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    Centennial, CO Medical Office Space for Lease

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    Aurora, CO Denver, CO Greenwood Village, CO
    7 results
    Updated Office Medical Building
    $24 SF/Yr
    29,788 SF

    Updated Office Medical Building

    6979 S Holly Circle, Centennial, CO 80112

    29,755 SF office medical building with ample parking.

    • Updated 29,755 SF office medical building.
    • Minutes from I‑25 and C‑470.
    • Ample parking.
    • Remodeled 2‑story sky‑lit entrance.
    • Proactive professional property management with meticulous attention to detail and cleanliness.
    Updated: Nov 21, 2025
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    Move-in Ready Medical Space
    $28 SF/Yr
    4,400 SF

    Move-in Ready Medical Space

    20270 E Smoky Hill Rd, Centennial, CO

    Medical space with reserved parking and signage options available for rent.

    • Move‑in Ready Medical Space
    • Features a Lab, MA Work Stations, and X‑Ray Room
    • Enjoy the convenience of 5 Reserved Parking Spaces
    • Furniture and Equipment Can Be Included
    • Multiple On‑Building Signage Options available
    Updated: Oct 4, 2024
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    Medical Co-working Space Available
    Contact for pricing
    1,560 SF

    Medical Co-working Space Available

    Short-term medical co-working space for rent in Centennial, Colorado.

    6886 S Yosemite St, Centennial, CO
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    Centennial Med-Tail Space Available
    $17 SF/Yr
    23,789 SF

    Centennial Med-Tail Space Available

    Retail frontage space in mixed medical/retail building for rent.

    5657 S Himalaya Street #250, Centennial, CO 80015
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    Centennial Med-Tail Space Available
    $17 SF/Yr
    23,789 SF

    Centennial Med-Tail Space Available

    Retail frontage space in mixed medical/retail building for rent.

    5657 S Himalaya Street #250, Centennial, CO 80015
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    Centennial Office/Medical Space Available
    $19 SF/Yr

    Centennial Office/Medical Space Available

    Office and medical spaces for lease with 24-hour access.

    6650 S Vine St, Centennial, CO 80121
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    Centennial Office/Medical Space Available
    $15 SF/Yr
    2,621 SF

    Centennial Office/Medical Space Available

    Office and medical space for lease in Centennial, Colorado.

    13275 E Fremont Pl, Centennial, CO 80112
    View details
    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 7 Active listings in Centennial, CO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Move-In Ready Medical/Office Space
    $29 SF/Yr
    1,993 SF

    Move-In Ready Medical/Office Space

    Available medical/office space near Parker Adventist and Children’s Hospital.

    19284 Cottonwood Dr, Parker, CO
    View details
    Medical Office Space Near Hospital
    Contact for pricing
    3,334 SF

    Medical Office Space Near Hospital

    Medical office space adjacent to Parker Adventist Hospital.

    9395-9399 Crown Crest Blvd, Parker, CO
    View details
    Turnkey Clinic Near Sky Ridge
    Contact for pricing
    3,479 SF

    Turnkey Clinic Near Sky Ridge

    Turnkey clinic near HCA HealthONE Sky Ridge hospital.

    10099 Ridgegate Pkwy, Lone Tree, CO
    View details
    Medical and Healthcare Facility Available
    Contact for pricing
    5,477 SF

    Medical and Healthcare Facility Available

    Medical facility with operating rooms, nursery, and treatment center.

    10107 Ridgegate Pkwy, Lone Tree, CO
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Grand Junction Commercial Land Opportunity
    $17,728/Mo

    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
    View details
    Grand Junction Commercial Land Lease
    $9,656/Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details
    El Paso Commercial Land Lease
    $3,600/Mo

    El Paso Commercial Land Lease

    Commercial land for lease in a strategic El Paso location.

    5538 E Paisano Drive, El Paso, TX 79905
    View details
    Office Development Land For Lease
    Contact for pricing
    4,000 SF

    Office Development Land For Lease

    2.43 acres for office development with build-to-suit opportunity.

    1323 Strawfloor Drive, Jonesboro, AR 72401
    View details

    Centennial, CO Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Centennial, CO with 7 listings featured on our commercial real estate exchange. The current inventory includes 86,510 square feet of properties with an estimated lease value of $120 SF/Yr.

    Estimated lease rates for Medical Office Space in Centennial, CO begin at $15 SF/Yr, with an average of $20 SF/Yr and extend to $28 SF/Yr.
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    Most Searched ZIP Codes in Centennial, CO

    • 80015
    • 80112
    • 80121

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