.

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    Multi-Level Professional Building For Sale
    $2,050,000
    8,000 SF
    Multi-Level Professional Building For Sale

    Move-in ready medical/professional office with long-term tenant income.

    Lees Summit, MO 64082

    View details
    Commercial Building on Spacious Lot
    $900,000
    5,904 SF
    Commercial Building on Spacious Lot

    All-brick building with basement on a .938-acre lot.

    401 W Foxwood Drive, Raymore, MO 64083

    View details
    Belton Commercial Building For Sale
    $749,000
    2,356 SF
    Belton Commercial Building For Sale

    C-2 Zoned commercial building suitable for daycare or offices.

    502 W Markey Road, Belton, MO 64012

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    Dental Office with Five Operatories
    $1,600,000
    4,000 SF
    Dental Office with Five Operatories

    4,000 SF dental office with five operatories for sale.

    511 SW Jefferson St, Lees Summit, MO

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    Medical/Office Space For Sale
    $4,000,000
    Medical/Office Space For Sale

    Commercial real estate suitable for medical or office use.

    Lees Summit, MO 64086

    View details
    Retail Building in Prime Location
    Contact for pricing
    0.78 Acres
    Retail Building in Prime Location

    3,415 SF building on 0.785 acres in Belton, MO.

    404-410 E N Ave, Belton, MO

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Office Development Land For Lease
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    4,000 SF
    Office Development Land For Lease

    2.43 acres for office development with build-to-suit opportunity.

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    Kingery Highway Commercial Development Opportunity
    $85,000 SF/Yr
    Kingery Highway Commercial Development Opportunity

    High-visibility land for retail, car wash, or medical development.

    8501 & 8511 Kingery Highway, Willowbrook, IL 60527

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    Corner Lot on Highway 72
    $5,000/Mo
    1,875 SF
    Corner Lot on Highway 72

    1.7 acre corner lot zoned for commercial, medical, residential.

    30472 Highway 72, Madison, AL 35756

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    Beaumont Centre Outparcel Opportunity
    Contact for pricing
    Beaumont Centre Outparcel Opportunity

    Outparcel opportunity in established shopping center for ground lease.

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    Cass County, MO Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Cass County, MO with 5 listings featured on our commercial real estate exchange. The current inventory includes 19,670 square feet of properties with an estimated lease value of $95 SF/Yr.

    Estimated lease rates for Medical Office Space in Cass County, MO begin at $22 SF/Yr, with an average of $23 SF/Yr and extend to $25 SF/Yr.
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