Medical Space

Centennial, CO Medical Office Space for Lease

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Updated Office Medical Building
Updated: Nov 21, 2025
Updated Office Medical Building

6979 S Holly Circle, Centennial, CO 80112

$24 SF/Yr
29,788 sqft
Updated 29,755 SF office medical building.
Minutes from I‑25 and C‑470.
Ample parking.
Remodeled 2‑story sky‑lit entrance.
Proactive professional property management with meticulous attention to detail and cleanliness.
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Medical Office Suite with Patio
Updated: Jul 3
Medical Office Suite with Patio

6650 S Vine St, Centennial, CO 80121

Contact for pricing
2,884 sqft
Move‑in‑ready office suite with a kitchen and multiple offices
In‑place plumbing and compressed air for medical use
Dental/endodontic space with reception, private restroom, multiple offices, and treatment chairs
Existing x‑ray equipment infrastructure in place
Ample parking and on‑site management
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Move-in Ready Medical Office Suite with Patios
Move-in Ready Medical Office Suite with Patios

6650 S Vine St, Centennial, CO 80121

Contact for pricing
1,253 sqft

Move-in ready medical office suite options with in-place utilities for light medical use.

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Centennial Med-Tail Space For Rent
Centennial Med-Tail Space For Rent

5657 S Himalaya St 250, Centennial, CO 80015

$17 SF/Yr
1.92 AC lot

Retail frontage space with open layout and private offices.

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Lower Level Medical Office Suite
Lower Level Medical Office Suite

6650 S Vine St, Centennial, CO 80121

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2,431 sqft

Lower level suite with three private rooms, reception area, patio, and washer/dryer connections.

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Medical Office Suite with Patio
Medical Office Suite with Patio

6650 S Vine St, Centennial, CO 80121

Contact for pricing
2,057 sqft

Move-in-ready dental/medical suite includes reception, private restroom, multiple offices, and treatment chair space.

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Lower Level Medical Office Suite
Lower Level Medical Office Suite

6650 S Vine St, Centennial, CO 80121

Contact for pricing
1,288 sqft

Lower level suite with three offices, a reception/open area, and a private patio with natural light.

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Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 7 Active listings in Centennial, CO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Ground-Floor Medical Office Suite
Ground-Floor Medical Office Suite

384 Inverness Pkwy, Englewood, CO 80112

$22 SF/Yr
2,992 sqft

Remodeled ground-floor suite with free surface parking and built-in nursing station for office or medical use.

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Professional Office and Medical Suites
Professional Office and Medical Suites

8 West Dry Creek Circle, Littleton, CO 80122

$22 SF/Yr

Office and medical-dental space within Highline Professional Center, with convenient access near major roadways and amenities.

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Littleton Office Sublease Opportunity
Littleton Office Sublease Opportunity

7261 S Broadway, Littleton, CO

Contact for pricing
1,500 sqft 0.99 AC lot

Office sublease with exam rooms, provider offices, and shared spaces.

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Retail Spaces in Mixed-Use Development
Retail Spaces in Mixed-Use Development

504 E Hampden Ave, Englewood, CO 80113

Contact for pricing
1,718 sqft

Construction is complete, and the remaining retail spaces are ready for tenant finish in a five-story project.

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Similar Spaces for Sale in Centennial, CO

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Office Building with Conference Rooms
Office Building with Conference Rooms

6911 S Yosemite, Centennial, CO 80112

$2,450,000

Standalone office property with landscaped outdoor space, upgraded finishes, and separate upper- and lower-level work areas.

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Centennial, CO Medical Office Space Lease Rates & Market Statistics

Browse 7 Medical Office Space listings for lease in Centennial, CO on Realmo, a commercial real estate marketplace serving the Centennial area. The current inventory totals 39,701 square feet of properties.

Asking lease rates for Medical Office Space in Centennial start at $17 SF/Yr, average $20.50 SF/Yr, and reach $24 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $20.50 SF/Yr is 7% below the Colorado state average of $22.05 SF/Yr.

Centennial accounts for 18% of the 38 medical office space listings currently available across Arapahoe County, where nearby markets include Denver and Aurora. Medical Office Space listings make up 30% of the 23 Office Spaces currently for lease in Centennial, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Office Units (18 listings) elsewhere in the Centennial market.

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