Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Medical Space
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Rancho Santa Margarita, CA Medical Office Space for Lease

    Notify Me
    List
    Map
    Medical Office Condo For Rent
    $2 SF/Yr
    2,360 SF

    Medical Office Condo For Rent

    30212 Tomas, Rancho Santa Margarita, CA

    Medical office condo featuring private offices, conference room, and balcony.

    • Six private offices ideal for medical practice
    • Conference room for meetings and collaboration
    • Reception area for patient greeting and administration
    • Break room for staff convenience
    • Private balcony offering a relaxing space
    Updated: Sep 23, 2025
    View details
    Medical Office Space For Rent
    Contact for pricing
    18,400 SF

    Medical Office Space For Rent

    29472 Avenida de las Banderas, Rancho Santa Margarita, CA 92688

    Medical office space in Rancho Santa Margarita available for lease.

    • Prime location in Rancho Santa Margarita with strong visibility from Antonio Parkway.
    • Excellent accessibility: minutes from the 241 Toll Road and convenient access to surrounding communities.
    • Large patient base: Serves approximately 387,000 patients within a 15‑minute drive.
    • Well‑appointed 5,006 SF medical office suite (divisible to 3,000 RSF) with 14 exam rooms, procedure room, 3 private offices, and dual waiting rooms.
    • Under new ownership and professional management with Archer Property Partners.
    Updated: Feb 23
    View details
    Medical Office Sublease Opportunity
    Contact for pricing
    2,835 SF

    Medical Office Sublease Opportunity

    Medical office space available for sublease in Rancho Santa Margarita.

    22032 El Paseo, Rancho Santa Margarita, CA 92688
    View details
    Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 3 Active listings in Rancho Santa Margarita, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Renovated Medical Office Building
    $2 SF/Yr
    21,300 SF

    Renovated Medical Office Building

    Recently renovated medical office building near Saddleback Hospital.

    24953 Paseo De Valencia Bldg C, Laguna Hills, CA 92653
    View details
    30250 Rancho Viejo Rd
    $28 SF/Yr

    30250 Rancho Viejo Rd

    Office For Lease

    30250 Rancho Viejo Rd, San Juan Capistrano, CA 92675, San Juan Capistrano, CA 92675
    View details
    30240 Rancho Viejo Rd
    $60 SF/Yr

    30240 Rancho Viejo Rd

    Office For Lease

    30240 Rancho Viejo Rd, San Juan Capistrano, CA 92675, San Juan Capistrano, CA 92675
    View details
    Medical Office Space For Rent
    Contact for pricing
    40,000 SF

    Medical Office Space For Rent

    New medical office space adjacent to Saddleback Memorial Hospital.

    24401 Calle De La Louisa, Laguna Hills, CA 92653
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Grand Junction Commercial Land Lease
    $9,656 /Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details
    Grand Junction Commercial Land Opportunity
    $17,728 /Mo

    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
    View details
    El Paso Commercial Land Lease
    $3,600 /Mo

    El Paso Commercial Land Lease

    Commercial land for lease in a strategic El Paso location.

    5538 E Paisano Drive, El Paso, TX 79905
    View details
    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details

    Rancho Santa Margarita, CA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Rancho Santa Margarita, CA with 3 listings featured on our commercial real estate exchange. The current inventory includes 70,567,200 square feet of properties with an estimated lease value of $2 SF/Yr.

    Estimated lease rates for Medical Office Space in Rancho Santa Margarita, CA begin at $2 SF/Yr, with an average of $2 SF/Yr and extend to $2 SF/Yr.
    List
    Map

    Browse Medical Office Space for Lease Near Rancho Santa Margarita, CA

    Popular Searches in Rancho Santa Margarita, CA

    Most Searched ZIP Codes in Rancho Santa Margarita, CA

    • 92688

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!